17 Possible Causes for Liver Biopsy showing Bile Duct Necrosis

  • Ascending Cholangitis

    Hurrah! You know all the cards! Please wait - loading[…] Bile contains c......, b..... p..... (from broken down Hb), and p..... If the concentrations vary, different stones may form. What are the different types of stones that may form and some risk factors? Describe the anatomical positions required for stones to cause[…][goconqr.com]

  • Primary Sclerosing Cholangitis

    Primary sclerosing cholangitis ( PSC ) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts which normally allow bile to drain from the gallbladder. Affected individuals may have no symptoms or may experience signs and symptoms of liver disease[…][en.wikipedia.org]

  • Trovafloxacin

    A biopsy specimen of the liver showed centrilobular and focal periportal necrosis and eosinophilic infiltration ( Figure 1 ).[nejm.org] Neither gallstones nor ascites was seen; the bile ducts were not distended.[nejm.org] Ultrasonography of the abdomen showed coarse echogenicity, a finding consistent with necrosis.[nejm.org]

  • Granulomatous Hepatitis

    In histopathology, a liver biopsy specimen showed mild spotty necrosis of hepatocytes, marked cholestasis in parenchyma, and some granulomas in the portal area.[e-cmh.org] There were vacuolar degeneration in the interlobular bile ducts and ductopenia in the portal tracts.[e-cmh.org]

  • Bile Acid Synthesis Defect with Cholestasis and Malabsorption

    Liver biopsy showed piecemeal necrosis with early cirrhosis and no bile stasis or bile duct proliferation.[pediatriconcall.com] Ultrasound abdomen showed mild hepatosplenomegaly with gall bladder sludge.[pediatriconcall.com] ., partial thromboplastin time 31.7 sec, cholesterol 190 mg, dl and serum bile acids of 152.4 µmol, L {Normal 0 - 10 µmol, L}.[pediatriconcall.com]

  • Familial Hypercholanemia

    Liver biopsy showed piecemeal necrosis with early cirrhosis and no bile stasis or bile duct proliferation.[pediatriconcall.com] Ultrasound abdomen showed mild hepatosplenomegaly with gall bladder sludge.[pediatriconcall.com] ., partial thromboplastin time 31.7 sec, cholesterol 190 mg, dl and serum bile acids of 152.4 µmol, L {Normal 0 - 10 µmol, L}.[pediatriconcall.com]

  • Bile Duct Stricture

    […] dilated IHBR and showed stricture of CHD at liver hilum; Histopathological examination of biopsy from bile duct revealed epitheliod cell granulomas and caseous necrosis;[oapublishinglondon.com] Iwai et al. 12 A 36-year-old woman presented with painless progressive jaundice; CT of abdomen revealed dilated IHDR andmultiple hypo dense lesions in liver; ERCP confirmed[oapublishinglondon.com]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] duct proliferation.[merckmanuals.com] Such cases rarely develop into clinically important liver disease or cirrhosis.[merckmanuals.com]

  • Liver Disease

    Liver biopsies in such cases show features of both PBC (granulomatous inflammation and bile duct lesions) and AIH (piecemeal necrosis and spotty hepatocyte necrosis) ( Figure[nature.com] In general, in low-titer AMA-positive patients, if the liver biopsy shows features typical of AIH, such as prominent piecemeal necrosis, numerous plasma cells in the inflammatory[nature.com] […] infiltrate, and lobular hepatitis, without prominent bile duct destruction, and liver tests favor a hepatitic process over chronic cholestasis, clinicians will often consider[nature.com]

  • Short Stature - Optic Atrophy - Pelger-Huët Anomaly Syndrome

    There was mild acute hepatitis with small foci of lobular necrosis and chronic inflammation. No portal fibrosis or bile duct damage was identified.[saudijgastro.com] As there was no definitive infectious or metabolic cause of hepatitis, percutaneous liver biopsy was undertaken, which showed nonspecific acute hepatocellular injury.[saudijgastro.com]

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