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49 Possible Causes for Liver Biopsy showing Hepatocyte Necrosis

  • Viral Hepatitis

    It usually shows focal, sometimes extensive, hemorrhagic or coagulative necrosis of the hepatocytes with limited infammatory response (Figure 2).[] Liver biopsy is essential to establish the diagnosis of HSV hepatitis, especially in pregnancy.[] In immunocompromised hosts, HSV hepatitis has occurred during primary and, rarely, during recurrent infection, with a triad of fever, leukopenia and markedly elevated liver[]

  • Drug-induced Toxic Hepatitis

    The second liver biopsy showed chronic hepatitis with mild activity and septal fibrosis, despite clinical and biochemical resolution.[] Lobular liver cell damage ameliorated, no bridging necrosis or multiacinar necrosis was found and small regenerative hepatocytes were seen (figure 1B ).[]

  • Massive Hepatic Necrosis

    Unlike their experience, our patient recovered without fibrosis or cirrhosis, although his liver showed not only macroscopic regenerative nodules in massive hepatic necrosis[] […] of the explanted small native left lobe but also fibrosis intermixed with remarkably regenerative hepatocytes in needle biopsies by 6 months after APOLT.[]

  • Alcoholic Hepatitis

    Aims: Alcoholic hepatitis is a severe complication of alcoholism, associated with high short-term mortality. Although pathogenesis remains obscure, it is generally accepted that lipopolysaccharide-induced cytokine secretion with further generation of reactive oxygen species (ROS) play outstanding roles. Prognosis is[…][]

  • Hepatitis B

    The management of hepatitis B Summary Chronic hepatitis B affects almost 1% of Australians, many of whom are born in endemic areas outside Australia. This infection can shorten lifespan, usually because of cirrhosis or hepatocellular carcinoma. Most patients acquire the infection perinatally or in childhood before[…][]

  • Toxic Hepatitis

    Aloe has been widely used in phytomedicine. Phytomedicine describes aloe as a herb which has anti-inflammatory, anti-proliferative, anti-aging effects. In recent years several cases of aloe-induced hepatotoxicity were reported. But its pharmacokinetics and toxicity are poorly described in the literature. Here we[…][]

  • Acetaminophen Overdose

    J Med Toxicol. 2016 Mar;12(1):100-6. doi: 10.1007/s13181-015-0504-x. Author information 1 Department of Emergency Medicine, Division of Medical Toxicology, University of Southern California, Los Angeles, CA, USA. 2 Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ, USA.[…][]

  • Hereditary Fructose Intolerance

    Hereditary fructose intolerance is an inborn error of fructose metabolism caused by a deficiency of the enzyme aldolase B. [1] Individuals affected with HFI are asymptomatic until they ingest fructose, sucrose, or sorbitol. If fructose is ingested, the enzymatic block at aldolase B causes an accumulation of[…][]

  • Hepatitis A

    Hepatitis A (cont.) Hepatitis A Symptoms Many people with HAV infection have no symptoms at all. Sometimes symptoms are so mild that they go unnoticed. Older people are more likely to have symptoms than children. People who do not have symptoms can still spread the virus. Symptoms of hepatitis A usually develop[…][]

  • Chronic Active Hepatitis

    An elderly woman receiving long term treatment with prednisone and azathioprine for cryptogenic chronic active hepatitis developed granulomatous lipophagic panniculitis and temporal arteritis. The lymphoplasmahistiocytic inflammatory reaction pattern is common to this patient's three diseases. It is suggested that an[…][]

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