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12 Possible Causes for Liver Biopsy showing Hepatocyte Necrosis, Liver Biopsy showing Periportal Necrosis

  • Viral Hepatitis

    It usually shows focal, sometimes extensive, hemorrhagic or coagulative necrosis of the hepatocytes with limited infammatory response (Figure 2).[doi.org] Liver biopsy is essential to establish the diagnosis of HSV hepatitis, especially in pregnancy.[doi.org] In immunocompromised hosts, HSV hepatitis has occurred during primary and, rarely, during recurrent infection, with a triad of fever, leukopenia and markedly elevated liver[doi.org]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Unlike their experience, our patient recovered without fibrosis or cirrhosis, although his liver showed not only macroscopic regenerative nodules in massive hepatic necrosis[nature.com] FIGURE 2 Massive hepatic necrosis, and ductular cells from postoperative day (POD) 0 to POD 7 after auxiliary partial orthotopic liver transplantation.[nature.com]

  • Hepatitis B

    The risk of de novo hepatitis B virus infection is lower after liver transplant using hepatitis B core antibody-negative donors into negative recipients versus hepatitis B core antibody-positive donors but can occur. Here, we present a 34-year-old male patient with acute de novo hepatitis B virus that developed 7[…][ncbi.nlm.nih.gov]

  • Hepatitis A

    IRMNG taxon details Hepatitis A virus IRMNG_ID 11459942 (urn:lsid:irmng.org:taxname:11459942) Classification Status Rank Parent Environment Fossil range Original description Taxonomic citation IRMNG (2018). Hepatitis A virus. Accessed at: on 2019-06-13 Taxonomic edit history 2011-08-03 22:00:00Z created 2011-12-31[…][irmng.org]

  • Aflatoxicosis

    OBJECTIVES: During January-June 2004, an aflatoxicosis outbreak in eastern Kenya resulted in 317 cases and 125 deaths. We conducted a case-control study to identify risk factors for contamination of implicated maize and, for the first time, quantitated biomarkers associated with acute aflatoxicosis. DESIGN: We[…][ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Such cases rarely develop into clinically important liver disease or cirrhosis.[merckmanuals.com]

  • Drug-induced Cholestatic Hepatitis

    Liver biopsy showed prominent spotty necrosis and focal confluent necrosis. Portal and mild periportal lymphomononuclear inflammation.[jcdr.net] He underwent transjugular liver biopsy which showed mixed cholestatic and hepatocellular injury pattern with acute hepatitis, hepatocyte necrosis, extensive intrahepatic and[karger.com] The abdomen MRI upon admission showed no cirrhosis and no intra- and extrahepatic biliary dilatation.[karger.com]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Liver biopsies in such cases show features of both PBC (granulomatous inflammation and bile duct lesions) and AIH (piecemeal necrosis and spotty hepatocyte necrosis) ( Figure[doi.org] Such cases rarely develop into clinically important liver disease or cirrhosis.[merckmanuals.com]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Liver biopsy normally shows ballooning degeneration, focal hepatocyte necrosis, and neutrophilic infiltration[ 4, 20 ].[doi.org] biopsy shows identical findings in patients with ASH and NASH, specifically, the presence of polymorphonuclear infiltration, hepatocyte necrosis and apoptosis in the form[en.wikipedia.org]

  • Iron Poisoning

    Liver biopsy in a patient with hepatotoxicity will show hepatocellular necrosis in the periportal hepatocytes (Zone 1).[meducator3.net] Liver biopsy in a patient with hepatotoxicity will show hepatocellular necrosis in the periportal hepatocytes (Zone 1).[meducator3.net]

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