30 Possible Causes for Liver Biopsy showing Periportal Fibrosis

  • Chronic Hepatitis C

    Table 1 shows an approximate correspondence between these systems, both for fibrosis (architectural alteration) and for periportal/lobular activity.[scielo.br] Protocol of Histological Evaluation for Liver Biopsies of Patients with Chronic viral Hepatitis This protocol can be applied to several etiologies of chronic hepatitis, including[scielo.br]

  • Mitochondrial DNA Depletion Syndrome 3 Type Hepatocerebral

    ; Cholestasis; Steatosis; Jaundice; Hepatocellular loss; Hepatocellular necrosis; Periportal fibrosis; Pseudoacinar formation; Electron microscopy shows increased and abnormal[genome.jp] […] tissue shows 80 to 99% depletion of mitochondrial DNA (mtDNA) with decreased activities of mitochondrial-encoded respiratory chain complexes; Biopsy shows micronodular cirrhosis[genome.jp] Nystagmus; Disconjugate eye movements; Optic dysplasia ABDOMEN: [External features]; Ascites; Portal hypertension; [Liver]; Hepatomegaly; Abnormal liver function tests; Liver[genome.jp]

  • Schistosomiasis Japonica

    Schistosomiasis is caused by several parasitic schistosome worms, leading to two major forms of clinical disease. Urinary schistosomiasis is caused by Schistosoma haematobium, whilst intestinal schistosomiasis is caused by Schistosoma mansoni (in Africa, Middle East, the Caribbean and Latin America) or Schistosoma[…][ntdmodelling.org]

  • Hepatitis C

    Hepatitis C is a liver infection caused by the Hepatitis C virus (HCV). Hepatitis C is a blood-borne virus. Today, most people become infected with the Hepatitis C virus by sharing needles or other equipment to inject drugs. For some people, hepatitis C is a short-term illness but for 70%–85% of people who become[…][cdc.gov]

  • Primary Sclerosing Cholangitis

    Primary sclerosing cholangitis ( PSC ) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts which normally allow bile to drain from the gallbladder. Affected individuals may have no symptoms or may experience signs and symptoms of liver disease[…][en.wikipedia.org]

  • Alcoholic Hepatitis

    Alcoholic hepatitis is hepatitis (inflammation of the liver ) due to excessive intake of alcohol . [1] It is usually found in association with fatty liver , an early stage of alcoholic liver disease , and may contribute to the progression of fibrosis, leading to cirrhosis . Signs and symptoms of alcoholic hepatitis include[…][en.wikipedia.org]

  • Cryoglobulinemic Vasculitis

    Liver biopsy revealed chronic hepatitis, Ishak's grading 1 0 1 2 4 with stage 1 fibrosis [Figure 1] .[ijpmonline.org] Figure 1: Liver biopsy showing mild chronic periportal inflammation, occasional foci of lobular inflammation and mild ballooning of hepatocytes (Ishak's grading 4) Click here[ijpmonline.org]

  • Progressive Familial Intrahepatic Cholestasis 4

    Liver biopsy showed extensive ductular reaction with portal and periportal fibrosis.[ghrnet.org] Liver biopsy, immunohistochemical analysis for MDR3 protein expression and molecular genetic analysis were done for the patient.[ghrnet.org]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Such cases rarely develop into clinically important liver disease or cirrhosis.[merckmanuals.com] Mild cases may have only minor hepatocellular necrosis and inflammatory cell infiltration, usually in portal regions, with normal acinar architecture and little or no fibrosis[merckmanuals.com]

  • Aagenaes Syndrome

    Focal pericellular fibrosis was observed around some of the periportal hepatocytes.[journals.lww.com] Liver biopsy showed marked intracellular and canalicular cholestasis . The hepatocytes showed diffuse hydropic and ballooning degeneration.[journals.lww.com]

Further symptoms