Create issue ticket

539 Possible Causes for Liver Biopsy showing Periportal Necrosis, Recurrent Jaundice

  • Primary Sclerosing Cholangitis

    Presentations of primary sclerosing cholangitis History: Fatigue Pruritus Weight loss Right upper quadrant (RUQ) pain Recurrent biliary infections Examination: Jaundice Hepatomegaly[] Benign recurrent intrahepatic cholestasis is characterized by episodic jaundice and pruritus lasting for several weeks to months, with long symptom-free intervals.[] Endoscopic treatment of biliary strictures often improves liver biochemistry and pruritus and may reduce the risk of recurrent cholangitis.[]

  • Isoniazid Hepatitis

    […] who was also IgM anti-HAV positive and who later tolerated therapy without recurrence).[] […] with rates similar for all three regimens [starting agents at full doses or gradual escalation], onset in 5-35 days, none fatal and few with jaundice).[] PubMed Citation (42 year old man developed rash followed by jaundice 1 month after starting streptomycin, PAS and isoniazid for active tuberculosis; positive lymphocyte stimulation[]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[] Dubin-Johnson Syndrome Sprinz-Nelson Syndrome Due to defective transport of bilirubin-glucuronide through hepatocytes into canaliculi Characterized by mild, recurrent jaundice[] On the 14th day icteric serum was noted, although the patient was never again described as jaundiced.[]

  • Drug-induced Cholestatic Hepatitis

    Liver biopsy showed prominent spotty necrosis and focal confluent necrosis. Portal and mild periportal lymphomononuclear inflammation.[] Oral contraceptives are contraindicated in patients with a history of recurrent jaundice of pregnancy.[] Benign recurrent intrahepatic cholestasis is unlikely as it usually presents at a young age and the patient failed to give any prior history of jaundice.[]

  • Primary Biliary Cirrhosis

    Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[] -Patients with rapidly progressive jaundice or recurrent cholangitis in the setting of PSC should undergo cholangiography to identify any of these three features.[] Benign recurrent intrahepatic cholestasis is characterized by episodic jaundice and pruritus lasting for several weeks to months, with long symptom-free intervals.[]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[] Other symptoms may include: Fever Abdominal pain Arthritis Anemia Dry eyes and mouth Recurrent jaundice frequently develops in severe cases Lack of menstrual periods Normally[] All other causes of cholestatic jaundice were ruled out.[]

  • Hepatitis A

    Symptoms may include fatigue, fever, nausea, myalgia, jaundice and pruritus. Recurrence and chronic hepatitis do not usually occur.[] Around 10–15% of people experience a recurrence of symptoms during the six months after the initial infection.[] When symptoms occur, they typically last eight weeks and may include nausea, vomiting, diarrhea, jaundice, fever, and abdominal pain.[]

  • Cholelithiasis

    In the CBD: Obstructive jaundice.. Liver failure. Cholangitis. Acute or recurrent pancreatitis. In the pancreas: Acute Pancreatitis. Acute relapsing Pancreatitis.[] - known as Mirizzi syndrome. [3] Can be associated with jaundice. [4] The two types of gallstones: Cholesterol stones.[] Severe, colicky, recurrent right-sided hypochondriac pain Pain may radiate to the shoulder and upper back Fever and chills or Alternating fever and chills Bitter taste in[]

    Missing: Liver Biopsy showing Periportal Necrosis
  • Choledocholithiasis

    jaundice or cholangitis 2.89, 95% CI 0.58 to 14.37) and Targarona 1996 (RR recurrent jaundice or cholangitis 2.22, 95% CI 0.91 to 5.37).[] CBDS easily lead to biliary obstruction, secondary cholangitis, pancreatitis, and obstructive jaundice, even endanger life.[] Jaundice and general malaise subsided after the procedure. A laparoscopic cholecystectomy and intraoperative cholangiography were performed 10 days after the ERCP.[]

    Missing: Liver Biopsy showing Periportal Necrosis
  • Cholestasis

    Intrahepatic cholestasis of pregnancy Also known as recurrent cholestasis of pregnancy, obstetric cholestasis, cholestasis of pregnancy, recurrent jaundice of pregnancy, cholestatic[] Benign recurrent intrahepatic cholestasis (BRIC) is characterised by recurrent episodes of jaundice, severe pruritus and low or normal serum γ-glutamyltransferase activity[] Clinical signs of cholestasis (discolored stools, dark urine) usually appear in the first months of life with recurrent or permanent jaundice associated with hepatomegaly[]

    Missing: Liver Biopsy showing Periportal Necrosis

Further symptoms

Similar symptoms