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3 Possible Causes for Liver Biopsy Shows Increased Lipid Droplets

  • Cholesterol Ester Storage Disease

    Light microscopy of a liver biopsy showed increased intracytoplasmic glycogen and small lipid droplets in hepatocytes.[lipidworld.biomedcentral.com]

  • Reye Syndrome

    Liver biopsy showed diffuse lipid droplet infiltration in 2, focal infiltration in 1, and normal morphology in 1.[ncbi.nlm.nih.gov] Because of mild muscle weakness, she had repeated muscle biopsies which showed markedly increased amounts of lipid droplets, predominantly in type 1 fibers.[ncbi.nlm.nih.gov] A liver biopsy showed diffuse accumulation of lipid droplets in swollen hepatocytes, and abnormal urinary metabolites included beta-hydroxy-beta-methyl glutarate (HMG), beta-methylglutaconate[ncbi.nlm.nih.gov]

  • HMG-CoA Lyase Deficiency

    A liver biopsy showed diffuse accumulation of lipid droplets in swollen hepatocytes, and abnormal urinary metabolites included β-hydroxy-β-methyl glutarate (HMG), β-methylglutaconate[neurology.org] Mamer First published July 1, 1980, DOI: Abstract A 2-year-old boy had acute fever, malaise, and somnolence with hepatomegaly, increased blood ammonia content (388 μM), high[neurology.org]

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