Liver Disorder in Pregnancy: Causes & Reasons

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Possible Causes for Liver Disorder in Pregnancy

Acute Fatty Liver of Pregnancy

2015 ICD-9-CM Diagnosis Code 646.7 Liver and biliary tract disorders in pregnancy, unspec as to episode of care or not applicable There are 3 ICD-9-CM codes below 646.7 that [icd9data.com]

Some liver disorders occur only during pregnancy. [msdmanuals.com]

Symptoms of fatty liver of pregnancy include nausea, vomiting, abdominal discomfort, and jaundice. The disorder may rapidly worsen, and liver failure may develop. [msdmanuals.com]

Cholestasis of Pregnancy

It occurs in 3% to 10% of all pregnancies. Several disorders contribute to liver disease in pregnancy ( Box 1 ). [clevelandclinicmeded.com]

Obstetric Cholestasis (OC) or Intrahepatic Cholestasis of Pregnancy (ICP) is a liver disorder that occurs in around one in 140 pregnancies in the UK, where the normal flow [britishlivertrust.org.uk]

It could be peculiar to the pregnancy viz., acute fatty liver of pregnancy, recurrent cholestatic jaundice in pregnancy and jaundice complicating toxemia of pregnancy. [ijrcog.org]

HELLP Syndrome

Although the association of hemolysis, low platelets and liver dysfunction with hypertensive disorders of pregnancy was known since 1954, the term HELLP syndrome was first [slideshare.net]

Abstract HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome represents a life-threatening pregnancy disorder with high fetal and maternal mortality, but its [ncbi.nlm.nih.gov]

Abstract Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during [ncbi.nlm.nih.gov]

Acute Cholecystitis

Intrahepatic cholestasis of pregnancy Intrahepatic cholestasis of pregnancy (ICP) is a potentially serious liver disorder that can develop in pregnancy. [nhs.uk]

Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis (OC), is a liver disorder that can develop during pregnancy. [tommys.org]

Intrahepatic cholestasis of pregnancy is a liver disorder that occurs in pregnant women. [ghr.nlm.nih.gov]

Biliary Colic

Sickle cell), liver cirrhosis R/F for stones becoming symptomatic: smoking, parity (previously carried pregnancies to viable gestational age). [clumsylostmedicalstudent.wordpress.com]

Pigment stones: haemolytic disorders (e.g. [clumsylostmedicalstudent.wordpress.com]

Viral Hepatitis

Disease, Metabolic Syndrome, Insulin Resistance, Autoimmune Disorders, Cirrhosis, Pregnancy, Wilson Disease, Hemochromatosis Screening: Hepatitis B: Newborns, Teens, Young [labtestsonline.org]

Copper, Alpha-1 Antitrypsin, Acetaminophen, Ethanol, Drug Abuse Testing, Emergency and Overdose Drug Testing, Comprehensive Metabolic Panel Conditions: Jaundice, Alcoholism, Liver [labtestsonline.org]

Eclampsia

Endocrine Disorders of Pregnancy -- Gastrointestinal Disease in Pregnancy -- Diseases of the Liver, Biliary System, and Pancreas -- Pregnancy and Rheumatic Diseases -- Neurologic [worldcat.org]

Convulsions during pregnancy that are unrelated to pre-eclampsia need to be distinguished from eclampsia. [en.wikipedia.org]

Anemia and Pregnancy -- Malignancy and Pregnancy -- Renal Disorders -- Respiratory Diseases in Pregnancy -- Diabetes in Pregnancy -- Thyroid Disease and Pregnancy -- Other [worldcat.org]

Cholelithiasis

OBJECTIVE: The aim of this study was to examine the etiology of gallstones in children and responses to ursodeoxycholic acid (UDCA) treatment. METHODS: 74 children with cholelithiasis were recruited, and underwent ultrasonography to detect gallstones. All relevant clinical information was recorded in a structured[…] [ncbi.nlm.nih.gov]

Choledocholithiasis

Intern Med. 2008;47(24):2169-70. Epub 2008 Dec 15. Author information 1 Disciplina de Hematologia e Hemoterapia, Universidade Federal de São Paulo, São Paulo, Brazil. perlavicari@hemato.epm.br Abstract Choledocholithiasis can be caused by either primary or secondary bile duct stones. Although patients with sickle cell[…] [ncbi.nlm.nih.gov]

Intrahepatic Cholestasis

Intrahepatic Cholestasis of Pregnancy (ICP) is a pregnancy Liver -related liver disorder and also known as Obstetrics Cholestasis (OCP). [slideshare.net]

A number of liver disorders are specific to pregnancy. [ncbi.nlm.nih.gov]

Abstract Intrahepatic cholestasis of pregnancy (ICP) is a disorder of liver function, commonly occurring in the third trimester but sometimes also as soon as the end of the [ncbi.nlm.nih.gov]

Mitochondrial Trifunctional Protein Deficiency

In a small number of cases, HADHA mutations appear to increase a woman's risk of developing two serious liver disorders during pregnancy, known as acute fatty liver of pregnancy [ghr.nlm.nih.gov]

HADHB mutations appear to increase a woman's risk of developing two serious liver disorders during pregnancy, known as acute fatty liver of pregnancy (AFLP) and HELLP syndrome [ghr.nlm.nih.gov]

Acute fatty liver of pregnancy (AFLP) is a devastating disorder of the maternal liver in the third trimester. [ncbi.nlm.nih.gov]

Cholestasis

Obstetric cholestasis (OC), also known as intrahepatic cholestasis of pregnancy (ICP), is a rare liver disorder that affects 0.5% to 2% pregnancies ( 1 ). [momjunction.com]

However, more intense, persistent itchiness could be a symptom of intrahepatic cholestasis of pregnancy (ICP), a group of liver disorders specific to pregnancy that interfere [parents.com]

ICP is a group of liver disorders specific to pregnancy which interfere with the flow of bile. [icpcare.org]

Hepatic Rupture

It occurs in 3% to 10% of all pregnancies. Several disorders contribute to liver disease in pregnancy ( Box 1 ). [clevelandclinicmeded.com]

Spontaneous liver rupture during pregnancy is extremely rare, and often associated with hypertensive disorders. Maternal outcomes are poor and morbidity is high. [ncbi.nlm.nih.gov]

Hepatic laceration is often a fatal complication of trauma, pregnancy, anticoagulant therapy, connective tissue disorders, liver infiltrative diseases, hepatocellular carcinomas [ejournal.tnmed.org]

Benign Gestational Thrombocytopenia

Hypertensive and microangyopathic disorders in pregnancy Preeclampsia, HELLP syndrome (Haemolysis. [medichub.ro]

Coagulation profile, liver function, renal function, screening for autoimmune disorders or hereditary macrothrombopathies. [medichub.ro]

Elevated Liver enzymes, Low Platelets), haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura (TTP) have common aspects and an overlap between them and some [medichub.ro]

Benign Recurrent Intrahepatic Cholestasis Type 1

]: A liver disorder of pregnancy. [genecards.org]

[…] intrahepatic, 1 (PFIC1) and one autosomal dominant disorder: cholestasis, intrahepatic, of pregnancy, 1 (ICP1). [ctgt.net]

Intrahepatic cholestasis of pregnancy Hepatitis (viral and alcoholic) Genetic disorders Graft-versus-host disease Post-liver transplantation Extrahepatic Biliary Tract Diseases [clevelandclinicmeded.com]

Fetal Distress in Labor

a liver disorder during pregnancy Treatment[edit] Instead of referring to "fetal distress", current recommendations hold to look for more specific signs and symptoms, assess [en.wikipedia.org]

a liver disorder that occurs during pregnancy; Obesity; Significant or rapid weight gain during pregnancy. [thecplawyer.com]

[…] births Shoulder dystocia Umbilical cord prolapse Nuchal cord Placental abruption Premature closure of the fetal ductus arteriosus Uterine rupture Intrahepatic cholestasis of pregnancy [en.wikipedia.org]

Bowel Bypass Syndrome

In some women, a blood clotting disorder may first become apparent during pregnancy. [merckmanuals.com]

[…] during pregnancy. [merckmanuals.com]

Other causes include disorders that develop near the hepatic veins, such as parasitic infections and liver tumors or kidney tumors that press on or invade the veins. [merckmanuals.com]

Herpes Gestationis

Common liver disorders in pregnancy are intrahepatic cholestasis of pregnancy, HELLP syndrome (haemolysis, elevated liver enzymes and low platelets), and acute fatty liver [mja.com.au]

[…] and biliary tract disorders in pregnancy, childbirth and the puerperium O26.61 Liver and biliary tract disorders in pregnancy Reimbursement claims with a date of service [icd10data.com]

liver disorders occur in the third trimester; thus, an aetiological diagnosis of liver diseases can be difficult. [mja.com.au]

Congenital Liver Cirrhosis

It occurs in 3% to 10% of all pregnancies. Several disorders contribute to liver disease in pregnancy ( Box 1 ). [clevelandclinicmeded.com]

Acute Fatty Liver of Pregnancy AFLP is a rare disorder of the third trimester, affecting less than 0.01% of pregnant women. [clevelandclinicmeded.com]

Vigilance in recognizing liver disorders in pregnancy and early coordinated management among the primary care physician, obstetrician, liver specialist, and transplant surgeon [clevelandclinicmeded.com]

Pruritic Urticarial Papules and Plaques of Pregnancy

[…] and biliary tract disorders in pregnancy, childbirth and the puerperium O26.61 Liver and biliary tract disorders in pregnancy O26.611 Liver and biliary tract disorders in [icd10coded.com]

(ICP): Rare liver disorder that causes itchy skin. • Impetigo herpetiformis (IH): Causes pustular eruptions. • Viral exanthem: Viral rashes. • Scabies : skin disease spread [womens-health-advice.com]

pregnancy, first trimester O26.612 Liver and biliary tract disorders in pregnancy, second trimester O26.613 Liver and biliary tract disorders in pregnancy, third trimester [icd10coded.com]

Fatty Liver

This disorder, called fatty liver of pregnancy or microvesicular steatosis, is usually considered a different disorder from fatty liver. [merckmanuals.com]

Pregnancy The combination of excess body weight, insulin resistance, and high triglyceride levels is called metabolic syndrome. [msdmanuals.com]

Rarely, fat accumulates in the liver during late pregnancy. [merckmanuals.com]

Ampulla of Vater Obstruction Syndrome

disorder in pregnancy Mirizzi's syndrome Neonatal intrahepatic cholestasis due to citrin deficiency Obstruction of bile duct Obstruction of biliary tree Obstruction of common [icdlist.com]

Other factors that may encourage gallstone formation are: infection anemia obesity intestinal disorders coronary artery disease multiple pregnancies a high-fat, low-fiber [encyclopedia.com]

[…] biliary tract anastomosis Drug-induced intrahepatic cholestasis Extrahepatic cholestasis Extrahepatic obstructive biliary disease GRACILE syndrome Intrahepatic cholestasis Liver [icdlist.com]

Diastasis Symphysis Pubis

O26.4 임신 포진(Herpes gestationis) O26.5 모성 저혈압 증후군(Maternal hypotension syndrome) 앙와위성 저혈압 증후군(Supine hypotensive syndrome) O26.6 임신, 출산 및 산욕기중 간 장애(Liver disorders in pregnancy [dic.impact.pe.kr]

[…] and biliary tract disorders in childbirth O26.63 Liver and biliary tract disorders in the puerperium O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the [icd10data.com]

[…] with current abortion)(O03-006) 현재 임신이 아닌 습관성 유산자(habitual aborter without current pregnancy)(N96) O26.3 임신중 체류된 자궁내 피임 기구(Retained intrauterine contraceptive device in pregnancy [dic.impact.pe.kr]

Hepatic Infarction

Recognition of infarction as a separate entity among the spectrum of the pregnancy-related liver disorders should help avoid unneeded delay in diagnosis or inappropriate treatment [ncbi.nlm.nih.gov]

[…] clotting disorder (one case), haemolytic anaemia, elevated liver enzymes, low platelet count (HELLP) syndrome (one case); eclampsia and disseminated intravascular coagulation [ncbi.nlm.nih.gov]

Pregnancy-related liver diseases are complex in presentation and oftentimes confusing to clinicians, leading to misdiagnoses and unwarranted or delayed therapies. [ncbi.nlm.nih.gov]

Ascending Cholangitis

Intrahepatic cholestasis of pregnancy Intrahepatic cholestasis of pregnancy (ICP) is a potentially serious liver disorder that can develop in pregnancy. [nhs.uk]

Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis (OC), is a liver disorder that can develop during pregnancy. [tommys.org]

Intrahepatic cholestasis of pregnancy is a liver disorder that occurs in pregnant women. [ghr.nlm.nih.gov]

Hereditary Thyroxine-Binding Globulin Deficiency

An increased TBG level may be due to: Acute intermittent porphyria (a rare metabolic disorder) Hypothyroidism (underactive thyroid) Liver disease Pregnancy (TBG levels normally [medlineplus.gov]

In other cases, high TBG levels may be due to liver disease, a rare genetic blood disorder called “acute intermittent porphyria,” or hypothyroidism, which occurs when your [healthline.com]

Decreased TBG levels may be due to: Acute illness Acromegaly (disorder caused by too much growth hormone) Hyperthyroidism (overactive thyroid) Malnutrition Nephrotic syndrome [medlineplus.gov]

Solitary Renal Cyst

[…] in liver disease MURRAY EPSTEIN 477 Renal complications of pregnancy JOHN M DAVISON ADRIAN I KATZ AND MARSHALL D LINDHEIMER 495 494 Diabetic nephropathy ELIA FRIEDMAN 533 [books.google.com]

Renal cystic disorders JARED J GRANTHAM JOANN B RECKLING AND SHARON L SLUSHER 543 Renal disorders in sickle hemoglobinemia STEPHANIE LEAR AND ROBERT M ROSA 573 Inherited [books.google.com]

LIEBERMAN 443 442 Renal involvement in dysproteinemias DOMINIQUE GANEVAL AND JEANPIERRE GRUNFELD 453 Hyperuricemic nephropathy EDWARD R AHRENS AND THOMAS H STEELE 469 Renal disorders [books.google.com]

Alcoholic Fatty Liver

This disorder, called fatty liver of pregnancy or microvesicular steatosis, is usually considered a different disorder from fatty liver. [merckmanuals.com]

Rarely, fat accumulates in the liver during late pregnancy. [merckmanuals.com]

As a result, fat accumulates and is then stored inside liver cells. Just consuming a high-fat diet does not result in fatty liver. [merckmanuals.com]

Pruritic Rash

disorder unique to pregnancy. 9 Unrelenting pruritus, abnormal liver function tests in the absence of viral or drug-induced hepatitis, and elevated serum cholic acid are [aafp.org]

[…] used interchangeably in the literature. 1 ICP, also called obstetric cholestasis, 8 usually presents in the third rather than the first trimester and is the most common liver [aafp.org]

Dubin-Johnson Syndrome

Dubin-Johnson syndrome and intrahepatic cholestasis of pregnancy are rare chronic liver disorders. [ncbi.nlm.nih.gov]

Abstract : Background: Dubin–Johnson syndrome and intrahepatic cholestasis of pregnancy are rare chronic liver disorders. [hal.inserm.fr]

People with DJS have lifelong mild jaundice that may be made worse by: Alcohol Birth control pills Environmental factors that affect the liver Infection Pregnancy Definition [account.allinahealth.org]