Liver Enzymes Abnormal: Causes & Reasons

Possible Causes for Liver Enzymes Abnormal

To our best knowledge, this is the first report of a puerperal woman with hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome in whom color vision abnormality [ncbi.nlm.nih.gov]

We report a post-partum woman with PRES associated with hemolysis, elevated liver enzymes, and low platelets syndrome (HELLP), in whom color vision abnormality (achromatopsia [ncbi.nlm.nih.gov]

Hypertension-induced hepatic disease is a common cause of abdominal pain and liver function test abnormalities in the pregnant patient. [ncbi.nlm.nih.gov]

Hemochromatosis

The disease is usually diagnosed as a result of family screening or after a blood test indicates a high level of iron or abnormal liver enzymes. [hopkinsmedicine.org]

diabetes, enlarged heart or abnormal laboratory results with high liver enzymes. [ihtc.org]

Patients most commonly present with nonspecific symptoms such as unexplained chronic fatigue (tiredness), weakness, joint pain or stiffness, sexual dysfunction, enlarged liver [ihtc.org]

Glycogen Storage Disease

[…] manifestations are similar to von Gierke's disease but glycogen is abnormal.  Moderate hypoglycemia. 8.  Enzyme deficiency:  Glucosyl 4-6 transferase (branching enzyme [slideshare.net]

Glycogen storage disease type 3 is a rare inherited disorder resulting from a deficiency of the glycogen debranching enzyme, causing the accumulation of abnormal short-chain [ncbi.nlm.nih.gov]

Diagnostic methods The diagnosis is based on biological findings, revealing increased amounts of abnormal glycogen and enzyme deficiency (1 to 33% residual activity) in a [orpha.net]

Alpha-1 Antitrypsin Deficiency

Taking alpha-1 antitrypsin does not treat or prevent liver damage because liver damage is caused by production of an abnormal enzyme, not by enzyme deficiency. [msdmanuals.com]

Nevertheless, careful surveillance has revealed that many of these have persistently abnormal liver enzyme levels. [clevelandclinicmeded.com]

The most common problems caused by the deficiency are Liver damage If the enzyme is structurally abnormal, it may clump in the liver, causing the liver to malfunction. [msdmanuals.com]

Acute Fatty Liver of Pregnancy

[…] failure with hepatic encephalopathy Blood tests showing severely abnormal liver enzymes help making the diagnosis. [babymed.com]

Children with this deficiency have hypoglycemia, coma, and abnormal liver enzymes or sudden death which cannot find the cause. [hellodoktor.com]

The lab tests show abnormalities such as elevated liver enzymes, hypoglycemia, elevated white blood cell count and decreased fibrinogen. [ic.steadyhealth.com]

Preeclampsia

HELLP syndrome, a severe variant of preeclampsia, may be diagnosed with high levels of liver enzymes or abnormal blood platelet measurements. [healthywomen.org]

liver enzymes Low platelet count Oliguria (low urine output) less than 500ml per 24 hours Impaired kidney or liver functions MANAGEMENT AND TREATMENT There is no cure for [healthyslide.com]

Urine and blood tests can also show protein in your urine, abnormal liver enzymes, and low platelet levels. [healthline.com]

Cholelithiasis

Usually have abnormalities in liver enzymes and pain but no fever. The 2 major complications are 1) Cholangitis and 2) Acute pancreatitis. [sketchymedicine.com]

The diagnosis should be suspected in patients with fever, elevated inflammatory markers, and jaundice or abnormal liver enzymes. [amboss.com]

Viral Hepatitis

In renal transplant recipients on long-term immunosuppression therapy, particularly AZA, it is prudent to maintain a high index of suspicion for HCC when liver enzyme level [ncbi.nlm.nih.gov]

Acute viral hepatitis refers to inflammation of the liver associated with symptoms and abnormalities of liver enzymes, which last for a period less than six months. [gi.org]

[…] or function abnormalities are encountered. [ncbi.nlm.nih.gov]

Toxic Shock Syndrome

An elevated white blood cell count, elevated liver enzymes, abnormal electrolytes, and abnormal kidney function may be consistent with toxic shock syndrome. [emedicinehealth.com]

If the doctor suspects toxic shock syndrome, the following tests are usually performed: Blood is drawn to check blood counts, electrolytes, and liver and kidney functions. [emedicinehealth.com]

Autoimmune Hepatitis

A 61-year-old male was referred to our hospital because of abnormal liver enzyme levels after initial diagnosis of CAEBV had been made by laboratory tests and liver biopsy [ncbi.nlm.nih.gov]

Liver Enzymes Learn about the importance of testing liver enzyme levels and causes of abnormal levels. Lab Tests What they are and what they mean. [hepatitiscentral.com]

Liver Enzyme Abnormalities Elevation of liver transaminases less than 500 UI/L with normal alkaline phosphatase is typical. [clevelandclinicmeded.com]

Infectious Mononucleosis

[…] panel to see if liver enzymes are abnormal. [encyclopedia.com]

[…] platelets Proteins/enzymes indicative of atypical liver function What is the treatment for EBV infection? [americanpregnancy.org]

Liver function tests. On average, 80% of patients with infectious mononucleosis have abnormal liver function during the early stages of infection (Table 1 ). [doi.org]

Gaucher Disease

This therapy can help reduce abnormalities in the bone, decrease liver and spleen size and reverse some abnormal blood counts. [uvahealth.com]

Treatment Enzyme replacement treatment given intravenously every two weeks can dramatically decrease liver and spleen size, reduce skeletal abnormalities, and reverse other [geneticdiseasefoundation.org]

Gaucher Disease [GBA]: Enlargement of spleen and liver, blood abnormalities (anemia, easy bruising, impaired clotting, etc), and bone problems (joint pain, bone fractures, [jewishgeneticdiseases.org]

Celiac Disease

However, many patients now present with non-classical (atypical) symptoms including anemia, osteoporosis, extreme fatigue, oral ulcers, liver enzyme abnormalities, constipation [celiac.ca]

enzyme abnormalities Someone with celiac disease may have a variety of the above symptoms, and different people with celiac disease may have completely different symptoms [patients.gi.org]

calcium and folate Bone and joint pains Osteoporosis (bone thinning) A skin rash that lasts Infertility or reproductive difficulties Neurological deficits (neuropathy) Liver [patients.gi.org]

Eclampsia

liver enzymes (ALT or AST >70 IU/L). [patient.info]

These include: Abnormal blood test (specifically elevated liver enzymes and low platelet count) Headaches Very high blood pressure (anything over 140/90 is considered a hypertensive [study.com]

Abnormal liver enzymes (ALT or AST rising to above 70 IU/L). Clonus. HELLP syndrome : H aemolysis, E levated L iver enzymes, L ow P latelets. Papilloedema. [patient.info]

Liver Failure

This includes abnormal liver enzymes, nonalcoholic fatty liver disease (NAFLD), cirrhosis, hepatocellular carcinoma, and acute liver failure. [care.diabetesjournals.org]

These tests measure the levels of specific enzymes, bilirubin, and protein that are abnormal when liver injury is present. [labtestsonline.org]

Abnormal liver enzymes Elevation of serum alanine aminotransferase (ALT), while uncommon (0.5%) in apparently normal subjects ( 7 ), is common in patients with type 2 diabetes [care.diabetesjournals.org]

Adult-Onset Still Disease

liver enzymes (mostly ALT, AST, LDH) •Negative ΑΝΑ and RF Conclusion The triad of high fever, evanescent rash and arthralgias or arthritis in a young adult patient, especially [oapublishinglondon.com]

Lymphadenopathy, splenomegaly, and hepatomegaly are detected in 63, 52, and 42% of patients respectively. [3], [4] Close to 75% of patients have elevated liver enzymes. [ijnm.in]

[…] including leucocytosis, high serum ferritin levels and elevated liver enzymes. [doi.org]

Sarcoidosis

(ACE) levels and/or elevated serum lysozyme Chest radiograph revealing BHL Abnormal liver enzyme tests Chest CT scan in patients with a negative chest radiograph result Ocular [emedicine.medscape.com]

right-sided abdominal discomfort and mild elevation in liver enzymes Spleen: left-sided abdominal discomfort and anemia or other blood abnormalities Central nervous system [verywellhealth.com]

liver function that often accompany sarcoidosis. [medicinenet.com]

Budd-Chiari Syndrome

Results from liver enzymes and function tests were abnormal: a total serum bilirubin level of 55 (normal range 1.7 to 20) μmol/L, aspartate aminotransferase level of 130 [cmaj.ca]

Blood tests will often be abnormal, indicating elevated liver enzymes and liver disease. Doctors may initially mistake Budd-Chiari syndrome for cirrhosis. [diagnose-me.com]

Abnormal results of evaluative liver function tests may also indicate BCS. [puristat.com]

Malignant Neoplasm of the Liver

Major complications of this study cases were 12 cases of elevated serum liver enzyme level, 4 cases of clotting abnormality, 2 cases of pleural effusion, 1 case of postoperative [ndsl.kr]

Several chemotherapeutic agents can cause liver toxicity of varying degree ranging from mild transient elevation of liver enzymes to severe or even fatal hepatic failure. [esmoopen.bmj.com]

184, 212–214 The liver itself is fundamentally important in drug metabolism (ie, activation, inactivation, excretion) and patients with abnormal drug metabolism have an increased [esmoopen.bmj.com]

Biliary Atresia

Diagnosis is often made following investigation of prolonged jaundice that is resistant to phototherapy and/or exchange transfusions and abnormalities in liver enzymes tests [checkorphan.org]

Diagnosis is often made following investigation of prolonged jaundice that is resistant to phototherapy and/or exchange transfusions, with abnormalities in liver enzyme tests [en.wikipedia.org]

Diagnosis - Biliary atresia Diagnosis is made by assessing an individual's symptoms, physical exam, and medical history, in conjunction with blood tests, a liver biopsy and [checkorphan.org]

Citrullinemia Type 2

Patients with type II have an abnormality of hepatic argininosuccinate synthetase only, and liver biopsy uniformly shows liver steatosis. [accessanesthesiology.mhmedical.com]

Urea cycle enzyme disorders are liver based metabolic disorders and liver transplantation is, therefore, an ideal treatment. [jnnp.bmj.com]

enzymes 0002910 Fluctuations in consciousness 0007159 Hallucinations Hallucination Sensory hallucination [ more ] 0000738 Hepatomegaly Enlarged liver 0002240 Hypertriglyceridemia [rarediseases.info.nih.gov]

Thrombotic Thrombocytopenic Purpura

enzymes and low platelet count syndrome in pregnancy. [ncbi.nlm.nih.gov]

enzymes low platelet count syndrome), the fetus extraction does not correct TTP symptoms; as a consequence, provided there are no fetal abnormalities, the pregnancy should [doi.org]

The most common cause is disseminated intravascular coagulation, which may be differentiated by abnormal coagulation. [ncbi.nlm.nih.gov]

Human Granulocytic Ehrlichiosis

Moderate elevations of liver enzymes may occur in all three tick-borne infections. [ncbi.nlm.nih.gov]

Ten days later, on September 25, the patient became febrile, which was associated with an elevated C-reactive protein level and mild abnormalities in liver enzyme levels, [elbiruniblogspotcom.blogspot.com]

Both infections may present with routine laboratory abnormalities, including leukopenia and/or thrombocytopenia in HGE and anemia in babesiosis. [ncbi.nlm.nih.gov]

Leptospirosis

Liver tests ( ALT, GGT, bilirubin ) are commonly abnormal. Alkaline phosphatase ( AP ) – an enzyme released by many injured tissues is often elevated. [2ndchance.info]

Q Fever

The most common laboratory abnormalities are increased liver enzyme levels, which are observed in up to 85% of cases ( 89 ). [cdc.gov]

Liver Phosphorylase Kinase Deficiency

The liver can become irritated or inflamed from storing increased amounts of glycogen, which can cause some blood tests to be abnormal with elevated enzymes (ALT and AST) [agsdus.org]

Type IV (Branching Enzyme deficiency)-Andersons disease of Amylopectinosis It is extremely rare disorder manifested by production of an abnormal form of unbranched glycogen [edusanjalbiochemist.blogspot.com]

In some cases, liver transplantation may abolish biochemical abnormalities. Active research continues. [usmle.biochemistryformedics.com]

Congenital Disorder of Glycosylation Type 1T

with elevated liver enzymes abnormal bleeding or blood clotting misaligned or crossed eyes (strabismus) seizures stroke-like episodes heart problems, including fluid accumulation [chop.edu]

[…] in abnormal storage of glycogen in the liver and various muscles. [sjhbangorlab.testcatalog.org]

resulting in an accumulation of abnormal GLYCOGEN with long outer branches. [ncbi.nlm.nih.gov]

3Beta-Hydroxy-Delta5-C27-Steroid Oxidoreductase Deficiency

[…] jaundice, enlarged liver, abnormal liver enzyme tests), steatorrhea, or complications from decreased fat soluble vitamin absorption; and Cholic acid (Cholbam) is being used [aetna.com]

A low level of sulphation of the abnormal trihydroxy bile acid formed as a result of enzyme deficiency may be of importance for survival. [onlinelibrary.wiley.com]

Peroxisomal disorder (PD) The member has a documented diagnosis of a peroxisomal disorder (see Appendix 2 ); and The member exhibits manifestations of liver disease (e.g. [aetna.com]

Non-Alcoholic Fatty Liver Disease

BACKGROUND AND AIM: The association between obstructive sleep apnea (OSA) and abnormal liver enzymes has been reported in multiple studies. [ncbi.nlm.nih.gov]

A 33-year-old male with an insulinoma, who had been hypoglycemic during the previous four years, developed abnormally elevated levels of liver enzymes and histological fatty [ncbi.nlm.nih.gov]

When liver enzymes are elevated the most common laboratory abnormalities are elevations in aminotransferase levels. [msdmanuals.com]

Chronic Alcoholism

Of five chronic alcoholics with acute skeletal muscle necrosis (rhabdomyolysis) three developed acute heart failure with disturbances of rhythm and conduction. Symptoms came on abruptly after a period of intensified drinking. Myocardial infarction, thiamine deficiency, and cobalt intoxication were excluded. Probably[…] [ncbi.nlm.nih.gov]