Liver Fibrosis Causes & Reasons

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Liver Fibrosis Symptom Checker: Possible causes include Liver Cirrhosis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Liver Fibrosis,

Negated

None

Unsure

None

Possible Causes

Liver Cirrhosis

Keywords: Liver fibrosis, Cirrhosis, Regression, Hepatic repair complex INTRODUCTION Fibrosis is an integral component of chronic liver disease. [ncbi.nlm.nih.gov]

liver fibrosis. [ncbi.nlm.nih.gov]

Non-invasive markers associated with liver fibrosis in non-alcoholic fatty liver disease. [ncbi.nlm.nih.gov]

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Alcoholic Liver Disease

Three different testing alternatives were studied: a single liver biopsy; annual Enhanced liver fibrosis (ELF ) followed by liver stiffness measurement (LSM) imaging as a [ncbi.nlm.nih.gov]

Chronic alcohol abuse leads to liver damage, liver inflammation, fibrosis and hepatocellular carcinoma. [ncbi.nlm.nih.gov]

CONCLUSIONS: TE has excellent diagnostic value for liver fibrosis in alcoholic liver disease. [ncbi.nlm.nih.gov]

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Systemic Scleroderma

[…] in idiopathic or radiation induced pulmonary fibrosis, liver fibrosis from viruses or toxins, kidney fibrosis from diabetes and other less common kidney diseases, and heart [sciencedaily.com]

fibrosis. [en.wikipedia.org]

[…] researchers proving that TGF-beta can block scarring may provide a major treatment advance for scarring-mediated organ dysfunction common to many diseases including lung fibrosis [sciencedaily.com]

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Portal Cirrhosis

Clinical findings Ascites, increased infections including pneumonia, poor self-care, hepatic encephalopathy, liver fibrosis leading to portal hypertension, and oesophageal [medical-dictionary.thefreedictionary.com]

[…] of liver fibrosis that leads to shunting of the portal and arterial blood supply directly into hepatic outflow through the central veins with compromised exchange between [accesspharmacy.mhmedical.com]

Very recently, two studies showed in two different models of NAFLD that liver endothelial dysfunction develops in the absence of fibrosis and inflammation in the fatty liver [elsevier.es]

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Macronodular Cirrhosis

Liver biopsy is necessary for diagnosis and staging of liver fibrosis. [pubs.rsna.org]

[…] and stage 3 liver fibrosis. [ncbi.nlm.nih.gov]

Next Steps Evidence Creator Insights Advice Low fibrosis scores may be appropriate candidates for medical management and may not require liver biopsy if FIB-4 scores continue [mdcalc.com]

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Fatty Liver

fibrosis in nonalcoholic fatty liver disease. [ncbi.nlm.nih.gov]

If untreated, liver fibrosis may progress to cirrhosis of the liver, liver failure, and liver cancer. [radiologyinfo.org]

Wong VW, Vergniol J, Wong GL et al (2010) Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. [doi.org]

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Cryptogenic Cirrhosis

Therefore, our aim was to assess recurrence of liver fibrosis in patients transplanted for NASH versus CC after OLT. [ncbi.nlm.nih.gov]

1 Lysosomal acid lipase activity and liver fibrosis in the clinical continuum of non-alcoholic fatty liver disease. 61 31392821 2019 2 Metastatic cholangiocarcinoma in a patient [malacards.org]

The scar tissue forms fibrous masses (a condition called liver fibrosis ) and, over time, causes degradation of liver function eventually leading to complete liver failure [liverbasics.com]

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Congenital Hepatic Fibrosis

Key words: liver fibrosis, living donor liver transplantation, congenital hepatic fibrosis, chronic liver failure [scopemed.org]

RESULTS: Congenital hepatic fibrosis liver tissue homogenates had higher levels of thrombospondin-1 and transforming growth factor-beta1 protein than in normal livers. [ncbi.nlm.nih.gov]

Liver fibrosis is a wound healing response in which collagen accumulates in the liver due to an imbalance between extracellular matrix synthesis and degradation. [ncbi.nlm.nih.gov]

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Niemann-Pick Disease Type B

Biopsies were evaluated for fibrosis, SM accumulation, and macrophage infiltration by light and electron microscopy. [ncbi.nlm.nih.gov]

[…] and skin pathology Liver fibrosis in almost all patients. [ojrd.biomedcentral.com]

In the liver, the infiltration of foamy cells and ballooning of hepatocytes can lead to various degrees of hepatic fibrosis. [radiopaedia.org]

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Chronic Hepatitis C

fibrosis and was more useful for to predict all liver fibrosis grades in HCV patients than liver fibrosis biomarkers. 2018 Wiley Periodicals, Inc. [ncbi.nlm.nih.gov]

[…] and the stages of liver fibrosis (r 0.026, p 0.923). [ncbi.nlm.nih.gov]

Liver fibrosis was assessed by transient elastography. [ncbi.nlm.nih.gov]

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Hepatopathy

If untreated, liver fibrosis may progress to cirrhosis of the liver, liver failure, and liver cancer. [radiologyinfo.org]

[…] and stage 3 liver fibrosis. [ncbi.nlm.nih.gov]

[…] as liver fibrosis. [ncbi.nlm.nih.gov]

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Hemochromatosis

METHODS: Liver fibrosis was histologically assessed by Ishak score. [ncbi.nlm.nih.gov]

BACKGROUND AND AIMS: In hereditary hemochromatosis, iron deposition in the liver parenchyma may lead to fibrosis, cirrhosis and hepatocellular carcinoma. [ncbi.nlm.nih.gov]

CONCLUSIONS: Our findings indicate that GNPAT rs11558492 is not a major modifier of iron status and is not associated with liver fibrosis in HFE-HH patients. [ncbi.nlm.nih.gov]

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Chronic Liver Disease

fibrosis in HCV-associated chronic liver disease (HCV-CLD). 145 Egyptian HCV-CLD patients were divided according to Metavir fibrosis scores. [ncbi.nlm.nih.gov]

These findings indicate that PlGF plays an important role in liver fibrosis-associated angiogenesis and that blockage of PlGF could be an effective strategy for chronic liver [ncbi.nlm.nih.gov]

BACKGROUND/PURPOSE: Metabolic risk factors are associated with liver fibrosis. [ncbi.nlm.nih.gov]

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Liver Fibrosis

Abstract Liver fibrosis is a wound-healing response generated against an insult to the liver that causes liver injury. [ncbi.nlm.nih.gov]

Thus, noninvasive methods for assessing liver fibrosis are of great clinical interest. [ncbi.nlm.nih.gov]

A severe degree of liver fibrosis, almost corresponding to cirrhosis, was observed in liver biopsy material obtained from a boy with this disorder. [ncbi.nlm.nih.gov]

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Alcoholic Fatty Liver

• Liver fat content is positively correlated with EAT. • Liver fat content and liver fibrosis were independently associated with EAT. • Higher liver fat content and fibrosis [ncbi.nlm.nih.gov]

Wong VW, Vergniol J, Wong GL et al (2010) Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. [doi.org]

This inhibition in gene expression was associated with a lowering of liver fibrosis and hepatocellular injury. [ncbi.nlm.nih.gov]

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Congenital Liver Cirrhosis

His lecture titled "Mechanisms of the Progression and Regression of Liver Fibrosis" provided important advice for developing antifibrotic agents. [books.google.de]

One such organ is the liver, in which fibrosis develops in response to elevated pressure within the veins. [sciencedaily.com]

The Ishak liver fibrosis score was downgraded to 1 compared to 3 before the procedures ( Figures 3,4 ). [sci.amegroups.com]

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Primary Sclerosing Cholangitis

Enhanced liver fibrosis (ELF) test was previously reported to predict outcome in PSC. [ncbi.nlm.nih.gov]

The progression of liver fibrosis in an individual patient is difficult to predict and may vary from a relatively benign, nonprogressive form to a rapidly progressive form [ncbi.nlm.nih.gov]

INTRODUCTION: Primary sclerosing cholangitis (PSC) is a progressive inflammatory liver disease characterised by relentless liver fibrosis and a high unmet need for new therapies [ncbi.nlm.nih.gov]

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Cardiac Cirrhosis

[…] injury is usually self-limiting when it affects the normal liver, but more serious changes may occur when the liver has been previously damaged 10 Congestive liver fibrosis [powershow.com]

The serum 7S domain of collagen type IV (P4NP 7S) is an established marker of liver fibrosis in chronic liver disease. [pubfacts.com]

For the remainder of this chapter, the term cardiac cirrhosis will be used to mean congestive hepatopathy with or without liver fibrosis. Cardiac cirrhosis. [emedicine.medscape.com]

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Chronic Hepatitis

BACKGROUND: Evaluation of liver fibrosis is important to assess prognosis and guide the treatment for chronic hepatitis B. [ncbi.nlm.nih.gov]

Significant liver fibrosis was found in 24/70 patients. [ncbi.nlm.nih.gov]

Serum YKL-40 is a feasible biomarker of liver fibrosis in chronic hepatitis B patients. [ncbi.nlm.nih.gov]

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Cholesterol Ester Storage Disease

In detail, CESD causes liver enlargement, possibly followed by liver fibrosis and cirrhosis, and atherosclerosis, which predisposes for coronary heart disease and stroke. [symptoma.com]

Late onset – sometimes called Cholesteryl Ester Storage Disease (CESD), affects 25 individuals per million births and may lead to liver fibrosis, cirrhosis, liver failure [cuh.nhs.uk]

fibrosis, cirrhosis, liver failure and death. [cuh.nhs.uk]

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Senior-Løken Syndrome

We present two sisters with nephronophthisis and pigmentary retinopathy (Senior-Loken syndrome) and associated liver fibrosis. [ncbi.nlm.nih.gov]

Our report underlines the need to investigate liver disorders in all patients with nephronophthisis and the existence of liver fibrosis as an element of the hereditary ‘nephronophthisis [karger.com]

Systemic associations of this syndrome include sensorineural hearing loss, liver fibrosis or cerebral vermis hypoplasia. [ncbi.nlm.nih.gov]

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Portal Hypertension

[…] and spleen stiffness measurement (LSM and SSM) with SSI for the detection of liver fibrosis, portal hypertension, and gastroesophageal varices in liver diseases. [ncbi.nlm.nih.gov]

AIMS: To evaluate the diagnostic efficacy of noninvasive liver fibrosis indexes in the diagnosis of PH. [ncbi.nlm.nih.gov]

fibrosis, HSC phenotype and liver inflammation. [ncbi.nlm.nih.gov]

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Hepatitis C

KEYWORDS: HCV genotype; Hepatitis C virus (HCV); advanced liver fibrosis; adverse event; antiviral regimen; case reports; cirrhosis; dasabuvir; decreased kidney function; [ncbi.nlm.nih.gov]

12 to 24 weeks, depending on degree of liver fibrosis and history of prior treatment Simeprevir can cause anemia and photosensitivity. [msdmanuals.com]

Those with a lesser degree of liver fibrosis typically are not at increased risk for developing liver cancer. [newsnetwork.mayoclinic.org]

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Presinusoidal Portal Hypertension

“Noncirrhotic Presinusoidal Portal Hypertension Is Common in Cystic Fibrosis-associated Liver Disease.” Hepatology 53 (3): 1064–1065. [biblio.ugent.be]

ITEM METADATA RECORD Title: Noncirrhotic presinusoidal portal hypertension is common in cystic fibrosis-associated liver disease Authors: Witters, Peter Libbrecht, Louis Roskams [lirias.kuleuven.be]

However, the patient had a PLB one month prior to the onset of symptoms, with F2 liver fibrosis. [elsevier.es]

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Chronic Hepatic Schistosomiasis

Inducible nitric oxide synthase expression (iNOS) in chronic viral hepatitis and its correlation with liver fibrosis. [pacificejournals.com]

Young patient with severe liver fibrosis and portal hypertension. [atlasofscience.org]

Chronic infection can also lead to increased risk of liver fibrosis or bladder cancer. [cdc.gov]

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Glycogen Storage Disease Type 9

In the patients described here, this genotype is associated with development of liver fibrosis. [ncbi.nlm.nih.gov]

Therefore, defect in PHKG2 should be considered in patients with suspected glycogenosis associated with significant liver fibrosis and cirrhosis. [ncbi.nlm.nih.gov]

Conditions such as renal tubular acidosis, splenomegaly, liver fibrosis and cirrhosis, and polycystic ovary syndrome have been described. [symptoma.com]

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Primary Biliary Cirrhosis

The diagnostic value of LS and the four indicators of liver fibrosis in determining liver cirrhosis degree with PBC, whether used alone or in combination, were analyzed by [ncbi.nlm.nih.gov]

Additionally, MRI using diffusion-weighted imaging with apparent diffusion coefficient measurements provides non-invasive assessment of the stage of liver fibrosis. [ncbi.nlm.nih.gov]

These results highlight the important role of liver fibrosis in hepatocarcinogenesis in patients with PBC. [ncbi.nlm.nih.gov]

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Biliary Atresia

fibrosis by comparing it with liver fibrosis biopsy pathology. [ncbi.nlm.nih.gov]

The downregulation of miR-145 may contribute to liver fibrosis in BA by upregulating the expression of ADD3. [ncbi.nlm.nih.gov]

Liver biopsies were scored for fibrosis and tested for association with clinical biochemical characteristics. [ncbi.nlm.nih.gov]

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Passive Congestion of the Liver

For the remainder of this chapter, the term cardiac cirrhosis will be used to mean congestive hepatopathy with or without liver fibrosis. Cardiac cirrhosis. [emedicine.medscape.com]

The pattern of fibrosis is different from cirrhosis due to alcoholic liver disease, since fibrosis in that condition bridges from portal to portal. [uaz.edu.mx]

[…] cirrhosis (of liver) ( K70.3 ) alcoholic fibrosis of liver ( K70.2 ) cardiac sclerosis of liver ( K76.1 ) cirrhosis (of liver) with toxic liver disease ( K71.7 ) congenital [icd10data.com]

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Meckel Syndrome

We present a male fetus with meningoencephalocele, multicystic renal dysplasia, congenital liver fibrosis, and other anomalies. [ncbi.nlm.nih.gov]

Other defects may also be taken into consideration during the diagnostic process, such as liver fibrosis. [symptoma.com]

fibrosis and pulmonary hypoplasia. [medical-genetics.de]

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