Liver Function Impairment: Causes & Reasons

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Possible Causes for Liver Function Impairment

Mitochondrial Complex 3 Deficiency Nuclear Type 1

function Absent speech Glutaric aciduria Apathy Pigmentary retinopathy Neurological speech impairment Respiratory insufficiency Flexion contracture Scoliosis Feeding difficulties [mendelian.co]

Blindness Mental deterioration Leukodystrophy Delayed speech and language development Decreased activity of the pyruvate dehydrogenase complex Abnormality of movement Decreased liver [mendelian.co]

Lambert-Eaton Syndrome

Guanidine, a drug that increases the release of acetylcholine, often lessens symptoms but may inhibit the bone marrow’s production of blood cells and impair liver function [merckmanuals.com]

Ornithine Transcarbamylase Deficiency

Some UCD patients have undergone liver transplantation due to the severe impairment of liver function during their first metabolic crisis, and before the diagnosis was definitively [journals.plos.org]

Mitochondrial abnormalities within the liver of patients with OTCD has been previously demonstrated[15], and hyperammonemia itself disrupts the function of mitochondria[16 [wjgnet.com]

In ALF associated with metabolic diseases, there is a lack of consensus criteria for liver transplantation [ 12 ]. [journals.plos.org]

Visceral Leishmaniasis

If visceral leishmaniasis progresses, it attacks the immune system and affects the bone marrow and internal organs (including enlargement and impaired function of the spleen [unitingtocombatntds.org]

[…] and liver), as well as causing irregular bouts of fever, substantial weight loss and anaemia. [unitingtocombatntds.org]

Selenosis

When glutathione production is low, detoxification in the liver is seriously impaired. [drlwilson.com]

Thus, this function of selenium is also a critical one. 3. Heavy metal detoxification. [drlwilson.com]

Cadmium Poisoning

In addition, like nickel, cadmium can replace zinc in critical metabolic pathways, impairing immune system function. [coreonehealth.com]

Levels of other fats may be adversely affected if liver function is impaired by cadmium toxicity. [arltma.com]

Increased exposures to cadmium damages the liver and kidneys, softens bone, and even causes a loss of sense of smell. [coreonehealth.com]

Venous Air Embolism

Anesth Analg. 2005 Oct;101(4):966-70, table of contents. Author information 1 Department of Anesthesia and Pain Medicine, Yonsei University College of Medicine, 134 Shinchon-Dong, Seodaemun-Gu, C.P.O. Box 8044, Seoul 120-752, Korea. koobn@yumc.yonsei.ac.kr Abstract The Cavitron Ultrasonic Surgical Aspirator (CUSA) is an[…] [ncbi.nlm.nih.gov]

Staphylococcus Aureus Infection

Result Filters Abstract Staphylococcus aureus strains that produce Panton-Valentine leukocidin are known to cause community infections. We describe an outbreak of skin abscesses caused by Panton-Valentine leukocidin-producing methicillin-susceptible S. aureus (clonal complex 121) in a professional rugby team in[…] [ncbi.nlm.nih.gov]

Clostridium Perfringens Infection

Chlorphenol Poisoning

liver functional state. [pubmed.ncbi.nlm.nih.gov]

[…] aminotransferase, aspartate aminotransferase) and cholestasis (alkaline phosphatase), intensified lipid peroxidation, depressed activity of antioxidant enzymes (catalase), impaired [pubmed.ncbi.nlm.nih.gov]

Toxic Liver Disease

In hepatic encephalopathy, toxins are not removed because liver function is impaired. [merckmanuals.com]

Isn’t Functioning Optimally If you have recently noticed any of the symptoms listed below, you could be suffering from impaired liver function. [draxe.com]

However, it is a condition that requires attention and investigation may determine impairment of liver function to be a contributing factor. [globalhealingcenter.com]

Aggressive Systemic Mastocytosis

Respective clinical findings (so called C-Findings) include cytopenias, osteolysis (or osteoporosis) with pathologic fractures, hepatosplenomegaly with impaired liver function [ncbi.nlm.nih.gov]

[…] of liver function as becomes evident from portal hypertension or ascites Palpable splenomegaly is detected and is associated with hypersplenism Patients suffer pathological [symptoma.com]

The organ-systems most frequently affected are the bone marrow, skeletal system, liver, spleen, and the gastrointestinal tract. [ncbi.nlm.nih.gov]

Autosomal Dominant Alport Syndrome

We have mapped the disease-causing gene to the long arm of chromosome 22 in an extended Israeli family with Fechtner syndrome plus impaired liver functions and hypercholesterolemia [ncbi.nlm.nih.gov]

Ornithine Aspartate Poisoning

If liver function is substantially impaired, the infusion rate must be adjusted to individual patient in order to prevent nausea and vomiting. [mims.com]

Portal Cirrhosis

liver function): Impaired protein synthesis (leukonychia [white nails], ascites, bruising) Impaired biliary excretion (jaundice, pruritus) Impaired nitrogen metabolism (hepatic [pathologyoutlines.com]

[…] of liver function, and ultimately producing the typical hobnail liver — called also portal cirrhosis Learn More about Laennec's cirrhosis Cite this Entry “Laennec's cirrhosis [merriam-webster.com]

Subsequent hepatic repair mechanisms lead to fibrosis and abnormal tissue architecture, which impair liver function. [amboss.com]

Cobalt Poisoning

Necrosis at high levels of Cr (VI) Kidney Co excreted by the liver Can impair liver function Respiratory System Asthma Shortness of breath Asthma Shortness of breath Nervous [mjalterlaw.com]

Symptoms of Chromium poisoning may include: Acute renal failure GI hemorrhage Impaired liver function Increased risk of cancers Legal Rights For DePuy Patients With Chromium [nursinghomelawcenter.org]

[…] expression Cr (VI) Localized tissue around the implant Hypersensitivity Inflammation Infiltration of lymphocytes Hypersensitivity Inflammation Infiltration of lymphocytes Liver [mjalterlaw.com]

Cardiac Cirrhosis

[…] non alcoholic liver disease accumulation of fat in the liver cells which eventually lead to formation of fibrous tissues and impaired liver function cirrhosis characterized [quizlet.com]

Impaired liver function. Failure in uptake or conjugation. Deficiencies in uptake are uncommon and are generally due to genetic disorders. [mediktor.com]

Macronodular Cirrhosis

Impaired liver function. Hepatic failure. Hepatocellular carcinoma. [brainscape.com]

liver function. [icdlist.com]

Liver Cirrhosis

Alcoholism and impaired liver function are important predictors of the presence of spider angiomas in patients with liver cirrhosis. [ncbi.nlm.nih.gov]

Given the patient's impaired liver function because of his liver disease conservative treatment was initiated with an inner-outer drain under transparietal hepatic cholangiography [ncbi.nlm.nih.gov]

The liver becomes granular and nodular, and the iron particles may be so dense as to impair liver cell function. [britannica.com]

Spider Naevus

"Spider angiomas in patients with liver cirrhosis: role of alcoholism and impaired liver function". Scand. J. [en.wikipedia.org]

[Facial skin lesions in male patients with liver cirrhosis: role of serum sex hormones and correlation with impaired liver function]. [termedia.pl]

Spider angiomas in patients with liver cirrhosis: role of alcoholism and impaired liver function. Scand J Gastroenterol 1999; 34: 520-3 9. Iino S. [jpgmonline.com]

Chronic Hepatopathy

English Micafungin treatment should be conducted on a careful risk/benefit basis, particularly in patients having severe liver function impairment or chronic liver diseases [mymemory.translated.net]

[…] of liver function did not appear to be of significance in the development of folate deficiency. [bloodjournal.org]

Such factors as the presence of ascites, an expanded plasma volume, a Patent portacaval shunting procedure, the type of alcoholic beverage imbibed, and the severity of impairment [bloodjournal.org]

Rib Tumor

The prognosis (outlook) depends on the degree of local tumor replacement and the extent of liver function impairment. [medicinenet.com]

Primary liver cancer (hepatocellular carcinoma) is the most common cancer in some parts of the world. [medicinenet.com]

Hepatorenal Syndrome

BACKGROUND: Type 2 hepatorenal syndrome (HRS2) is a functional renal impairment complicating end-stage liver disease. [ncbi.nlm.nih.gov]

[…] associated to rapid impairment in liver function and encephalopathy Type-1 HRS is associated to very poor prognosis Definition of Type-2 Hepatorenal Syndrome: Type-2 HRS [icascites.org]

impaired renal function. [rarediseases.org]

Liver Fibrosis

impair blood flow and cause disruption of liver functioning. [liverbasics.com]

Over time, these progressive conditions can lead to liver function impairment, liver cancer and the need for a liver transplant. [hepmag.com]

While the first antiretrovirals, which became available in particular D-drugs (especially didanosine and stavudine) and unboosted protease inhibitors, may impair liver function [ncbi.nlm.nih.gov]

Hepatic Brucellosis

Typically does not cause significant outward disease – but can lead to some amount of impaired liver function. No concern for consumption Hepatic Lipidosis [wgfd.wyo.gov]

Causes enlarged pale yellow liver. Generally resolves in elk after the rut, when they start to feed again. [wgfd.wyo.gov]

Encephalopathy

When normal liver functions are impaired by infection, alcohol, medication, or other factors, these toxic substances build up and can damage many organs, including the brain [radiology.ucla.edu]

In hepatic encephalopathy, toxins are not removed because liver function is impaired. [merckmanuals.com]

Normally, a healthy liver filters and breaks down toxic substances in the blood. [radiology.ucla.edu]

Intrahepatic Cholestasis

Viral and autoimmune hepatitis, and other possible causes of liver function impairment were excluded. Treatment with ursodeoxycholic acid improved biochemical markers. [ncbi.nlm.nih.gov]

PURPOSE: Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disorder characterized by maternal pruritus and impaired liver function. [ncbi.nlm.nih.gov]

As a result, bile builds up in the liver, impairing liver function. [ghr.nlm.nih.gov]

Cryptogenic Cirrhosis

Cryptogenic cirrhosis is a condition that impairs liver function. [ghr.nlm.nih.gov]

RESULTS: HCC patients with CC had similar impairments in liver function as patients with HCV infection (Child-Pugh class A: 53% vs 65%; P = .141). [ncbi.nlm.nih.gov]

Preeclampsia

Abnormal enzymes unable to degrade fatty acids will result in an accumulation of fatty acids in organs like the liver, impairing its function. [ncbi.nlm.nih.gov]

In severe cases, red blood cells can break down, blood platelet counts fall, liver and kidney function is impaired, and fluid can fill the lungs, causing shortness of breath [umassmed.edu]

[…] enzymes Low platelet count Oliguria (low urine output) less than 500ml per 24 hours Impaired kidney or liver functions MANAGEMENT AND TREATMENT There is no cure for preeclampsia [healthyslide.com]

Hepatic Encephalopathy

In hepatic encephalopathy, toxins are not removed because liver function is impaired. [merckmanuals.com]

Also, some toxins may completely bypass the liver through abnormal connections (called collateral vessels) that form between the portal venous system (which supplies blood [merckmanuals.com]