A liver abscess is composed of localized necrotic and inflammatory tissue within the liver. It is usually present following an infection with parasitic, fungal or bacterial microorganisms.
Infection of the bile ducts (cholangitis) is nowadays the most common underlying cause of liver abscess, especially among the elderly.…
Amebic liver abscess results as a complication of an amebic infection. It is diagnosed through evaluation of clinical and epidemiologic factors as well as serologic and possibly imaging studies.
Amebic liver abscess is a complication of amebiasis, which is transmitted via the feco-oral route through infected humans. The…
Echinococcosis is a disease caused by the parasites called tapeworms belonging to the Echinococcus genus. Humans get infected by ingesting the parasite eggs in contaminated water, food, or soil, and through having direct contact with the animal hosts.
Cystic echinococcosis The clinical presentation of cystic…
Polycythemia vera is a rare chronic myeloproliferative disorder.
An increase in red cell mass is the primary feature of polycythemia vera. Bone marrow analysis, however, shows a proliferation of all three myeloid lines: erythrocytes, granulocytes and platelets. The onset of polycythemia vera is often insidious. Early…
Tyrosinemia type 1 (TT1), also referred to as hepatorenal tryosinosis, is caused by an inborn error of metabolism. This genetic disorder affects the liver, kidney, and central nervous system. Without treatment, patients usually die in childhood.
This metabolic disease may present in infancy, early childhood, or beyond…
Fatty liver is the accumulation of triglycerides and other fats in the hepatocytes. It is commonly associated with alcohol, drugs, overnutrition or metabolic syndrome.
Fatty liver will induce slow and increasing malaise, weakness and anorexia. Hepatomegaly is seen in cases of fatty liver. Jaundice will be seen in around…
Hepatocellular adenomas are benign tumors of liver closely linked to oral contraceptive and anabolic steroid use that usually involve the right hepatic lobe. Cases have also been described in type I and III glycogen storage diseases and men with metabolic syndrome. Often clinically silent, this condition may be found…
Progressive familial intrahepatic cholestasis (PFIC) is a group of inherited cholestatic conditions that develop as a result of impaired bile secretion. It manifests in infancy or childhood and can progress to failure to thrive or even advanced liver disease. Severe cases often require liver transplantation.