Both immunodeficiency and secondary infection after scratching may provoke more severe local symptoms. … Local application of ice and possibly antihistamines may help to reduce inflammation and pruritus. … Most insect bites are presented in form of puncture wounds, papule formation, localized urticaria and pruritus.
Chronically, scaling may evolve to maceration of the local tissue exuding a foul smelling odor from the wound. … Hyperhidrosis (abnormally increased sweating) increases the risk of infection and makes treatment more difficult.
Complex regional pain syndrome is a condition characterized by onset of chronic pain that affects an arm or a leg. It is a rare form of disease and the type II variety often results from nerve injury.
The following are the various signs and symptoms experienced by individuals affected by complex regional pain…
Local symptoms may occur due to the mass of the tumor or its ulceration. … Although localized pain may occur in advanced cancer, the initial swelling is usually painless. … In localized cancer, surgery typically attempts to remove the entire mass along with, in certain cases, the lymph nodes in the area.
Diabetes mellitus is a common metabolic disorder of multiple etiology, characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism due to defects in insulin secretion, insulin action, or both. There are four main types of diabetes mellitus: type 1 diabetes mellitus, type 2…
Furthermore, PGE2 has vasodilatory effects, which is consistent with prolonged local vasodilation in digital clubbing. … Recently, it has been suggested that the locally acting mediator [[prostaglandin E2]] (PGE2) plays a role in the pathogenesis of PDP.
Pheochromocytoma is an adrenal tumor that excessively secretes catecholamines. The secretion of catecholamines from the chromaffin cells of the adrenals causes paroxysmal or persistent hypertension among patients. The catecholamines secreted from the adrenal tumor includes epinephrine, norepinephrine, and…
Homocystinuria is an autosomal recessive metabolic disease characterized by elevated levels of homocysteine. The most common genetic mutation involved in the disease targets cystathionine beta-synthase, an enzyme that catalyzes the conversion of methionine into cysteine.
Patients with homocystinuria can present…