Possible Causes for Localized Scleroderma in USA

  • Diffuse Scleroderma
    CREST Syndrome Localized Scleroderma Scleroderma Renal Disease Pulmonary Scleroderma
  • Nummular Dermatitis
    Localized Scleroderma

    Dermatitis (inflammation of the skin) presenting as disc- or coin-shaped lesions is called nummular or discoid dermatitis. This type of dermatitis is commonly seen among middle-aged or elderly patients and is associated with the presence of dry skin and cold weather. The cause of this condition is unknown, though id…[1]

  • Ataxia Telangiectasia
    Localized Scleroderma

    Ataxia telangiectasia (AT) is a rare neurodegenerative disorder inherited through an autosomal recessive pattern, mainly characterized by a progressive neurologic impairment together with cerebellar ataxia. The severity of AT varies between the subjects. Ataxia is undoubtedly one of the most important sings, and…[2]

  • Insect Bite
    Localized Edema

    Insect bites may be inflicted by mosquitos, fleas, bugs, lice and a plethora of other species pertaining to distinct families of the order insects. While they are of little medical interest in the vast majority of cases, immunocompromised or allergic patients may suffer from severe reactions to an insect bite. Most…[3]

  • CREST Syndrome
    Scleroderma Renal Disease

    Regular exercise makes your body more flexible to combat the limiting effects of local scleroderma.[4]

  • Systemic Scleroderma
    CREST Syndrome

    Systemic scleroderma is a connective tissue disorder, which affects the skin, vessels and organs such as the heart, digestive tract or lungs. Systemic scleroderma is a condition that affects a multitude of organs and can therefore lead to the onset of various symptoms. The extent of the symptomatology,…[5]

  • Primary Biliary Cirrhosis
    CREST Syndrome

    Primary biliary cirrhosis (PBC) is a chronic and progressive disease of the liver which involves destruction of the interlobular bile ducts. In many cases, primary biliary cirrhosis causes no symptoms. However, in certain percentage of individuals this disease is known to cause the following signs and symptoms: Dry…[6]

  • Scorpion Sting
    Localized Edema

    The sting of the scorpion causes discomfort (moderate to severe), which reduces over a period of time. Discomfort is often described as a painful or burning sensation at the site of the sting. Severe reactions of the sting such as difficulty in swallowing, blurred vision, seizures, uncontrolled eye-movements, thick…[7]

  • Hereditary Lymphedema
    Localized Edema

    Milroy's disease (MD) is a familial disease characterized by lymphedema, commonly in the legs, caused by congenital abnormalities in the lymphatic system. Disruption of the normal drainage of lymph leads to fluid accumulation and hypertrophy of soft tissues. It is also known as Milroy disease, Nonne-Milroy-Meige syndrome…[8]

  • Popliteal Cyst
    Localized Edema

    A popliteal cyst is a sac filled with synovial fluid that develops in the posterior knee. In adults, this is likely associated with knee trauma or underlying disease.  The clinical presentation is typically mild. For example, aches and tenderness may occur with physical activity and certain positions such as knee extension.…[9]

Further symptoms


  1. Nummular Dermatitis, Symptoma
  2. Ataxia Telangiectasia, Symptoma
  3. Insect Bite, Symptoma
  4. CREST Syndrome, Symptoma
  5. Systemic Scleroderma, Symptoma
  6. Primary Biliary Cirrhosis, Symptoma
  7. Scorpion Sting, Symptoma
  8. Wikipedia: Milroy's disease, CC-BY-SA-3.0
  9. Popliteal Cyst, Symptoma