Long Arm: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Long Arm

Marfan Syndrome

thin fingers and long arms and legs They may have a dislocation of the lens in the eye that also causes nearsightedness or myopia that can progress quickly They may have [web.archive.org]

He is extremely tall with a thin physique, a protruding chin and disproportionately long arms. Great attributes to be an Olympic swimmer. [raredr.com]

Children who have Marfan syndrome are usually tall and thin, with long arms, long double-jointed fingers, a short torso and very long legs. [childrenshospital.org]

Klinefelter Syndrome

These findings indicate that extra copies of the long arm of X have phenotypic expression, even though activated only in early development. [ncbi.nlm.nih.gov]

arm of the X chromosome, which shares some features of classical Klinefelter syndrome in many aspects, but patients are usually shorter than average height and have normal [ncbi.nlm.nih.gov]

[…] legs and arms indicating Klinefelter syndrome. [journal.ugm.ac.id]

Multiple Endocrine Neoplasia Type 2B

arm (band q11). [ncbi.nlm.nih.gov]

Multipoint analysis of RFLPs at FNRB, D10Z1, RBP3, and D10S15 gave a peak lod score of 7.12 at the midpoint between D10Z1 and RBP3 on the long arm (band q11). [ncbi.nlm.nih.gov]

[…] additional results in three generations of a 15th family have disclosed a peak total lod score of 8.89 at the midpoint between the centromere markers D10Z1 and RBP3 on the long [ncbi.nlm.nih.gov]

Klinefelter Syndrome with XY/XXY Mosaic

arms, and in some instances will develop breast tissue. [indiana.edu]

[…] attention, mild dyslexia or dyspraxia, low energy levels, and difficulty socialising or expressing feelings in teenagers – growing taller than expected for the family (with long [nhs.uk]

A tall, thin body with disproportionately long arms and legs. Obesity - this may cause a thicker waistline but it is often partially disguised by wider-than-normal hips. [patient.info]

Congenital Bile Acid Synthesis Defect Type 2

The AKR1D1 gene, located on the long arm of chromosome 7 (7q32-q33), encoding an enzyme called 4-3-oxo-5-? steroid dehydrogenase, found in liver cells. [ivami.com]

Each chromosome has a short arm designated “p” and a long arm designated “q”. Chromosomes are further sub-divided into many bands that are numbered. [rarediseases.org]

Bile acid CoA ligase deficiency is caused by mutations in the SLC27A5 gene located on the long arm of chromosome 19 (19q13.43). [rarediseases.org]

Persistent Polyclonal B-cell Lymphocytosis

FISH studies using a chromosome 3 long arm-specific probe provided evidence that all cases had both +i(3)(q10) and +3. [ncbi.nlm.nih.gov]

An additional chromosome long arm i(3)(q10) has recently been reported as a recurrent cytogenetic aberration, contrasting with a usual polyclonal immunoglobulin expression [ncbi.nlm.nih.gov]

Abnormality of the B-cell population is also evidenced by the presence of multiple bcl-2/Ig gene rearrangements and the finding of an additional long arm chromosome 3q+ (i3 [ncbi.nlm.nih.gov]

Partial Monosomy 18q

Syndrome associated with a deficiency of part of the long arm of chromosome no. 18. Arch Dis Child. 1967 Apr;42(222):140–146. [ncbi.nlm.nih.gov]

Partial deletion of the long arm of chromosome 18. [link.springer.com]

Engel : Partial E-18 long-arm deletion. Lancet 1968 I, 303. Google Scholar 10. Reinwein, H., L. Z. Corman u. U. [link.springer.com]

Jacobsen Syndrome

Abstract Jacobsen syndrome is a haploinsufficiency disorder caused, most frequently by terminal deletion of part of the long arm of chromosome 11, with breakpoints in 11q23.3 [ncbi.nlm.nih.gov]

Jump to navigation Jump to search Jacobsen syndrome is a multiple congenital anomaly/mental retardation (MCA/MR) contiguous gene syndrome caused by partial deletion of the long [wikidata.org]

To characterize these distal breakpoints and ultimately to further investigate the mechanisms of chromosome breakage, a 40-Mb YAC contig covering the distal long arm of chromosome [ncbi.nlm.nih.gov]

Monosomy 21q

Causes Chromosome 4, Monosomy 4q is caused by a partial deletion of the long arm of chromosome 4. [rarediseases.org]

[…] q long arm of chromosome r ring chromosome 46,X,r(X) Female with ring X chromosome rcp reciprocal translocation rob Robertsonian translocation t translocation 46,XX,t(2;8 [radford.edu]

This can be terminal (close to the end of the chromosome on the long arm or the short arm), or it can be interstitial (within the long arm or the short arm). [sapientfridge.org]

Chromosome 18p Deletion Syndrome

arm of chromosome 13 Deletion of long arm of chromosome 18 Deletion of part of autosome Deletion of short arm of chromosome 18 Deletion of X-chromosome and hypogammaglobulinemia [icd9data.com]

[…] normal centramere but no extra long arm the two deleted ends of the short arms so all in all out of the known disorders out there he dosn't fit into any one mold he dosn't [circleofmoms.com]

/Specific Code POA Exempt specified NEC Q93.89 Syndrome - see also Disease long arm 18 or 21 deletion Q93.89 ICD-10-CM Codes Adjacent To Q93.89 Q93.3 Deletion of short arm [icd10data.com]

Eunuchism

Educalingo cookies are used to personalize ads and get web traffic statistics. We also share information about the use of the site with our social media, advertising and analytics partners. PRONUNCIATION OF EUNUCHISM GRAMMATICAL CATEGORY OF EUNUCHISM Eunuchism is a noun. A noun is a type of word the meaning of[…] [educalingo.com]

Chromosome 19q13.11 Deletion Syndrome

1p36/19q13 Probe Set with ZyBlack Quenching Solution ZytoLight® Glioma 1p/19q Probe Set Deletions affecting the short arm of chromosome 1 (1p36) and the long arm of chromosome [generon.co.uk]

The 1p36.3 deletion together with the deletion of the long arm of chromosome 19 (19q13) are strongly correlated with gliomas with oligodendroglial morphology. [intellmed.eu]

For example, “chromosome 22q11” refers to band 11 on the long arm of chromosome 22. [rarediseases.org]

Congenital Malformation Syndromes Involving Early Overgrowth

Amniocentesis revealed a derivative chromosome 15, or der(15), with additional material at the end of the long arm of one chromosome 15. Parental karyotypes were normal. [tmu.pure.elsevier.com]

Chromosome analysis of the mother showed a reciprocal balanced translocation between long arms of chromosome 6 and 15, t (6;15)(q26;q22). [pubfacts.com]

Each chromosome has a short arm designated as "p" and a long arm identified by the letter "q". Chromosomes are further subdivided into bands that are numbered. [rarediseases.org]

Drayer Syndrome

An infant with deletion of the distal long arm of chromosome 15 (q26.1 → qter) and loss of insuline-like growth factor I receptor gene. [nature.com]

There is one subtelomeric signal on the long arm of one copy of chromosome 15, indicating a terminal deletion on the other copy of chromosome 15. [omicsonline.org]

arm of chromosome 15. [springermedizin.de]

Partial Trisomy 8q

[…] the short arm of chromosome 8, it is concluded that trisomy of the proximal part of the long arm of chromosome 8 causes most of the clinical findings of trisomy 8 mosaicism [ncbi.nlm.nih.gov]

We present a case of a fetus mosaic for trisomy of the entire long arm (q) of chromosome 8 without additional chromosomal aberrations. [ncbi.nlm.nih.gov]

[…] q long arm of chromosome r ring chromosome 46,X,r(X) Female with ring X chromosome rcp reciprocal translocation rob Robertsonian translocation t translocation 46,XX,t(2;8 [radford.edu]

Trisomy 18p

FISH mapping, with multiple region specific and locus specific probes from the short and long arm of chromosome 18, showed that the structure of the dicentric chromosome 18 [ncbi.nlm.nih.gov]

The fetus had a derivative chromosome 21 with an extra short arm of chromosome 18 attached to the terminal region of the long arm of chromosome 21. [ncbi.nlm.nih.gov]

Chromosomes have a short and a long arm. The short arm is labelled p ; the long arm is labelled q. [rumersrainbow.co.uk]

Ring Chromosome 15

The long arm of the defective chromosome is broken at band q24 or q25. [ncbi.nlm.nih.gov]

The ring chromosome lacked the short arms of the two translocated chromosomes 15 and was duplicated for a portion of the long arms near the centromere, probably cen leads [ncbi.nlm.nih.gov]

arm of chromosome 15. [ncbi.nlm.nih.gov]

Ring Chromosome 1

In 5 cases, the patients had a non-supernumerary ring chromosome 1 resulting in partial monosomies of the short and/or long arm of chromosome 1. [ncbi.nlm.nih.gov]

[…] q long arm of chromosome r ring chromosome 46,X,r(X) Female with ring X chromosome rcp reciprocal translocation rob Robertsonian translocation t translocation 46,XX,t(2;8 [radford.edu]

No loss of chromosomal material in the ring; FISH revealed that both the short-arm and long-arm specific subtelomeric regions for 11p and 11q were preserved in the RC and [edmcasereports.com]

Ring Chromosome 13

The more severely affected patient showed a break point at band 13q32 in the long arm of the ring, whereas in the less severely affected the loss of material during ring formation [ncbi.nlm.nih.gov]

These findings yielded different breaking points on the ends of both the short and long arms of chromosome 13 from those reported in the literature. [ncbi.nlm.nih.gov]

Based on similar changes in other tumors, it seems reasonable to also analyze a large number of adenomatous goiters for submicroscopic deletions of the long arm of chromosome [ncbi.nlm.nih.gov]

Ring Chromosome 18

Ring chromosome 18 syndrome is a chromosomal abnormality in which partial deletions occur at both ends of chromosome 18, that is, distally on the short and long arms. [ncbi.nlm.nih.gov]

Partial deletion of genetic material from the long arm of chromosome 18 results in a syndrome with multisystemic involvement, including dysmorphic features, intellectual disability [ncbi.nlm.nih.gov]

Phenotypic and clinical features of individuals with ring chromosome 18 [r(18)] vary with the extent of deletion of the short (18p-) or long arm (18q-). [ncbi.nlm.nih.gov]

Ring Chromosome 21

arm to long arm fusion that contains alpha-satellite DNA and two copies of the D21S65 locus, but lacks beta-satellite DNA and telomeric DNA. [ncbi.nlm.nih.gov]

These data were consistent with the breakage and reunion of short- and long-arm regions to form the r(21), resulting in deletion of varying amounts of 21q22.1 to 21qter. [ncbi.nlm.nih.gov]

Y chromosome microdeletion analysis ruled out the presence of any genomic deletions in the azoospermic factor a,b,c regions on the long arm of chromosome Y. [ncbi.nlm.nih.gov]

Ring Chromosome 11 Syndrome

White matter changes associated with deletions of the long arm of chromosome 18 (18q- syndrome): a dysmyelinating disorder? [journals.sagepub.com]

No loss of chromosomal material in the ring; FISH revealed that both the short-arm and long-arm specific subtelomeric regions for 11p and 11q were preserved in the RC and [edmcasereports.com]

Each chromosomes has a p and q arm; p (petit) is the short arm and q (next letter in the alphabet) is the long arm. [justjamesinfo.wordpress.com]

Ring Chromosome 10

[chr3:158573187_qterdelinschr8:(128534000_128546000)_qter] derivative chromosome 5, translocation between short arm chromosome 5 and long arm chromosome 10 with homology at [hgvs.org]

arm) of chromosome 22. [icd.codes]

No loss of chromosomal material in the ring; FISH revealed that both the short-arm and long-arm specific subtelomeric regions for 11p and 11q were preserved in the RC and [edmcasereports.com]

Ring Chromosome 22

The role of a putative tumor suppressor gene on the long arm of chromosome 22 in the pathogenesis of these tumors is also discussed. [ncbi.nlm.nih.gov]

A 1 Mb array CGH experiment on peripheral blood DNA showed a deletion of 5 terminal clones on the long arm of chromosome 22. [ncbi.nlm.nih.gov]

Ring Chromosome 14 Syndrome

[…] q long arm of chromosome r ring chromosome 46,X,r(X) Female with ring X chromosome rcp reciprocal translocation rob Robertsonian translocation t translocation 46,XX,t(2;8 [radford.edu]

Ring14 indicates an alteration of chromosome 14, which acquires a ring shape because the two ends, one of the long arm and the other of the short arm, join together. [ring14.org]

Interstitial deletions involve the loss of materials within the short arm or the long arm. [healio.com]

Ring Chromosome 19

His mother had an interstitial deletion of the long arm of chromosome 19 and the same ring chromosome. [biblio.ugent.be]

No loss of chromosomal material in the ring; FISH revealed that both the short-arm and long-arm specific subtelomeric regions for 11p and 11q were preserved in the RC and [edmcasereports.com]

A.: Partial deletion of the long arm of chromosome 18. Humangenetik 7, 359–360 (1969). Google Scholar Moore, M. [link.springer.com]

Ring Chromosome 7

FISH with subtelomeric probes showed the presence of normal short and long arm subtelomere signals on the normal and the del (7), but not the ring 7. [ashg.org]

This is the first patient carrying a mosaic neocentric SRC derived from the long arm of chromosome 7. [figshare.com]

[…] between the short arm of chromosome 7 at band 21.1 and the long arm of chromosome 9 at band 34.1 represents a chromosome schematically the major banding regions are indicated [quizlet.com]

AMACR Deficiency

Each chromosome has a short arm designated “p” and a long arm designated “q”. Chromosomes are further sub-divided into many bands that are numbered. [rarediseases.org]

Bile acid CoA ligase deficiency is caused by mutations in the SLC27A5 gene located on the long arm of chromosome 19 (19q13.43). [rarediseases.org]

Amino acid n-acyltransferase deficiency is caused by mutations in the BAAT gene located on the long arm of chromosome 9 (9q31.1). [rarediseases.org]

Ring Chromosome 9

arm) of chromosome 22. [icd.codes]

No loss of chromosomal material in the ring; FISH revealed that both the short-arm and long-arm specific subtelomeric regions for 11p and 11q were preserved in the RC and [edmcasereports.com]

In this case the patient has a partial monosomy for the distal short arm and distal long arm. [jmg.bmj.com]

Ring Chromosome 17

Figure 3 Cell 13.3, a 56.9-Mbp loss of the Y chromosome short-arm and long-arm material, and a 19.3-Mbp partial gain of the long arm of chromosome 22. [academic.oup.com]

No loss of chromosomal material in the ring; FISH revealed that both the short-arm and long-arm specific subtelomeric regions for 11p and 11q were preserved in the RC and [edmcasereports.com]

arm, associated with the deletion of the 21q telomeric region. [journals.lww.com]