People with Marfan tend to be tall, and thin, with long arms, legs, fingers and toes.
By age 5 years growth in height velocity increases and adults with Klinefelter syndrome are usually taller average with disproportionately long arms and legs.
Multiple endocrine neoplasia type 2B is a rare disorder in which aggressive medullary thyroid cancer, pheochromocytoma may lead to life-threatening blood pressure changes, and mucosal neuromas are included in the clinical presentation. The majority of patients develop symptoms by the first few years of age. Through…
Cockayne syndrome is a rare autosomal recessive multisystem condition characterized by dwarfism, birdlike facies, premature aging, photosensitivity, progressive neurological dysfunction and intellectual deficit. Patients who have the Cockayne Syndrome show the following: Poor feeding This is seen during infancy but in…
Cervical Spondylosis is a condition in which abnormal deterioration of the cervical cartilages and vertebrae causes chronic neck pain. It is usually the result of prior a damage to the neck, including work or life-style activities, although its occurrence is affected by genetic factors because some families show…
Pancoast syndrome is a term used to describe unilateral shoulder and arm pain, weakness, and atrophy of hand muscles and Horner's syndrome as a result of a mass in the lung apex compressing blood vessels and nerve trunks. Bronchogenic carcinoma is the most common underlying etiology. A detailed clinical and…
Subclavian steal syndrome (subclavian steal phenomenon, subclavian steal steno-occlusive disease) is a vascular syndrome caused by an occlusion in the subclavian artery proximal to the origin of the vertebral artery, resulting in retrograde flow of blood. The decreased blood flow to the posterior brain and upper…
Oligoarthritis refers to the simultaneous inflammation of several, but not more than four joints. It is a general term that describes a condition to be encountered in patients suffering from distinct autoimmune, infectious or idiopathic diseases, e.g., oligoarticular juvenile idiopathic arthritis, reactive arthritis, and…