Possible Causes for Long Bone Fracture in USA

  • Osteitis Deformans
    Long Bone Fracture

    Osteitis deformans, also known as Paget's disease, is a condition frequently observed in elderly patients, despite the fact that it's prevalence has decreased over the last 20 years. With unclear etiology, this pathological entity is characterized by abnormal behavior of osteoclasts and osteoblasts, leading to…[1]

  • Dyskeratosis Congenita
    Long Bone Fracture

    Dyskeratosis congenita is a general term for genetic disorders that lead to excess skin pigmentation, nail dystrophy and mucosal leukoplakia. Patients suffer and may die from distinct grades of bone marrow failure. To date, mutations affecting ten different genes have been identified as possible DC triggers.…[2]

  • Maffucci Syndrome
    Long Bone Fracture

    Maffucci syndrome is a rare congenital nonhereditary disease consisting of the development of multiple enchondromas, hemangiomas and, less commonly, lymphangiomas. Enchondromas have a potential for malignant transformation and cause bone deformation, shortening, and fractures, while hemangiomas may cause severe…[3]

  • Primary Hyperparathyroidism
    Long Bone Fracture

    Primary hyperparathyroidism is an endocrinological disorder characterized by an excess production of parathyroid hormone due to intrinsic alterations of the patient's parathyroid glands. Symptoms presented by patients suffering from PHPT result from excess mobilization of osseous calcium phosphate and…[4]

  • Langerhans-Cell Histiocytosis
    Long Bone Fracture

    Langerhans cell histiocytosis (LCH), also called Histiocytosis X, is a rare disease characterized by the proliferation and accumulation of Langerhans cells in various tissues. Langerhans cell histiocytosis may present with a variety of non-specific and specific inflammatory symptoms in various organs of the…[5]

  • Spinal Muscular Atrophy Type 1

    Spinal muscular atrophies are a group of neurodegenerative disorders in which genetic mutations lead to progressive damage of motor neurons in the spinal cord. Type 1 is most severe, with a very early onset of numerous symptoms that lead to death within the first few years of life in the vast majority of cases.…[6]

  • Spinal Muscular Atrophy

    Spinal muscular atrophy is a genetic disorder characterized by progressive muscular weakness. The different types of spinal muscular atrophy may present differently but clinical symptomatology may be similar to some extent. The following system-wise presentation is commonly in seen in SMAs: General Appearance:…[7]

  • Adamantinoma

    Adamantinomas are rare, slow growing malignant bone tumors, which occurs almost exclusively in the long bones. One of the most common traits of this tumor is its predilection for the long bones. It occurs here in 97% of cases. On the long bones, it focuses on the tibia in 80% -85% of cases. It is therefore its most…[8]

  • Cervical Cancer

    Cervical cancer is the cancer that originates in the cervix of women. It is the 3rd most common cause of cancer related deaths worldwide. The early stage of cervical cancer is symptomless. During the later stages, as the disease progresses, women would experience vaginal bleeding, pain during intercourse and…[9]

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Further symptoms

Similar symptoms


  1. Osteitis Deformans, Symptoma
  2. Dyskeratosis Congenita, Symptoma
  3. Maffucci Syndrome, Symptoma
  4. Primary Hyperparathyroidism, Symptoma
  5. Langerhans-Cell Histiocytosis, Symptoma
  6. Spinal Muscular Atrophy Type 1, Symptoma
  7. Spinal Muscular Atrophy, Symptoma
  8. Adamantinoma, Symptoma
  9. Cervical Cancer, Symptoma