Skeletal malformations often involve the spine, especially lordosis (front-to-back spine curvature) and scoliosis (sideway spine curvature). … Other signs may be: Abnormal spine curvature (scoliosis and lordosis) Short stature Raucous voice Considerable reduction of pain and temperature sensitivity Vision problems … Key features can involve other body parts, like spine (scoliosis and lordosis), kidney, the immune system, and frequent episodes of peripheral neuropathy like decreased sensitivity
The spine is severely distorted as well along with significant shortening due to marked lordosis. … nervous system (CNS) and anatomic structures of the fetus can be clearly visualized and the characteristic malformations of iniencephaly, such as a shortened trunk, marked lordosis
All other etiological factors such as spinal lordosis and body casts also cause the characteristic anatomic defect of SMA. … SMA syndrome can be prevented by avoiding body casts which aggravate lumbar lordosis or distort the abdominal shape and structure. … Other risk factors of SMA syndrome include laxity of the abdominal wall, lordosis, and use of body casts, hence SMA syndrome is also called cast syndrome.