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11 Possible Causes for Loss of Anterior Horn Cells and Gliosis in the Spinal Cord

  • Progressive Muscular Atrophy

    The neuropathological examination revealed not only neuronal loss with gliosis in the facial nucleus, hypoglossal nucleus, and anterior horns of the spinal cord, but also[ncbi.nlm.nih.gov] Neuropathological examination disclosed not only neuronal loss with gliosis in the hypoglossal nucleus and anterior horns of the spinal cord, but also loss of Betz cells and[ncbi.nlm.nih.gov] loss of Betz cells and degeneration of the pyramidal tracts.[ncbi.nlm.nih.gov]

  • Lenegre Disease

    Autopsy in 2 affected members showed that the neuropathy was axonal; mild to moderate loss of anterior horn cells in the spinal cord and pigmentary loss with gliosis in the[findzebra.com] […] of anterior horn cells in the spinal cord and substantia nigral pigmentary loss with gliosis; Normal or slightly reduced nerve conduction velocity; Axonal loss with little[findzebra.com] […] changes GI: Chronic diarrhea; Nausea; Vomiting Cardiac: Heart block Oncology: Enhanced neurotoxicity of vincristine Misc: More severe in homozygotes Lab: Mild to moderate loss[findzebra.com]

  • Hyperpyrexia

    Neuropathological study of that patient showed severe loss of Purkinje cell with gliosis, neuronal loss in dentate nucleus, substantia nigra, and anterior horn cells of spinal[annalsofian.org] Niizato et al. (2006) have reported a single case of anterior horn cell degeneration in a schizophrenic patient who died from heat stroke.[annalsofian.org] cord and degeneration of bilateral pyramidal tract. [6] We suggest hyperpyrexia-induced cerebellar and anterior horn cell degeneration in the spinal cord as the pathogenesis[annalsofian.org]

  • Spinal Cord Lesion

    Examination of the spinal cord revealed loss and degeneration of nerve cells with marked gliosis in the medial motor nuclei of the anterior horns.[ncbi.nlm.nih.gov] A symmetric degeneration in the bilateral anterior columns which has never been described as a spinal cord lesion in the stiff-man syndrome was also seen.[ncbi.nlm.nih.gov]

  • Subarachnoid Abscess

    cord with nerve roots, atrophy with amyotrophic lateral sclerosis, gross Spinal cord, loss of anterior horn cells with amyotrophic lateral sclerosis, microscopic Spinal cord[library.med.utah.edu] , lateral column degeneration with gliosis, amyotrophic lateral sclerosis, microscopic, Luxol fast blue stain Cerebrum, Tay-Sach's disease, high power microscopic Neuronophagia[library.med.utah.edu] […] disease, gross Cerebrum, coronal section, multiple sclerosis, gross Cerebrum, coronal section, multiple sclerosis, gross [MRI] Cerebrum, multiple sclerosis, microscopic Spinal[library.med.utah.edu]

  • Chronic Progressive External Ophthalmoplegia

    , Clarke columns, and anterior horn cells of the spinal cord.[demneuropsy.com.br] […] associated with reactive gliosis in the following structures: substantia nigra, dentate nucleus of the cerebellum, red nucleus, pontine nuclei, other cranial nerve nuclei[demneuropsy.com.br] […] level of chromosome 14 (32,12), having a range of between 56 to 86 trinucleotíde repeats (normal alleles 12-47).2,3,10,16-21 Neuropathological examination shows neuronal loss[demneuropsy.com.br]

  • Ataxia Telangiectasia

    Other pathological changes include cerebellar cortical atrophy, diffuse fibrillary gliosis, and degeneration of the anterior horn cells of the spinal cord.[emedicine.com] This syndrome is characterized by a severe loss of Purkinje cells and, to a lesser degree, the basket and granular cells of the cerebellar cortex.[emedicine.com]

  • Cerebral Lipidosis

    In the spinal cord, there was some loss of the anterior horn cells and the remaining neurons showed a moderate enlargement.[docslide.net] The nerve cells of the dentate nuclei showed marked swelling, and in Holzer preparations a slight gliosis in the arca surrounded by the dentate nuclei was observed.[docslide.net]

  • Neuronal Ceroid Lipofuscinosis 5

    The pathology has also been observed in the basal ganglia, thalamus, brainstem and spinal cord anterior horn cells (6).[path.upmc.edu] The pathological process is associated with progressive and selective neuronal loss and gliosis with secondary white matter degeneration.[path.upmc.edu]

  • Tauopathy

    In the spinal cord, loss of the anterior horn cells and degeneration of the corticospinal tracts were a characteristic feature.[ncbi.nlm.nih.gov] The substantia nigra showed moderate neuronal loss and gliosis.[ncbi.nlm.nih.gov]

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