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26 Possible Causes for Loss of Appetite, Mutation in the WWOX Gene

  • Epithelial Ovarian Cancer

    TP53 and PTEN are among the best known tumor suppressor genes involved in EOC pathogenesis, but mutations have also been found in genes OPCML and WWOX, among others.[symptoma.com] […] of appetite, Feeling full after eating little, Gas and/or diarrhea, Nausea and vomiting, and Abnormalities in menstruation.[emedicinehealth.com] Side effects can include: nausea, vomiting diarrhea hair loss loss of appetite mouth sores anemia infections, because the white blood cell count is low The damaged healthy[medicalnewstoday.com]

  • Esophageal Carcinoma

    Copy-number analysis revealed higher rates of deletions of putative fragile site genes FHIT or WWOX, suggestive of differences in the underlying genomic instability between[nature.com] Symptoms and signs of oesophageal cancer which may cause a patient to present to a doctor include: Dysphagia Weight loss Loss of appetite Odynophagia Hoarseness Melaena Retrosternal[patient.info] Weight loss: Weight loss in the patients of esophageal carcinoma is due to dysphagia and anorexia.[symptoma.com]

  • Severe Neonatal-Onset Encephalopathy with Microcephaly

    Homozygous and compound heterozygous mutations in the WWOX gene (16q23) have been found in several families.[disorders.eyes.arizona.edu] At risk for a loss of appetite. [58] [60] One infant patient noted with failure to thrive and diarrhea. [63] Risk for renal and liver impairment and systemic infection with[autoinflammatory-search.org] Syphilis Toxoplasmosis Varicella Zika virus Intrauterine event or problem Death of twin Placental insufficiency – extreme Vascular incident such as stroke Maternal disease Anorexia[pediatriceducation.org]

  • Primary Effusion Lymphoma

    In PEL the p53 and PTEN genes are rarely mutated. P53 mutations accumulate after chemotherapy ( Petre et al., 2007 ; Chen et al., 2010 ).[journal.frontiersin.org] In the second case, an HIV-uninfected 94-year-old man was affected by anorexia, fatigue, shortness of breath and nonproductive cough.[ncbi.nlm.nih.gov] ; changes in appetite Fatigue and weakness, headache High temperatures and excessive night sweats (may be recurrent) Anemia (low red blood cell count) Frequent infections[dovemed.com]

  • Autosomal Recessive Deafness 103

    The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation. Brain. 2014;137:411–9.[cerebellumandataxias.biomedcentral.com] Few studies have used Voxel-Based Morphometry (VBM) to examine brain structure in Anorexia Nervosa patients.[68.penitentiary.us] The purpose of the present study was to investigate a sample of Anorexia Nervosa restrictive type (AN-r) adolescent patients in the early stages of the illness, using VBM[68.penitentiary.us]

  • Autosomal Recessive Deafness 76

    The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation. Brain. 2014;137:411–9.[cerebellumandataxias.biomedcentral.com] Few studies have used Voxel-Based Morphometry (VBM) to examine brain structure in Anorexia Nervosa patients.[1tq.moult.us] The purpose of the present study was to investigate a sample of Anorexia Nervosa restrictive type (AN-r) adolescent patients in the early stages of the illness, using VBM[1tq.moult.us]

  • Ataxia

    The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation.[ncbi.nlm.nih.gov] […] throat 3 Mouth irritation 1 Nausea 2 Vomiting 1 Loss of appetite 1 Cardiopulmonary Shortness of breath 2 Palpitations 2 Integumentary Excess sweating 1 Itching 1 Burning[cdc.gov] […] noun mass noun Medicine The loss of full control of bodily movements. ‘She then began to complain of decreased appetite, weight loss, urinary incontinence, and ataxia.’[en.oxforddictionaries.com]

  • Female Infertility due to Gonadal Dysgenesis

    A few rare cases have been associated with mutations in the steroidogenic factor 1 ( SF1 or NR5A1 ) gene, the protein Wnt-4 ( WNT4 ) gene, and the CBX2, GATA4 and WWOX genes[rarediseases.org] Diseases such as nervous anorexia, diabetes, pernicious anemia, lupus, etc. Familiar history. Herpes zoster or cytomegalovirus infections.[invitra.com] Menstrual dysfunction in anorexia nervosa. J Pediatr Adolesc Gynecol. 2004;17:81–5. 36. Drinkwater BL, Nilson K, Ott S, Chesnut CH III.[aafp.org]

  • Spinocerebellar Ataxia Type 12

    Mutation in the WWOX gene, D. schematic of the WWOX gene). Figure adapted from WWOX.[epilepsygenetics.net] . • No h/o fever, headace,seizures • No h/o loss of appetite / weight loss • No h/o skin rashes • No h/o trauma • No h/o any drug intake/exposure to toxins • No h/o recent[slideshare.net] Performing exome sequencing in the younger sister, the authors identified 16 genes with functionally relevant homozygous mutation and focused on the WWOX gene, coding for[epilepsygenetics.net]

  • Carcinoma

    Copy-number analysis revealed higher rates of deletions of putative fragile site genes FHIT or WWOX , suggestive of differences in the underlying genomic instability between[nature.com] […] of appetite/weight loss Persistent cough or hoarseness Thickening or lump in any part of the body Changes in bowel or bladder habits Unexplained weight gain or loss Jaundice[upmc.com] […] of appetite Unexplained weight loss of greater than 5 percent over a six- to 12-month period But there also difference that characterized this form of cancer versus others[lungcancer.about.com]

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