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17 Possible Causes for Loss of Axillary Hair, Midline Defects, Syncope

  • Panhypopituitarism

    CONCLUSION: These data demonstrate that homozygous HESX1 mutation causing an R160H substitution can result in panhypopituitarism without midline defects.[] Nonspecific symptoms are most frequently seen in the form of exercise intolerance, abdominal pain, loss of axillary and pubic hair weakness or fatigue, Increase in weight,[] We report on a neonate with unexplained heart failure and minor physical anomalies, suggesting a midline defect. She was diagnosed with complete CPHD.[]

  • Anterior Pituitary Hypofunction

    It is characterized by congenital hypogonadotropic hypogonadism and anosmia, possibly with additional midline defects.[] […] of pubic and axillary hair Atrophy of breast and Testis What are the steps in evaluating anterior pituitary hypofunction?[] […] presenting signs and symptoms included headache (63%), vomiting (50%), visual field defects (61%), ocular paresis (40%), mental deterioration (13%), hyponatremia (13%), and syncope[]

  • Suprasellar Tumor

    However, the field defect in tilted-disc syndrome is unchanging and does not respect the vertical midline, whereas the field defects in chiasm-compressive lesions are progressive[] Physical examination revealed axillary and groin hair loss, hypogonadism, orthostatic hypotension, and a possible mild bitemporal visual field deficit.[] He denied any disturbances in visual perception, history of seizure or syncope. Neurologic and general examination yielded no further findings.[]

  • Adrenal Insufficiency Secondary to Hypopituitarism

    Neonates Hypoglycemia Micropenis Conjugated hyperbilirubinemia Adrenal crisis secondary to hypocortisolism (vomiting, hypotension) Failure to thrive Midline defects (cleft[] Loss of pubic or axillary hair in women, delayed puberty in children.[] Note any loss of axillary and pubic hair that could be caused by decreased androgen levels.[]

  • Hypopituitarism

    , eye anomalies, and midline/ventral defects).[] […] of axillary and pubic hair In women: cessation of menstruation (amenorrhea), breast atrophy, vaginal dryness, absence of milk production in new mothers (Sheehan’s syndrome[] Four months later, he presented with a sudden onset of diplopia, syncope, headache, general malaise and loss of appetite.[]

  • Hypothyroidism

    defects of the brain, should alert the physician to suspect the diagnosis of septo-optic dysplasia.[] Physical signs of hypothyroidism include the following: Weight gain Slowed speech and movements Dry skin Jaundice Pallor Coarse, brittle, straw-like hair Loss of scalp hair[] Patient I presented with persistent respiratory distress, facial swelling and recurrent syncopal attacks.[]

  • Hypogonadotropic Hypogonadism Type 8

    […] producing GRH–gonadotropin-releasing hormone; FSH and LH impairs sperm and androgen production Clinical Delayed puberty, micropenis, eunuchoid features, cryptorchidism, midline[] Thus, palor or loss of pubic and axillary hair is more common in patients with associated adrenal insufficiency that completes the androgen deficiency [ 8 ].[] Fatigue, dyspnea, cyanosis, palpitations, syncope Patients with Kallmann syndrome may have any of these symptoms as manifestations of congenital heart disease such as atrial[]

  • Congenital Isolated ACTH Deficiency

    Neonates who have congenital defects of the pituitary or hypothalamus may have hypoglycemia (which also can occur in older children), midline defects (eg, cleft palate), or[] […] and decreased axillary and pubic hair.[] Syncope or dizziness (due to hypotension). Confusion. Personality change. Irritability. Loss of pubic or axillary hair in women, delayed puberty in children.[]

  • Central Precocious Puberty

    […] brain defects (1).[] […] or penile enlargement, axillary hair and odor, acne, muscular hypertrophy, aggressiveness – denoting androgen excess; and Cushing syndrome – weight gain, central obesity,[] Syncope diagnostic scores. Prog Cardiovasc Dis. 2013; 55 (4):390-5. doi: 10.1016/j.pcad.2012.10.011. [PubMed: 23472776 ]. 37.[]

  • Absence or Deformity of Leg- Cataract Syndrome

    Affects critical genes in domain 1 (IGF-2 (overexpression of foetal growth factors) and H19 (tumour suppressor gene)) 5 common feats: Macroglossia Macrosomia Midline abdominal[] The syndrome may also include: Poor breast or nipple development on the affected side – more obvious in females Supernumerary nipples Loss of subcutaneous fat Loss of axillary[] […] young Neurofibromatosis-Noonan syndrome Methylmalonic acidemia and homocysteinemia type cblX X-linked lissencephaly with abnormal genitalia Ventricular extrasystoles with syncopal[]

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