Create issue ticket

50 Possible Causes for Loss of Motor Functions, Progressive Action Tremor

  • Progressive Myoclonic Epilepsy Type 3

    , action myoclonus, infrequent generalized seizures, and ataxia) or with proteinuria that progresses to renal failure.[ 42 ] Despite severe neurologic disability due mainly[thieme-connect.com] (EPM4) has been identified to be caused by pathogenic variants in SCARB2 .[ 41 ] It typically presents at ages 15 to 25 years either with neurologic symptoms (including tremor[thieme-connect.com]

  • Parkinson's Disease

    […] reduction in speed and amplitude of repetitive actions) and at least one of the following: (i) muscular rigidity, (ii) 4–6 Hz rest tremor and (iii) postural instability not[dx.doi.org] In early adulthood, the MitoPark mice show a slowly progressing loss of motor function that accompanies these cellular changes.[ncbi.nlm.nih.gov] Parkinson disease is the primary form of parkinsonism, a group of chronic disorders in which there is progressive loss of motor function due to the degeneration of neurons[britannica.com]

  • Spinocerebellar Ataxia Type 12

    SCA12 is a late-onset, autosomal dominant, slowly progressive disorder. Action tremor is the usual presenting sign.[jhu.pure.elsevier.com] […] of normal motor function, resulting in impaired muscle movement) CAG repeat, 5q SCA13 ( KCNC3 ) Childhood or adulthood depending on mutation Depending on KCNC3 (a kind of[en.wikipedia.org] SCA12 is a late-onset, autosomal dominant , slowly progressive disorder. Action tremor is the usual presenting sign.[ncbi.nlm.nih.gov]

  • Essential Tremor

    Characterised by a progressive tremor of the upper extremities, present in posture and action, without other neurological signs or symptoms.[bestpractice.bmj.com] Potential adverse effects include intracerebral hemorrhage, motor weakness, dystonia, speech disturbance, and memory loss.[emedicine.medscape.com] Essential tremor is a slowly progressive disease that causes shaking while assuming static positions (postural tremor) and during movements (action tremor).[blogs.biomedcentral.com]

  • Jankovic Rivera Syndrome

    […] myoclonic and atonic seizures, tremulousness/tremor, and sensorineural hearing loss.[ncbi.nlm.nih.gov] Abstract Spinal muscular atrophy (SMA) is a clinically and genetically heterogeneous disease characterised by loss of motor function and muscle atrophy due to anterior horn[doi.org] Myoclonic epilepsy typically begins in late childhood after the onset of weakness and can include jerking of the upper limbs, action myoclonus, myoclonic status, and eyelid[ncbi.nlm.nih.gov]

  • Shy Drager Syndrome

    In addition, patients with MSA-C may have tremor with action, which is different from the resting tremor seen in typical Parkinson's disease.[bcm.edu] "Symptoms tend to appear in a person's 50s and advance rapidly over the course of 5 to 10 years, with progressive loss of motor function and eventual confinement to bed,"[universityherald.com] Symptoms tend to appear in a person’s 50s and advance rapidly over the course of 5 to 10 years, with progressive loss of motor function and eventual confinement to bed.[ninds.nih.gov]

  • X-linked Distal Spinal Muscular Atrophy Type 3

    Spinocerebellar ataxia type 12 (SCA12) is an autosomal dominant disorder characterized by action tremor of the upper extremities progressing to ataxia and other cerebellar[chginc.org] […] milestones in less affected individuals with Types II or III SMA Chronic phase: motor unit loss may appear to plateau 12 Functional motor abilities may remain stable for[togetherinsma-hcp.com] Loss of this gene results in loss of function of specific proteins required for RNA processing.[patient.info]

  • Cerebral Palsy

    The most common manifestation of ataxic cerebral palsy is intention (action) tremor, which is especially apparent when carrying out precise movements, such as tying shoe laces[en.wikipedia.org] Cerebral palsy (CP) is a broad term that describes a group of nonprogressive neurological (brain) disorders that cause the loss of normal motor function.[columbianeurology.org] […] of motor function; assessed by developmental paediatrician at 2 years 1 RCT: defined severe cerebral palsy as not walking or unlikely to walk unaided by 2 years; children[doi.org]

  • Olivopontocerebellar Atrophy

    Tremor - Postural, resting, or both Bradykinesia plus at least 1 parkinsonian feature Cerebellar Dysfunction • Gait ataxia (wide-based stance with steps of irregular length[physio-pedia.com] Progressive loss of motor skills, eventually lead to a person becoming bed dependent and death generally occur within 10 years or less after diagnosis.[secure.ssa.gov] […] reduction in speed and amplitude during repetitive actions • Rigidity • Postural instability not caused by primary visual, vestibular, cerebellar, or proprioceptive dysfunction[physio-pedia.com]

  • Bradykinesia

    The usual course is for gradual progression. 26-9. How do you recognize essential tremor? Answer 26-9.[dartmouth.edu] PD was simulated as a reduction in dopamine levels, and a loss of functional segregation between two competing motor modules.[ncbi.nlm.nih.gov] Reduced levels of dopamine affect the body’s motor function, causing movement disorders such as bradykinesia — a classic symptom of Parkinson’s disease.[parkinsonsnewstoday.com]

Further symptoms