Motor nerve conduction velocities are decreased, and sural nerve biopsies show loss of myelinated fibers.
[ncbi.nlm.nih.gov]
This results in loss of myelin and impaired nerve signal transmission.
[charcot-marie-toothnews.com]
Histopathological findings associated with Q163X mutation include severe loss of myelinated axons, moderate loss of unmyelinated fibers, and onion bulb formations, with no
[scielo.org.co]