Possible Causes for Low Birth Weight Distal Spinal Muscular Atrophy Type 1 SMARD1 patients usually present low birth weight, diaphragmatic palsy and distal muscular atrophy. [ncbi.nlm.nih.gov] Patients typically have a history of intrauterine growth retardation, low birth weight, feeble cry, weak suck and failure to thrive and present with inspiratory stridor, recurrent [orpha.net] Seckel Syndrome There remains a heterogeneous group of low birth weight microcephalic dwarfism yet to be defined. [ncbi.nlm.nih.gov] Cephaloskeletal Dysplasia (Osteodysplastic Primordial Dwarfism Type I): An extremely rare inherited disorder characterized by low birth weight, dwarfism, microcephaly, and [accessanesthesiology.mhmedical.com] Seck·el syn·drome ( sek'ĕl ), [MIM*210600] an autosomal recessive disorder characterized by low birth weight, dwarfism, microcephaly, large eyes, beaked nose, receding mandible [medical-dictionary.thefreedictionary.com] Wolf-Hirschhorn Syndrome An autosomal dominant [MIM 194190] chromosome deletion complex characterised by low birth weight, microcephaly, ‘Greek helmet’ facies—micrognathia, hypertelorism, epicanthus [medical-dictionary.thefreedictionary.com] Children with Wolf-Hirschhorn usually have: a low birth weight slow weight gain difficulty with feeding delayed development (see entry Global Developmental Delay ) microcephaly [contact.org.uk] Chromosome 18p Deletion Syndrome Affected neonates are hypotonic and have low birth weight, microcephaly, a round face with wide-set eyes, downward slanting of the palpebral fissures (with or without epicanthal [merckmanuals.com] The baby was admitted to the Neonatal Intensive Care Unit for eight days due to low birth weight. [ijcasereportsandimages.com] weight less than 10th percentile Low birth weight [ more ] 0001518 Sporadic No previous family history 0003745 Showing of 53 | Last updated: 5/1/2019 If you need medical [rarediseases.info.nih.gov] Cockayne Syndrome At birth, they both appeared normal, although both demonstrated a low birth weight and breech presentation. [ncbi.nlm.nih.gov] CS should be considered in babies with low birth weight and congenital cataract. [ncbi.nlm.nih.gov] Cockayne syndrome (CS) is a recessively inherited neurodegenerative disorder characterized by low-to-normal birth weight; growth failure; brain dysmyelination with calcium [ncbi.nlm.nih.gov] Autosomal Recessive Primary Microcephaly Type 10 Typically, people with primordial dwarfism are born with very low birth weights. [en.wikipedia.org] Hallermann-Streiff Syndrome B., a 5-day-old white female, was admitted to the Indiana University Medical Center because of low birth weight (4 lb.) and peculiar facies. [pubs.rsna.org] weight less than 10th percentile Low birth weight [ more ] 0001518 Sparse hair 0008070 Spina bifida 0002414 Sporadic No previous family history 0003745 Telangiectasia 0001009 [rarediseases.info.nih.gov] GROWTH AND DEVELOPMENT Birth weight is normal in about 64%, prematurity and/or low birth weight occurring in the other 36% [Su- zuki et al., 19701. [vdocuments.site] 3M Syndrome Type 3 Clinical description Infants present with severe postnatal (and prenatal) growth retardation, usually associated with a low birth weight (<2nd centile). [orpha.net] In most cases, infants with Three M syndrome are unusually small and have a low birth weight despite being carried to term. [rarediseases.org] Diagnostic methods Diagnosis is based primarily on clinical features (e.g. low birth weight, severe growth retardation, prominent fleshy heels). [orpha.net] Seckel Syndrome Type 2 UniProtKB/Swiss-Prot : 72 Seckel syndrome 2: A rare autosomal recessive disorder characterized by proportionate dwarfism of prenatal onset associated with low birth weight [malacards.org] It is characterised by proportional short stature, low birth weight, dysmorphic facial appearance, and mental retardation. [cambridge.org] Definition A rare autosomal recessive disorder characterized by proportionate dwarfism of prenatal onset associated with low birth weight, growth retardation, severe microcephaly [uniprot.org] Johanson-Blizzard Syndrome The severity of this condition varies from one case to another presenting the abnormal facial features, dental problems and low birth weight. [mybiosource.com] Clinical presentation There is wide variability in the clinical presentation, but common features are: low birth weight hypotonia intellectual disability (wide range) delayed [radiopaedia.org] weight less than 10th percentile Low birth weight [ more ] 0001518 Sparse scalp hair Scalp hair, thinning Sparse, thin scalp hair sparse-absent scalp hair [ more ] 0002209 [rarediseases.info.nih.gov] 15q24 Deletion Syndrome Low birth weight (less than third centile) Low birth weight (less than fifth centile) Low birth weight (less than second centile) 75th centile OFC Less than third centile [academic.oup.com] Symptoms of 15q24 microdeletion syndrome include: Mild to moderate intellectual disability Low birth weight (1/3 of patients) Failure to thrive Difficulty feeding Growth difficulties [patientworthy.com] low birth weight obesity (less common) Skeletal Feet: abnormal insertion of the toes Endocrine Features: growth hormone deficiency (2 patients) hypogonadotropic hypogonadism [malacards.org] 17q23.1q23.2 Microdeletion Syndrome Additional abnormalities, such as microcephaly, low birth weight, postnatal growth retardation, and hearing loss presented in several cases [1,2], and multiple cases with [cureus.com] Antenatal Bartter Syndrome Neonatal bartter syndrome in an extremely low birth weight baby. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2019 Jul 18];28:1162-4. [sjkdt.org] Neonatal bartter syndrome in an extremely low birth weight baby. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2022 Nov 3];28:1162-4. [sjkdt.org] Abstract Early diagnosis of Bartter syndrome (BS) in the neonatal period is a clinical challenge, more so in an extremely low birth weight (ELBW) baby because of the inherent [sjkdt.org] Kenney-Caffey Syndrome Clinical Correlations: Infants are born with a low birth weight and the head seems abnormally large perhaps because of this. [disorders.eyes.arizona.edu] as low birth weight is one of the first symptoms. [en.wikipedia.org] (congenital) and low birth weight may be one of the first symptoms. [rarediseases.org] Chromosome 16q22 Deletion Syndrome The former includes low birth weight, hypotonia, feeding disturbances, failure to thrive, and delayed psychomotor development. [docksci.com] Clinical description At birth, approximately 1/3 of patients have low birth weight consistent with intrauterine growth retardation. [orpha.net] He shows the typical symptoms of 16q22 deletion syndrome, such as low birth weight, global developmental delay, short stature, microcephaly, low set dysmorphic ears, mild [molecularcytogenetics.biomedcentral.com] Drayer Syndrome low birth weight Growth Other: failure to thrive intrauterine growth retardation Growth Height: short stature Head And Neck Eyes: strabismus blepharophimosis Skeletal Feet [malacards.org] Birth weight 1940g (60th centile), length 44cm (50th centile), head circumference 31.2cm (above 60th centile); dysmorphic features: short palpebral fissures, broad and flat [ssmc-tl.com] […] cryptorchidism hypospadias micropenis Skeletal Hands: brachydactyly absence or hypoplastic middle phalanges Cardiovascular Heart: septal defects congenital cardiac anomalies Growth Weight [malacards.org] Dwarfism Type Levi […] t=27118 snub-nose dwarfism Dwarfism characterised by low birth weight, snub nose, and stocky build; autosomal dominant inheritance. [encyclo.co.uk] low birth weight Head And Neck Nose: snub-nose Growth Height: proportionate dwarfism Clinical features from OMIM: 127100 Drugs & Therapeutics for Dwarfism, Levi Type Genetic [malacards.org] People with primordial dwarfism are born at extremely low birth weights. [dailymail.co.uk] 3q29 Microdeletion In particular, mild to moderate cognitive deficits, speech delay, low birth weight, a high nasal root, and ocular abnormalities are common findings (Table 1). [bmcmedgenomics.biomedcentral.com] Nonetheless, 64% of patients had a low birth weight and feeding problems, while ~30% of cases had neuropsychiatric disorders (anxiety, panic attacks, depression or bipolar [frontiersin.org] Infants often have a high-pitched cry and low birth weight. [portal.bsc.gwu.edu] Shwachman Syndrome weight less than 10th percentile Low birth weight [ more ] 0001518 Specific learning disability 0001328 Steatorrhea Fat in feces 0002570 Showing of 53 | Last updated: 3/1 [rarediseases.info.nih.gov] The low percentile at birth for length and weight indicates that prenatal retardation occurs, then continuing in the postnatal period. [bmjopen.bmj.com] […] epiphysiolysis Slipped end part of innermost thighbone 0006461 Respiratory distress Breathing difficulties Difficulty breathing [ more ] 0002098 Small for gestational age Birth [rarediseases.info.nih.gov] Pearson Syndrome Systemic Features: Low birth weight, failure to thrive, hypoplastic anemia and exocrine pancreatic dysfunction are often seen in infancy. [disorders.eyes.arizona.edu] Neonates may be well at birth, but some 40% of patients present in the first year with persistent hypoplastic anemia, other cytopenias, low birth weight, microcephaly, and [emedicine.medscape.com] Signs and symptoms of Pearson syndrome Birth weight may have been low, and the infant may not have gained weight well. This may be confirmed with a careful growth chart. [emedicine.medscape.com] Syndromic Diarrhea His paper described 2 siblings who presented with low birth weight, dysmorphic features and abnormal ‘wooly’ hair6. [gradesfixer.com] birth weight, [4],[5],[6] variable immunodeficiency-like defective antibody responses, defective antigen-specific skin tests and monoclonal hyperimmunoglobulinemia A, [3] [saudijgastro.com] The relationship between low birth weight, dysmorphism, severe diarrhea, hair shaft defect, immune deficiency and neonatal hemochromatosis-like liver disease is unclear. [doi.org] Fetal Akinesia - Cerebral and Retinal Hemorrhage Syndrome birth weight Prenatal Manifestations Movement: decreased fetal movements Clinical features from OMIM: 615368 Human phenotypes related to Lethal Congenital Contracture Syndrome [malacards.org] fetal 8 to 26 weeks: mean values by week, 663 estimating, 13 estimations of, 138–139, 316–317 placenta:fetal-weight ratio by age, 152 see also birth weight, low weight/length [assets.cambridge.org] birth weight, growth retardation, severe microcephaly with a bird-headed like appearance, and mental retardation. [molsoft.com] Autosomal Recessive Mental Retardation Type 5 Infants with extremely low birth weight are at risk for intracranial hemorrhage and hypoglycemia resulting from a lack of hepatic glycogen storage. [emedicine.medscape.com] Low birth-weight, round-face, hypertelorism (wide-set eyes), low-set ears, epicanthal folds. [kumc.edu] Galloway-Mowat Syndrome Clinical Correlations: Infants have a low birth weight due to intrauterine growth retardation. [disorders.eyes.arizona.edu] Vaginitis BV also can cause adverse outcomes of pregnancy, including premature delivery and low-birth weight infants. [idph.state.il.us] In pregnancy, some types of vaginitis have been associated with premature births and babies with low birth weight. [cytologyassociates.com] If left untreated, BV may result in increased risk of pelvic inflammatory disease (PID), infertility, pre-term birth, premature rupture of membranes, low birth weight, intra-amniotic [idph.state.il.us] Bacterial Vaginosis The group with low birth weight had a mean (±SD) gestational age of 32.4±3.2 weeks and a mean birth weight of 1822±556 g. [doi.org] The women with bacterial vaginosis were more likely to be unmarried, to be black, to have low incomes, and to have previously delivered low-birth-weight infants. [ncbi.nlm.nih.gov] Other studies have also shown a possible link to miscarriages, low birth weight, and premature rupture of membranes. [americanpregnancy.org] Iron Deficiency Here's how: If your baby was born prematurely or at a low birth weight, talk with his doctor about iron supplements. [babycenter.com] In pregnant women, severe iron deficiency anemia has been linked to premature births and low birth weight babies. [mayoclinic.org] Between 9 and 24 months, all children are at high risk for anemia, but these babies are at highest risk: Premature and low-birth-weight babies age 2 months old and older. [babycenter.com] Congenital Deafness PERINATAL CAUSES► Ototoxic drugs► Radiation► Ultrasound► Maternal diabetes Hypoxia Hyperbilirubinemia Preterm delivery Low birth weight 9. [slideshare.net] Image source: Health.dngmedia.co.in Low Birth Weight Taking steps to prevent a low birth weight is also a good way to prevent congenital hearing loss. [speechbuddy.com] birth weight < 1500 g► Neonatal asphyxia► Hyperbilirubinaemia► Bacterial meningitis► Ototoxic drugs 11. [slideshare.net] Patent Ductus Arteriosus AIMS: To evaluate a three different PDA management approaches in very low birth weight (VLBW) infants. [ncbi.nlm.nih.gov] BACKGROUND: In very low birth weight infants, persistence of a patent ductus arteriosus results in morbidity and mortality. [ncbi.nlm.nih.gov] The aim of this study was to compare the lung function of very low birth weight (VLBW) infants after successful PDA treatment with a cyclooxygenase inhibitor or secondary [ncbi.nlm.nih.gov] Preterm Labor Low Birth Weight (LBW) and Very Low Birth Weight (VLBW) LBW refers to any baby that weighs less than 2,500 grams (about 5 pounds, 8 ounces). [medicinenet.com] Consumption is also known to help prevent premature delivery and low birth weight. Marijuana use can cause premature delivery, small size, and low birth weight. [diki.pl] Recently, it has been associated with adverse obstetric outcomes such as preterm delivery, low birth weight and premature rupture of membranes. [ncbi.nlm.nih.gov]
