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1,890 Possible Causes for Lower and Upper Limbs Affected, Myoclonic Jerking, Patient Appears Chronically Ill

  • Amyotrophic Lateral Sclerosis

    Approximately 2/3 of patients with ALS show the spinal form of the disease (limb injuries) characterised by weakness and muscular loss in lower and upper limbs.[icm-institute.org] […] and lower limbs.[ncbi.nlm.nih.gov] […] the disease (limb onset) and present with symptoms related to focal muscle weakness and wasting, in which onset of symptoms may start either distally or proximally in the upper[orpha.net]

  • Chronic Kidney Insufficiency

    Chronic kidney insufficiency affects a significant number of individuals in the developed countries, particularly the United States. The progressive nature of the disease and a substantial reduction in the quality of life over the period of time are the primary reasons why an early diagnosis is crucial. Anemia,[…][symptoma.com]

    Missing: Lower and Upper Limbs Affected
  • Neurologic Manifestation of Whipple Disease

    Article 117 Downloads 6 Citations Abstract Whipple’s disease is a rare, multisystem, infectious disorder caused by the bacterium Tropheryma whippelii . Patients with central nervous system (CNS) involvement may present in a variety of ways, including cognitive impairment, psychiatric manifestations, gaze palsies, upper[…][link.springer.com]

    Missing: Lower and Upper Limbs Affected
  • Whipple Disease

    Whipple disease is a systemic illness resulting from bacterial infection by a rare species of bacilli, Tropheryma whippleii. The gastrointestinal tract is the most frequently affected organ although the disease can spread to joints, central nervous system, eyes and rarely, heart. The disease is clinically presented with[…][symptoma.com]

    Missing: Lower and Upper Limbs Affected
  • Nocturnal Myoclonus Syndrome

    It has frequently been confused with, and should be clearly differentiated from, other normal jerking movements of sleep, such as partial myoclonic jerks and massive myoclonic[ncbi.nlm.nih.gov] Psychiatric illness such as depression and anxiety have been associated with chronic sleep loss 63,64 and appear to be more prevalent in patients with PLMS (and RLS.) 65,66[practicalneurology.com] Attacks may last several minutes to half an hour and more frequently affect the lower than upper limbs.[epilepsydiagnosis.org]

  • Disseminated Cryptococcosis

    Disseminated cryptococcosis is rare in immunocompetent hosts and hepatic manifestations as the presenting feature is further rare. We report a case of disseminated cryptococcosis with hepatic involvement as an initial manifestation in a previously healthy, immunocompetent adult. A young married female presented[…][ncbi.nlm.nih.gov]

    Missing: Lower and Upper Limbs Affected
  • Thallium Poisoning

    jerks, tremors, seizures, an impaired ability to coordinate voluntary movements (ataxia), and/or inability to stand or walk.[rarediseases.org] Distal motor weakness occurs, with the lower limbs more affected than the upper limbs.[emedicine.medscape.com] Decreased lower extremity strength with the lower limbs more affected than the upper limbs, hyperesthesia (especially of the soles of the feet), and decreased sensation to[emedicine.medscape.com]

  • Chronic Alcoholism

    During his admission he became drowsy and had myoclonic jerks. Both CT scan brain and lumbar puncture were normal.[ndt.oxfordjournals.org]

    Missing: Lower and Upper Limbs Affected
  • Restless Legs Syndrome

    Complying with an irresistible urge to move the affected limbs brings temporary relief. Sleep may become disrupted, resulting in excessive daytime hypersomnolence.[icd9data.com] A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.[icd10data.com] […] and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.[icd9data.com]

    Missing: Patient Appears Chronically Ill
  • Tay-Sachs Disease

    At 3 to 6 months decreased eye contact. twitchy eyes (myoclonic jerks). difficulty focusing on objects. excessive startling by sharp but not necessarily loud noises.[radiopaedia.org] At 3-6 months of age motor weakness, myoclonic jerks and an exaggerated startle reaction are usually the presenting features followed by developmental retardation and regression[genedx.com]

    Missing: Lower and Upper Limbs Affected