Autosomal Dominant Spastic Paraplegia Type 10
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[icd9data.com]
Pure HSPs are characterized by slowly progressive lower extremity spasticity and weakness, often associated with hypertonic urinary disturbances, mild reduction of lower extremity[medicbind.com]
Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified.[icd9data.com]
Autosomal Dominant Spastic Paraplegia Type 6
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[ebi.ac.uk]
Genetic counseling Hereditary Spastic Paraplegia (HSP) is a group of clinically and genetically heterogeneous disorders characterized by lower extremity spasticity and weakness[asperbio.com]
Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration[genecards.org]
Autosomal Dominant Spastic Paraplegia Type 4
[…] characterized predominantly by progressive lower extremity spasticity and weakness.[diseaseinfosearch.org]
lower extremity spasticity and weakness, with either autosomal dominant and recessive or X-linked pattern of inheritance.[link.springer.com]
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[ebi.ac.uk]
Muscle Spasticity
The three most common subtypes of spastic cerebral palsy are as follows: Hemiplegia — one side of the body is involved (usually the upper and lower extremity on the involved[chop.edu]
ITB has been found to be extremely effective in treating spasticity in the lower and upper extremities.[aans.org]
[…] side) Diplegia — the lower extremities are more involved than the upper extremities Quadriplegia — all four extremities are equally involved Spasticity inhibits normal muscular[chop.edu]
Autosomal Dominant Spastic Paraplegia Type 8
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[ebi.ac.uk]
Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration[genecards.org]
Clinical Features Symptoms depend on the type of HSP inherited Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction In the lower[slideshare.net]
X-Linked Spastic Paraplegia Type 2
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[connects.catalyst.harvard.edu]
(HSP) are a rare, heterogeneous group of inherited neurodegenerative diseases characterized by progressive lower extremity spasticity and weakness.[n.neurology.org]
The hereditary spastic paraplegias are a group of clinically and genetically diverse disorders characterized by progressive, usually severe, lower extremity spasticity; see[diseaseinfosearch.org]
Autosomal Dominant Spastic Paraplegia Type 31
[…] characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood[orpha.net]
[…] by insidiously progressive lower extremity spasticity.[neurology.org]
(SPG, HSP) are a large group of clinically and genetically diverse disorders characterized by progressive, usually severe, lower extremity spasticity and weakness.[flybase.org]
Autosomal Recessive Spastic Paraplegia Type 26
Genetic counseling Hereditary Spastic Paraplegia (HSP) is a group of clinically and genetically heterogeneous disorders characterized by lower extremity spasticity and weakness[asperbio.com]
Clinical Features Symptoms depend on the type of HSP inherited Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction In the lower[slideshare.net]
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[reference.md]
Autosomal Dominant Spastic Paraplegia Type 17
Genetic counseling Hereditary Spastic Paraplegia (HSP) is a group of clinically and genetically heterogeneous disorders characterized by lower extremity spasticity and weakness[asperbio.com]
Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration[genecards.org]
Clinical Features Symptoms depend on the type of HSP inherited Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction In the lower[slideshare.net]
Autosomal Recessive Spastic Paraplegia Type 18
Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[icd10data.com]
Clinical Features Symptoms depend on the type of HSP inherited Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction In the lower[slideshare.net]
extremity weakness and spasticity.[cags.org.ae]