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448 Possible Causes for Lower Extremity Spasticity

  • Autosomal Dominant Spastic Paraplegia Type 10

    Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[icd9data.com] Pure HSPs are characterized by slowly progressive lower extremity spasticity and weakness, often associated with hypertonic urinary disturbances, mild reduction of lower extremity[medicbind.com] Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified.[icd9data.com]

  • Autosomal Dominant Spastic Paraplegia Type 6

    Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[ebi.ac.uk] Genetic counseling Hereditary Spastic Paraplegia (HSP) is a group of clinically and genetically heterogeneous disorders characterized by lower extremity spasticity and weakness[asperbio.com] Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration[genecards.org]

  • Autosomal Dominant Spastic Paraplegia Type 4

    […] characterized predominantly by progressive lower extremity spasticity and weakness.[diseaseinfosearch.org] lower extremity spasticity and weakness, with either autosomal dominant and recessive or X-linked pattern of inheritance.[link.springer.com] Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[ebi.ac.uk]

  • Muscle Spasticity

    The three most common subtypes of spastic cerebral palsy are as follows: Hemiplegia — one side of the body is involved (usually the upper and lower extremity on the involved[chop.edu] ITB has been found to be extremely effective in treating spasticity in the lower and upper extremities.[aans.org] […] side) Diplegia — the lower extremities are more involved than the upper extremities Quadriplegia — all four extremities are equally involved Spasticity inhibits normal muscular[chop.edu]

  • Autosomal Dominant Spastic Paraplegia Type 8

    Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[ebi.ac.uk] Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration[genecards.org] Clinical Features  Symptoms depend on the type of HSP inherited  Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction  In the lower[slideshare.net]

  • X-Linked Spastic Paraplegia Type 2

    Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[connects.catalyst.harvard.edu] (HSP) are a rare, heterogeneous group of inherited neurodegenerative diseases characterized by progressive lower extremity spasticity and weakness.[n.neurology.org] The hereditary spastic paraplegias are a group of clinically and genetically diverse disorders characterized by progressive, usually severe, lower extremity spasticity; see[diseaseinfosearch.org]

  • Autosomal Dominant Spastic Paraplegia Type 31

    […] characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood[orpha.net] […] by insidiously progressive lower extremity spasticity.[neurology.org] (SPG, HSP) are a large group of clinically and genetically diverse disorders characterized by progressive, usually severe, lower extremity spasticity and weakness.[flybase.org]

  • Autosomal Recessive Spastic Paraplegia Type 26

    Genetic counseling Hereditary Spastic Paraplegia (HSP) is a group of clinically and genetically heterogeneous disorders characterized by lower extremity spasticity and weakness[asperbio.com] Clinical Features  Symptoms depend on the type of HSP inherited  Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction  In the lower[slideshare.net] Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[reference.md]

  • Autosomal Dominant Spastic Paraplegia Type 17

    Genetic counseling Hereditary Spastic Paraplegia (HSP) is a group of clinically and genetically heterogeneous disorders characterized by lower extremity spasticity and weakness[asperbio.com] Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration[genecards.org] Clinical Features  Symptoms depend on the type of HSP inherited  Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction  In the lower[slideshare.net]

  • Autosomal Recessive Spastic Paraplegia Type 18

    Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.[icd10data.com] Clinical Features  Symptoms depend on the type of HSP inherited  Main feature progressive spasticity in the lower limbs, due to pyramidal tract dysfunction  In the lower[slideshare.net] extremity weakness and spasticity.[cags.org.ae]

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