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19 Possible Causes for Lower Leg Pain, Vitreous Floaters

  • Hereditary ATTR Amyloidosis

    BACKGROUND: Patisiran is an investigational RNA interference (RNAi) therapeutic in development for the treatment of hereditary ATTR (hATTR) amyloidosis, a progressive disease associated with significant disability, morbidity, and mortality. METHODS: Here we describe the rationale and design of the Phase 3 APOLLO[…][ncbi.nlm.nih.gov]

  • Spondylitis

    Aching in the lower back which can disrupt sleep. Pain radiating down the legs and into the groin. Pain is worse during and after rest e.g. in the mornings.[sportsinjuryclinic.net] Symptoms include floaters and visual loss if the choroiditis involves the macular area.[medical-dictionary.thefreedictionary.com] Managing your weight can help you reduce strain on your lower back, hips, legs and feet.[arthritis.org.au]

  • Ankylosing Spondylitis

    Aching in the lower back which can disrupt sleep. Pain radiating down the legs and into the groin. Pain is worse during and after rest e.g. in the mornings.[sportsinjuryclinic.net] Symptoms include floaters and visual loss if the choroiditis involves the macular area.[medical-dictionary.thefreedictionary.com] Common symptoms may include: Stiffening and pain (arthritis) of the: Lower back Sacroiliac joint, where the back and hip meet, possibly radiating down the legs Pain that is[cancercarewny.com]

  • Multiple Sclerosis

    […] of the arms, hands, feet, ankles, or lower legs muscle cramps stomach pain diarrhea heartburn constipation gas weight gain or loss depression night sweats painful, irregular[nlm.nih.gov] , vitreous reaction Fluorescein angiography, B-scan ultrasonography of orbits Autoimmune optic neuropathy (Similar to CRION) Steroid responsive Skin biopsy for immunoglobulin[emedicine.com] […] in the back, neck, or any other part of the body severe headache loss of appetite diarrhea nausea vomiting weight gain swelling of the hands, feet, ankles, or lower legs[nlm.nih.gov]

  • Amyloidosis

    , numbness, and tingling in your hands, feet, and lower legs dizziness when standing up nausea diarrhea inability to feel cold or heat General symptoms that can occur include[healthline.com] Patients may also experience vision problems including dry eyes, blurred vision and eye floaters (vitreous floaters).[fda.gov] The Nervous System Amyloid deposits can affect the nerves of the hands, feet and lower legs and may cause pain, numbness and tingling.[amyloidosis.org]

  • Panuveitis

    History In addition to the right eye pain, the patient reported pain along her entire left leg and lower back for about one year.[retina-specialist.com] Floaters or flashes of light may be signs of vitreous detachment or a retinal detachment.[preventblindness.org] A few tiny keratic precipitates and cells in the aqueous humor and vitreous body, with some floaters, predominantly in the posterior vitreous, were present in the left eye[journals.lww.com]

  • Retinal Phlebitis

    This can cause pain, swelling, fevers or chills. Early signs can be a brown staining of the skin on the lower legs. Unchecked the clots can cause a stroke or even death.[secretenergy.com] (indicates significant migration of leukocytes to vitreous) • Photopsia & reduced color vision (less common but present in vasculitis surrounding macula) • Central or Para[slideshare.net] lowered rather than elevated Low-grade fever Swelling, pain or skin irritation caused by infection Usually, these symptoms develop slowly.[draxe.com]

  • Hereditary Amyloidosis with Primary Renal Involement

    […] in the lower extremities; cough and breathing problems when lying flat, shortness of breath on climbing stairs or an incline, and dizziness on standing, swelling of the legs[tuftsmedicalcenter.org] Symptoms include floaters, blurry vision or glare, or patients may be asymptomatic.[healio.com] […] and weight loss, and may also include a feeling of fullness in the stomach, limiting the size of meals one can eat comfortably; numbness, tingling, burning or bursts of pain[tuftsmedicalcenter.org]

  • Stickler Syndrome

    There it goes – now the pain has grown, making not only my knee, but the whole lower half of my leg now in pain. I’m not doing anything.[themighty.com] Vitreous abnormalities present as floaters, wherein the child sees small floating objects in front of his/her eyes. These floaters affect the child’s vision.[medindia.net] Next will be my ankles, now that my whole lower half is “locked up” or “frozen.” My already bad limp is worse, and much, much more painful.[themighty.com]

  • Disseminated Toxoplasmosis

    Evolution The patient worsened with fever and neurological impairment, with right leg paralysis, positive meningeal signs and abdominal pain as a reflection of intestinal[acmicrob.com] Presentation varies: Possible symptoms are reduced visual acuity and floaters.[patient.info] On the second day after admission, consciousness lowered, she only answered to painful stimuli and showed right mydriasis and low reactive left pupil.[acmicrob.com]

Further symptoms