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249 Possible Causes for Lower Limb Hyperreflexia

  • Autosomal Recessive Spastic Paraplegia Type 27

    limb spasticity lower limb hyperreflexia extensor plantar responses normal muscle strength more Genitourinary Bladder: spastic/hyperactive bladder Clinical features from[] There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign.[] limb hyperreflexia 59 32 hallmark (90%) Very frequent (99-80%) HP:0002395 7 impaired vibration sensation at ankles 59 32 hallmark (90%) Very frequent (99-80%) HP:0006938[]

  • Autosomal Recessive Ataxia Type Beauce

    limb hyperreflexia Action tremor Head tremor Abnormality of eye movement Behavioral abnormality Difficulty walking Motor delay Slow saccadic eye movements Cognitive impairment[] Progressive cerebellar ataxia Autosomal recessive inheritance Dysmetric saccades Truncal ataxia Intention tremor Babinski sign Rare Symptoms - Less than 30% cases Seizures Lower[] […] may also develop some of the following symptoms: Common Symptoms - More than 50% cases Slow progression Uncommon Symptoms - Between 30% and 50% cases Tremor Adult onset Hyperreflexia[]

  • Hereditary Motor and Sensory Neuropathies

    Some MFN2 mutations produce optic atrophy and CMT neuropathy (HMSN6), while others display a combination of axonal neuropathy and lower limb hyperreflexia (HMSN V) (see Table[]

  • Neuroleptic Malignant Syndrome

    Conversely, patients with serotonin syndrome are typically hyperkinetic, with tremors, clonus, and prominent lower limb hyperreflexia.[]

  • Spinocerebellar Ataxia Type 22

    However, other common SCA28 features like pyramidal tract signs (lower limb hyperreflexia, positive Babinski sign), ophthalmoparesis or ptosis were absent.[] […] ataxia Dysarthria Slow and lower limb hyperreflexia Opthalmoplegia Patients with shorter disease duration - Gaze-evoked nystagmus Patients with longer disease duration -[] Neurological examination showed cerebellar ataxia, mild Parkinsonian features with predominant bradykinesia, polyneuropathy of the lower limbs, and cognitive decline.[]

  • Congenital Muscular Dystrophy Type 1D

    Mutation of the LARGE gene is the rarest of the six known genetic causes of α-dystroglycanopathy. We report further a family with MDC1D due to a complex genomic rearrangement that was not apparent on standard sequencing of LARGE. Two sisters in a consanguineous family had moderate mental retardation and[…][]

  • Cervical Myelopathy

    limb spasticity, hyperreflexia, and T1 hypointensity were associated with greater SCR ( P .05).[] MSCC ( P .05); broad-based, unstable gait, impairment of gait, and Hoffmann sign were associated with greater MCC ( P .05); and numb hands, Hoffmann sign, Babinski sign, lower[]

  • Hepatitis C Virus

    Neurological examination disclosed a grade 4 spastic paraparesis, lower limb hyperreflexia, right positive Hoffmann sign, bilateral Babinski sign and spastic gait only possible[]

  • Cervical Spondylosis

    Eleven patients (58%) had lower limb hyperreflexia or Babinski sign.[] In the control group, five patients (38%) showed hyperreflexia of the lower limbs and Babinski sign.[]

  • Autosomal Dominant Spastic Paraplegia Type 29

    Related phenotypes are lower limb hyperreflexia and babinski sign[] […] spasticity Commonly - More than 50% cases Impaired proprioception Not very common - Between 30% and 50% cases Hiatus hernia Commonly - More than 50% cases Lower limb hyperreflexia[] Showing of 25 80%-99% of people have these symptoms Babinski sign 0003487 Lower limb hyperreflexia Overactive lower leg reflex 0002395 30%-79% of people have these symptoms[]

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