8,449 Possible Causes for Lung Biopsy showing Multinucleated Giant Cells

  • Upper Respiratory Infection

    A recent study 54 showed that lower vitamin D levels correlated with higher risk of URIs; particularly in patients with asthma and chronic obstructive lung disease.[clevelandclinicmeded.com] Lower respiratory infections affect the lungs and airways.[vitamindcouncil.org] However, polysaccharide antigens do not elicit an immune response in young children but, by introducing a protein conjugate coupled to capsular polysaccharide, T-cell help[bmb.oxfordjournals.org]

  • Acute Gastroenteritis

    Akech et al. (2010) reported the need for furosemide or the diagnosis of pulmonary oedema as defined by crepitations in both lungs in the presence of hypoxaemia (low oxygen[wellcomeopenresearch.org] In the malnourished children, haemodynamic parameters were abnormal when compared with convalescent patients: red cell volume and total blood volumes were 51% and 66%; cardiac[wellcomeopenresearch.org] Table 2 and Table 3 show the setting, methodology and features of the included studies and their results.[wellcomeopenresearch.org]

  • Granulomatous Lung Disease

    Presence of granulomas in a lung biopsy or at autopsy is a relative common finding.[histopathology-india.net] […] disease -Stage 3: parenchymal lung disease only -Stage 4: fibrosis and cystic changes -Bilateral hilar adenopathy most common finding -Upper and mid lung shows coarse reticular[brainscape.com] Presentation on theme: "GRANULOMATOUS LUNG DISEASE & INTERSTITIAL LUNG DISEASE[slideplayer.com]

  • Berylliosis

    It is marked by the presence of large amounts of macrophages, the body’s scavenger cells, which may fuse to form giant cells in a granuloma.[healthhype.com] It is characterised by the development of granulomatous inflammation secondary to a cell-mediated immune response to beryllium.[radiopaedia.org] The research shows that a single amino acid change present in one lung protein, HLA-DP2, creates a pocket able to bind beryllium and sodium ions simultaneously and trigger[spectroscopynow.com]

  • Measles Pneumonia

    We reported a measles pneumonia case in a previously healthy adolescent girl who had a fatal pneumonia by giant cells demonstrated by open lung biopsy.[ncbi.nlm.nih.gov] Synopsis Warthin-Finkedley cells Multinucleated giant cells with intranuclear inclusion bodies were revealed in the transbronchial lung biopsy (TBLB) Variants familial cases[humpath.com] (B) the pathogenesis The main pathological changes of measles are extensive cell fusion to form multinucleated giant cells.[healthfrom.com]

  • Sarcoidosis

    Diagnosis usually requires chest x-ray, usually computed tomography, and analysis of a sample of tissue (biopsy), usually from the lungs.[msdmanuals.com] These tests can show whether sarcoidosis is affecting your lungs.[nhlbi.nih.gov] A biopsy, either by bronchoscopy or by a surgical lung biopsy — to determine if granulomas are present.[upmc.com]

  • Wegener Granulomatosis

    , multinucleated giant cells, as part of poorly formed granulomas, surrounded by pallisading histiocytes and giant cells with central necrosis Destructive leukocytic angiitis[pathologyoutlines.com] […] or bronchial stenosis. - The earliest mucosal lesions consist of foci of necrotising inflammation and ulceration with occasional multinucleate histiocytic giant cells. -[histopathology-india.net] Granulomatous lesions are built up by CD4þ and CD8þ T cells, CD28 T cells, histiocytes, CD20þ B lymphocytes, neutrophil granulocytes, macrophages, and multinucleated giant[emedmd.com]

  • Pulmonary Sarcoidosis

    BALF cells, mucosal biopsies and PB were processed as previously described [ 21 ].[respiratory-research.biomedcentral.com] […] heart, eye, kidney, liver, skin Noncaseating granulomas Tight, well-formed granulomas Composed of epithelioid histiocytes and/or multinucleated giant cells Sharply circumscribed[surgpathcriteria.stanford.edu] In contrast to normal control cells, the lung T-lymphocytes of patients with sarcoid release the mediator, monocyte chemotactic factor, that probably contributes to the pathogenesis[annals.org]

  • Maple Bark Strippers' Lung

    Granulomas – Bronchiolo-centric – Non-caseating – Loose (poorly-formed) aggregation of epithelioid histiocytes – And/Or Single interstitial multinucleated giant cellsGiant[slideshare.net] After recruitment and activation, macrophages develop into epitheliod and multinucleated giant cells [25].[worldallergy.org] The cells in your body need oxygen to work and grow.[coding-pro.com]

  • Pulmonary Tuberculosis

    Figure 2 In patient No. 8, the HRCT showed diffuse ground-glass attenuation and micronodules over interstitium; open lung biopsy revealed multiple caseating granuloma distributed[nature.com] The detailed section of the diagram shows typical features of tuberculous granuloma: central caseous necrosis surrounded by epithelioid cells, multinucleated giant cells,[medical-dictionary.thefreedictionary.com] With meningitis, the scan may be normal but can also show diffuse oedema or obstructive hydrocephalus.[southsudanmedicaljournal.com]

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