The helper T cellsshow a strong proliferative reaction on being exposed to beryllium. … The lavage shows >20% lymphocytes. 6 high-quality transbronchial biopsy samples should be collected to get a optimum result. … In certain individuals a lungbiopsy might be necessary to check for granulations as well as beryllium deposits.
The core of the latter is composed of Epithelioid histiocytes and multinucleatedgiantcells while the external wall consist of T lymphocytes. … Immune mediating cells such as giantcells, compose the core, surrounded by an outer rim of T lymphocytes will start migrating to the area in order to help in the normal healing … Schaumann bodies seen in sarcoidosis are calcium and protein inclusions inside of Langhans giantcells as part of a granuloma.
In this condition, radiographic images of the lungs do not show any alterations but the tuberculin skin test shows positive results. … It does survive inside the phagosome, multiplies and eventually kills its host cell. … HIV patients may not show typical pulmonary TB symptoms due to their impaired immune system.
On rare occasions, thoracoscopic lungbiopsy is required. … In most cases, either the lungs or the kidneys are favorable sites for obtaining biopsy material. … Typically, granulomas form with epitheloid and giantcells, while the presence of various leukocytes, including neutrophils, lymphocytes, and eosinophils, has been observed … 
The doctor will obtain a chest X-ray, which will show specific collections of cells. … A key radiographic feature of sarcoidosis is the non-caseating granuloma with giantcells. … Pulmonary sarcoidosis is characterized by the presence of noncaseating granulomas, which are abnormal collections of cells in the lungs.