Lung Function Impairment: Causes & Reasons

Possible Causes for Lung Function Impairment

Etiology Pulmonary disease in PCD is related to defects in lung defense mechanisms due to abnormal ciliary structure and function with impaired mucociliary clearance. [orpha.net]

VO 2peak and association with lung function parameters The question at hand was whether reduced aerobic fitness was related to impaired lung function. [journals.plos.org]

Impaired lung function [ 16 ] and radiological evidence of bronchiectasis can already be evident in infancy [ 17 ]. [err.ersjournals.com]

Pneumonia

[…] and compression of contralateral lung, trachea, heart, and superior vena cava; → impaired respiratory function, reduced venous return to the heart and reduced cardiac output [amboss.com]

Aspiration pneumonia most often develops due to micro-aspiration of saliva, or bacteria carried on food and liquids, in combination with impaired host immune function.[28] [en.wikipedia.org]

Infection‐associated exacerbations required longer hospitalisation and resulted in greater impairment of lung function than exacerbations in which no infection was present [doi.org]

Spinal Cord Compression

Consultant Radiation Oncologist Published on Oct 26, 2013 Malignant Spinal Cord Compression(Metstatic aspects in detail) 1. Maliganant Spinal Cord Compression Dr Sasikumar Sambasivam Dept. Of Palliative Medicine 2. Intra medullary Intradural Extramedullary Extradural Compressive Myelopathy Compressive Myelopathy 3.[…] [slideshare.net]

Mucopolysaccharidosis Type 6

Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome) in the pre-Columbian culture of Colombia Harry Pachajoa, Carlos Armando Rodriguez Full Text: PDF(EN) PDF(ES) HTML Abstract Mucopolysaccharidosis type VI or Maroteaux Lamy syndrome is an autosomal recessive lysosomal storage disorder resulting from a[…] [colombiamedica.univalle.edu.co]

Psittacosis

A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with[…] [ncbi.nlm.nih.gov]

Pleural Fibrosis

function impairment in sheet metal workers. [cdc.gov]

Asbestos-induced pleural fibrosis and impaired lung function. [cdc.gov]

Occasionally, one of the lungs becomes encased with a thick fibrous layer that limits the ability to expand and take in oxygen and impairs lung function. [msdmanuals.com]

Decreased Diffusion Capacity of the Lung

CONCLUSIONS: Thus, in sarcoidosis, densitometric parameters reflect restrictive lung function impairment. [ncbi.nlm.nih.gov]

Patients with severe asthma tend to have impaired lung function despite the high-intensity treatment. Aims. [erj.ersjournals.com]

Conclusions: PFTs assist in the diagnosis of lung disease by describing and quantifying the impairment in function. [chw.org]

Byssinosis

For those individuals who are misdiagnosed or untreated, the chronic exposure to cotton can lead to lung fibrosis and impaired lung function. [statpearls.com]

Patients misdiagnosed or untreated can experience lung fibrosis and impaired lung function. [narayanahealth.org]

However, with continued exposure, lungs can become permanently damaged and lung function permanently impaired. [oxygenconcentratorstore.com]

Restrictive Lung Disease

Abstract Purpose: The aim of this study was to ascertain whether symptoms of respiratory disorders and lung functional impairments are associated with occupational inhalation [joi.jlc.jst.go.jp]

Restrictive lung disease and the presence of respiratory symptoms in the absence of lung function impairment were also associated with an increased risk of this outcome (OR [ncbi.nlm.nih.gov]

These pathophysiologic changes help explain why functional disability in these patients is often out proportion to the impairment in lung function. [ncbi.nlm.nih.gov]

Nitrogen Tetroxide Exposure

Some cross sectional studies in adults and children have shown associations between ambient NO 2 concentrations and impaired lung function (93, 236, 392, 401, 402) but it [greenfacts.org]

Effects of long-term or repeated exposure The substance may have effects on the lungs. This may result in impaired functions and decreased resistance to infection. [inchem.org]

function was not impaired based on a normal result on lung function tests. [caselaw.findlaw.com]

Copper Allergy

Información de seguridad Taking more than 400 µg of selenium per day from all sources should only be done under the guidance of a healthcare professional. Ingredientes Serving Size: 1 capsule, Servings Per Container: 150, Amount per serving: Vitamin A (as 1000 IU of Retinyl Palmitate) 300 mcgRAE, Vitamin C (as[…] [amazon.com]

Sclerodermatomyositis

Similar articles Sclerodermatomyositis with megacolon, small-bowel involvement and impaired lung function. Srinivas V. Srinivas V. Proc R Soc Med. 1976 Apr;69(4):263-4. [pubmed.ncbi.nlm.nih.gov]

Exposure to Cement Dust

Cement dust causes lung function impairment, chronic obstructive lung disease, restrictive lung disease, pneumoconiosis and carcinoma of the lungs, stomach and colon. [ncbi.nlm.nih.gov]

On his side, Mwanza’s Regional Medical Officer (RMO), Dr Leonard Subi, the cement dust causes lung function impairment and chronic obstructive lung diseases. [thecitizen.co.tz]

Lung functions in cement mill workers were significantly impaired and results show a long term duration response effect of years of exposure to cement dust on lung functions [ncbi.nlm.nih.gov]

Pulmonary Alveolar Proteinosis with Hypogammaglobulinemia

[from OMIM] From HPO Respiratory insufficiency MedGen UID: 11197 •Concept ID: C0035229 • Pathologic Function Impairment of gas exchange within the lungs secondary to a disease [ncbi.nlm.nih.gov]

Magg et al. (2021) determined that the disorder results from a gain-of-function effect that particularly affects B cells and monocytes. [ncbi.nlm.nih.gov]

Paucigranulocytic Asthma

function impairment [18]. [erj.ersjournals.com]

[…] challenge and were divided into a training cohort (n=129, baseline FEV1 95% predicted) and a validation cohort (n=141, baseline FEV1 91% predicted), indicating no substantial lung [erj.ersjournals.com]

Baritosis

Inhaled barium particles can lie in the lungs for years without producing symptoms or causing any impairment in lung function 3. [radiopaedia.org]

In fact, abnormal clinical findings accompanied by an inability to work and frequent leave of absence, as well as impaired lung function, is never reported if baritosis alone [symptoma.com]

Inhalation of Nitrogen Dioxide

Some cross sectional studies in adults and children have shown associations between ambient NO 2 concentrations and impaired lung function (93, 236, 392, 401, 402) but it [greenfacts.org]

Effects of long-term or repeated exposure The substance may have effects on the lungs. This may result in impaired functions and decreased resistance to infection. [inchem.org]

Several new longitudinal cohort studies have also shown associations between outdoor NO 2 concentrations and impaired growth in lung function (22, 23, 24, 235) but this effect [greenfacts.org]

Idiopathic Pulmonary Fibrosis

He received an 18-month N-acetylcysteine monotherapy but had no improvement in lung function. IPF with mild impairment in lung function was diagnosed. [ncbi.nlm.nih.gov]

Progressive and irreversible lung functional impairment leads to chronic respiratory insufficiency with a severely impaired quality of life. [dovepress.com]

Long-term treatment with pirfenidone resulted in similar rates of decline in lung function in patients with more severe lung function impairment compared with patients with [err.ersjournals.com]

Diatomaceous Earth Pneumoconiosis

Non-fibrogenic dusts evoke a tissue reaction in lungs characterized by minimal fibrotic reaction and absence of lung function impairment. [iloencyclopaedia.org]

In general, the reaction of lung tissue to the presence of dust varies with different dusts. [iloencyclopaedia.org]

Pneumoconiosis

However, medical literature generally holds that simple coal worker's pneumoconiosis (CWP) is not associated with lung function impairment. [ncbi.nlm.nih.gov]

He showed severe lung function impairment, a cavity in his right upper lung lobe, nodular and irregular opacities, fibrotic pleural changes and emphysema. [ncbi.nlm.nih.gov]

function impairment and a minimum of 20 years of underground exposure to coal dust. [patient.info]

Pulmonary Bullous Emphysema

(13), but there is no clear guidelines on the severely impaired lung function. [jtd.amegroups.com]

Pulmonary function tests revealed mild restrictive disease and a severe reduction in diffusion capacity. [karger.com]

Asbestosis

Sputum cytology and IL-8 in serum and sputum were related to lung function impairment. [ncbi.nlm.nih.gov]

Additionally, mediastinal lymph node enlargement is associated with severity of lung function impairment, risk of respiratory and all-cause hospitalization, and decreased [ajrccm.atsjournals.org]

MARCH 2019 AnnalsATS Mediastinal lymph node enlargement is associated with survival in patients with interstitial lung disease and might be useful for risk stratification. [ajrccm.atsjournals.org]

Pulmonary Histiocytosis X

Laboratory tests were non-specifically altered, lung function was impaired. [ncbi.nlm.nih.gov]

Laboratory tests were altered nonspecifically, and lung function was impaired. [ncbi.nlm.nih.gov]

Lung function tests - may show impaired diffusing capacity. CT scan - may show typical changes of pulmonary LCH. Bronchoalveolar lavage. [patient.info]

Primary Ciliary Dyskinesia

function impairment with increased age and patient views on diagnostic testing. [beatpcd.org]

Lung auscultation revealed end-inspiratory coarse crackles. Pulmonary function tests demonstrated mild obstructive ventilation functional impairment. [ncbi.nlm.nih.gov]

Recurrent lung infections lead to impaired lung function and possibly poor oxygenation. Sinus infections, poor sense of smell and eye anomalies are common. [mun-h-center.se]

Chronic Obstructive Pulmonary Disease

Abstract Lung cancer and chronic obstructive pulmonary disease have shared etiology, including key etiological changes (e.g., DNA damage and epigenetics change) and lung function [ncbi.nlm.nih.gov]

Acute exacerbations are associated with more rapid decline in lung function and impaired quality of life and are the major causes of morbidity and mortality in COPD. [ncbi.nlm.nih.gov]

function becomes more impaired. [jamanetwork.com]

Combined Oxidative Phosphorylation Defect Type 37

Respiratory insufficiency MedGen UID: 11197 •Concept ID: C0035229 • Pathologic Function Impairment of gas exchange within the lungs secondary to a disease process, neoplasm [ncbi.nlm.nih.gov]

Honeycomb Lung

For major breathing problems, oxygen therapy may be necessary if the disease continues to worsen and lung function is impaired. [healthcentral.com]

Writing in a paper, they said: 'Electronic cigarettes immediately impairs lung function, lasting for less than 30 minutes after smoking.' [dailymail.co.uk]

Symptoms and signs of interstitial lung disease occur because the damage to the interstitium of the lung impairs breathing function. [medicinenet.com]

Suberosis

Restrictive defect was the most frequent pattern of lung function impairment, and more severe in BFD. [ncbi.nlm.nih.gov]

Bentonite Pneumoconiosis

In cases of long-term exposure to externally high levels of dust, complicated pneumoconiosis with lung function impairment may occur. [yellowstarmining.co.za]

Severe functional impairment occurs in the late stages of conglomerate silicosis, and respiratory insufficiency - its ultimate consequence may progress along with radiographic [digitalfire.com]

HL1115 Influences on Health at Work 50 51 Restrictive flow impairment, such as observed in interstitial lung disease is indicated by a decrease in volume. [slideplayer.com]

Pulmonary Fibrosis

Progressive and irreversible lung functional impairment leads to chronic respiratory insufficiency with a severely impaired quality of life. [dovepress.com]

Lung function test revealed mild mixed ventilatory impairment with severe diffusion defect. [ncbi.nlm.nih.gov]

Function Impairment Completed NCT02802345 Phase 3 Nintedanib;Placebo;Sildenafil 34 Open-Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed [malacards.org]