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87 Possible Causes for Lung Function Testing Abnormal, T Cell Activation Increased, X-Ray Abnormal

  • Asthma

    There are increased numbers of activated eosinophils, CD25-positive T lymphocytes, and immature macrophages with the phenotypic characteristics of blood monocytes.[ncbi.nlm.nih.gov] (a) The chest x-ray shows an abnormal distension of the fundus of the stomach.[ncbi.nlm.nih.gov] Pulmonary function tests abnormalities included: high fractional exhaled nitric oxide (FeNO), high lung clearance index (LCI), and elevated diffusing capacity of the lungs[ncbi.nlm.nih.gov]

  • Chronic Obstructive Pulmonary Disease

    Cytokines are secreted from the stimulated Tcells to further increase immune activity.[doi.org] Chest CT may reveal abnormalities that are not apparent on the chest x-ray and may also suggest coexisting or complicating disorders, such as pneumonia, pneumoconiosis, or[merckmanuals.com] Findings on a chest x-ray or computed tomography (CT) of the chest may also help in diagnosis of emphysema and sometimes chronic bronchitis.[merckmanuals.com]

  • Allergic Asthma

    It is associated with increased IgE, mast cell activation, airway hyperresponsiveness (AHR), mucus overproduction and remodeling of the airways.[ncbi.nlm.nih.gov] Previously, this pathological trait has been associated with T helper type 2 (Th2) cells.[ncbi.nlm.nih.gov]

  • Acute Respiratory Distress Syndrome

    Role of T and B Cells in ARDS After APC activation, the cells recruit circulating T and B cells to cause inflammatory cascades.[mdpi.com] Chest X-rays showed abnormalities in 60–100% of the patients [ 16 ].[em-consulte.com] Severe pneumonia Coughing and purulent sputum, Consolidation foci in chest x-ray Pulmonary thromboembolism "Almost" normal chest x-ray with refractory hypoxemia Mixed Severe[xlung.net]

  • Interstitial Lung Disease

    B-cell aggregates, activated T-cells and mature dendritic cells have been reported in the IPF lung, increasing the likelihood of antigen presentation activity [ 52, 53 ].[err.ersjournals.com] If there are risk factors for ILD or abnormal X-ray findings, your doctor will likely perform a high resolution CT.[arthritis.org] Patient-centred measures, pulmonary function tests and the single breath carbon monoxide diffusing capacity of the lung (DLco) were also obtained.[ncbi.nlm.nih.gov]

  • Secondary Pulmonary Interstitial Fibrosis

    Increase of activated T-cells in BAL fluid of Japanese patients with bronchiolitis obliterans organizing pneumonia and chronic eosinophilic pneumonia.[appliedradiology.com] If there are risk factors for ILD or abnormal X-ray findings, your doctor will likely perform a high resolution CT.[arthritis.org] Diagnosis typically requires additional tests, including the following: Chest x-ray is the first step that can indicate abnormalities as well as how the disease is progressing[myositis.org]

  • Pulmonary Fibrosis

    PubMed Google Scholar Kotani I, Sato A, Hayakawa H, Urano T, Takada Y, Takada A: Increased procoagulant and antifibrinolytic activities in the lungs with idiopathic pulmonary[respiratory-research.biomedcentral.com] After detection of lung fibrosis in chest X-ray, he was put on the antioxidant and immunosuppressive therapy, but expired almost 20 h after admission.[ncbi.nlm.nih.gov] The chest X-ray may or may not be abnormal, but a high resolution CT scan will often show abnormalities.[breathingmatters.co.uk]

  • Granulomatosis with Polyangiitis

    RESULTS: Frequency of CD4 CD8 double-positive T-cells was increased within the total CD3 T-cell population in GPA, but no difference was detected between patients with active[ncbi.nlm.nih.gov] Chest x-rays may be abnormal, either showing diffuse disease (67%) or isolated areas (58%).[dermnetnz.org] Pulmonary function tests are frequently altered, showing a reduction in the diffusion capacity for carbon monoxide, which can be associated with obstructive abnormalities[ncbi.nlm.nih.gov]

  • Cystic Fibrosis

    Phenotypes include augmented IgE production in response to pathogens, altered Ca2 flux in response to T-cell receptor activation, and increased IL-13 secretion. [ PMC free[ncbi.nlm.nih.gov] He was seen in the emergency department and chest x-rays showed no abnormalities.[ncbi.nlm.nih.gov] Any abnormalities in these functions may indicate cystic fibrosis.[healthline.com]

  • Chronic Eosinophilic Pneumonia

    Two-color analysis of T-cell subsets revealed that CD3 HLA-DR cells (activated T cell) in BALF of patients with BOOP and CEP increased significantly compared with volunteers[ncbi.nlm.nih.gov] Complete resolution of symptoms and x-ray abnormalities occurs within 14 days in most patients and by 1 mo in almost all.[merckmanuals.com] Lung function tests during the acute illness showed volume restriction or gas transfer defects or both in two cases.[thorax.bmj.com]

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