Create issue ticket

569 Possible Causes for Lupus Nephritis, Thrombocytopenia

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] What is lupus nephritis? There are two types of lupus.[kidney.org] A 40-year-old woman with systemic lupus erythematosus (SLE) presented with high-grade fever and severe thrombocytopenia.[ncbi.nlm.nih.gov]

  • Atypical Hemolytic Uremic Syndrome

    A 28-day-old female presented with gross hematuria and hypertension. aHUS was suspected based on anemia with schistocytes, thrombocytopenia, low C3, and acute kidney injury[ncbi.nlm.nih.gov] She was diagnosed with systemic lupus erythematosus (SLE) and class V lupus nephritis.[ncbi.nlm.nih.gov] Investigations revealed hemolytic anemia, thrombocytopenia, renal impairment, and a low serum C3, leading to the diagnosis of aHUS.[ncbi.nlm.nih.gov]

  • Gaucher Disease

    Medical examination showed slight splenomegaly (250 62 mm), thrombocytopenia (platelets 51 109/L), anemia (Hb levels 107 g/L), and β-glucocerebrosidase activity (GBA) in leukocytes[ncbi.nlm.nih.gov] We reported the immunological evaluation of a patient with GD and lupus nephritis.[ncbi.nlm.nih.gov] Gaucher disease is a common inborn error of metabolism leading to widespread chronic inflammation and often thrombocytopenia.[ncbi.nlm.nih.gov]

  • Thrombotic Thrombocytopenic Purpura

    Unfortunately, there is no clear guidance for when thrombocytopenia is refractory for a prolonged period of time.[ncbi.nlm.nih.gov] The definitive diagnosis was lupus nephritis with TTP.[biblat.unam.mx] Careful analysis revealed the development of heparin-induced thrombocytopenia (HIT) that precluded platelet count (PLT) normalization.[ncbi.nlm.nih.gov]

  • Nephrotic Syndrome

    We herein describe a case of nephrotic syndrome with thrombocytopenia, lymphadenopathy, systemic inflammation, splenomegaly, kidney enlargement, and progressive renal insufficiency[ncbi.nlm.nih.gov] Renal histology showed International Society of Nephrology/Renal Pathology Society Class II lupus nephritis.[ncbi.nlm.nih.gov] Thrombocytopenia finally led to uncontrollable gastrointestinal bleeding as the direct cause of the patient's death.[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    The aim of our study was to analyze the association of immune thrombocytopenia (ITP) with chronic myelomonocytic leukemia (CMML).[ncbi.nlm.nih.gov] Most common causes include allergic reactions (eg, drug-induced), infections, auto-immune and infiltrative processes (eg, lupus nephritis and sarcoidosis), inflammatory disease[dovepress.com] thrombocytopenia").[ncbi.nlm.nih.gov]

  • Eclampsia

    Thrombocytopenia-absent radius (TAR) syndrome affects 0.5-1/100,000 live births.[ncbi.nlm.nih.gov] A woman with lupus nephritis presented 7 days postpartum with eclampsia. Postseizure findings included dramatic short-term memory loss.[ncbi.nlm.nih.gov] Hypertension plus other signs such as thrombocytopenia, elevated serum transaminase levels, or systemic organ failure is also sufficient for the diagnosis of preeclampsia[renalandurologynews.com]

  • Cladribine

    Hematologic toxicity was frequent: grade 3 anemia in 12%, grade 3 thrombocytopenia in 41%, grade 4 thrombocytopenia in 24%, grade 3 neutropenia in 6%, and grade 4 neutropenia[ncbi.nlm.nih.gov] Renal biopsy revealed WHO Class III lupus nephritis.[ard.bmj.com] We describe a 73-year-old woman who developed serious systemic vasculitis with associated thrombocytopenia in the course of treatment with cladribine.[ncbi.nlm.nih.gov]

  • Azathioprine

    Subgroups with leukopenia, anemia, thrombocytopenia, and liver dysfunction did not differ in concentrations of 6-TG or 6-MMP.[ncbi.nlm.nih.gov] To compare the efficacy of mycophenolate mofetil (MMF) with that of azathioprine (AZA) drugs in the maintenance therapy of lupus nephritis (LN) patients, we studied 81 Sudanese[ncbi.nlm.nih.gov] The resulting blood dyscrasias, leucopenia, thrombocytopenia or pancytopenia, can be life threatening.[medsafe.govt.nz]

  • Noonan Syndrome 1

    Thrombocytopenia and abnormal platelet function with abnormalities of coagulation factors are found in about 50% of cases resulting in easy bruising and prolonged bleeding[disorders.eyes.arizona.edu] […] most common and most severe form of lupus nephritis.[omicsonline.org] Due to coagulation factor deficiencies, platelet dysfunction, and/or thrombocytopenia, affected individuals may have a history of abnormal and easy bruising and bleeding.[rarediseases.org]

Further symptoms

Similar symptoms