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534 Possible Causes for Lupus Nephritis, Thrombocytopenia

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[] What is lupus nephritis? There are two types of lupus.[] Work-up suggested a diagnosis of active SLE with anaemia, thrombocytopenia, positive antinuclear antibodies (ANAs) and positive anti-double-stranded DNA.[]

  • Thrombotic Thrombocytopenic Purpura

    Careful analysis revealed the development of heparin-induced thrombocytopenia (HIT) that precluded platelet count (PLT) normalization.[] Autoimmune disease (lupus nephritis, acute scleroderma). Vasculitis. Haemolytic uraemic syndrome (diarrhoea positive/negative). Malignancy.[] Thrombotic thrombocytopenia purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by thrombocytopenia and microangiopathic hemolytic anemia[]

  • Nephrotic Syndrome

    We herein describe a case of nephrotic syndrome with thrombocytopenia, lymphadenopathy, systemic inflammation, splenomegaly, kidney enlargement, and progressive renal insufficiency[] Nephrotic syndrome (NS) is a major manifestation of lupus nephritis (LN).[] However, in thesetting of a nephrotic child who develops gross hematuria, thrombocytopenia, or unexplained persistent hypertension, renal ultrasound should be considered to[]

  • Chronic Myelomonocytic Leukemia

    thrombocytopenia").[] Most common causes include allergic reactions (eg, drug-induced), infections, auto-immune and infiltrative processes (eg, lupus nephritis and sarcoidosis), inflammatory disease[] Thrombocytopenia is usually the result of megakaryocytic dysplasia but the number of megakaryocytes may also be low contributing to thrombocytopenia.[]

  • Immunosuppressive Drug

    Review Topic QID: 101013 1 Nephrotoxicity, hypertension 3 Hyperlipidemia, thrombocytopenia 4 Cytokine release syndrome, hypersensitivity reaction 5 Nephrotoxicity, gingival[] lupus nephritis,” lead author Candace Feldman, MD, MPH, assistant professor of medicine, Harvard Medical School in Boston, and associate physician at Brigham and Women’s[] […] cumulative manifestations of SLE, in decreasing order of frequency, were musculoskeletal (70.3%), renal (52%), facial rash (46%), leukopenia (36%), photosensitivity (26%), thrombocytopenia[]

  • Cladribine

    Hematologic toxicity was frequent: grade 3 anemia in 12%, grade 3 thrombocytopenia in 41%, grade 4 thrombocytopenia in 24%, grade 3 neutropenia in 6%, and grade 4 neutropenia[] Renal biopsy revealed WHO Class III lupus nephritis.[] Adverse Reactions: Severe myelosuppression (eg, neutropenia, anemia, thrombocytopenia), fever, infection, fatigue, nausea, rash, headache, inj site reactions, others; neurotoxicity[]

  • Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[] The results suggest that lupus nephritis might be associated with physical activity.[] Yet, their roles in systemic lupus erythematosus (SLE) and lupus nephritis (LN) remain to be elucidated.[]

  • Azathioprine

    The resulting blood dyscrasias, leucopenia, thrombocytopenia or pancytopenia, can be life threatening.[] […] maintenance therapy in a Caucasian population suffering from proliferative lupus nephritis.[] Decreased red blood cell count (anemia) Other Serious Side Effects Liver toxicity Decreased platelet count (thrombocytopenia) Increased risk of infections Cancer Drug Interactions[]

  • Noonan Syndrome 1

    Thrombocytopenia and abnormal platelet function with abnormalities of coagulation factors are found in about 50% of cases resulting in easy bruising and prolonged bleeding[] […] most common and most severe form of lupus nephritis.[] Due to coagulation factor deficiencies, platelet dysfunction, and/or thrombocytopenia, affected individuals may have a history of abnormal and easy bruising and bleeding.[]

  • Tacrolimus

    Both patients (cases 1 and 2) developed fever, anasarca, thrombocytopenia, renal dysfunction, and mild hepatosplenomegaly.[] To further explore this, Mok and colleagues enrolled 150 patients between 2005 and 2012, all of whom had active lupus nephritis.[] Hematologic: anemia, leukocytosis, THROMBOCYTOPENIA. Musculoskeletal: back pain. Respiratory: pleural effusion, atelectasis, dyspnea. Skin: pruritus, rash.[]

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