Luteinizing Hormone Low, Obesity & Primary Amenorrhea: Causes & Reasons

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Possible Causes for Luteinizing Hormone Low, Obesity & Primary Amenorrhea

Kallmann Syndrome

These females, aged at 20 and 29-year-old, presented primary amenorrhea with prepubertal estradiol and low gonadotropin levels. [ncbi.nlm.nih.gov]

Serum luteinizing hormone levels were low or normal. [popline.org]

Patients with this genetic form of KS have been reported to have a possible increased prevalence of obesity and sleep disorders, which may be related to the role of PROK2 [ncbi.nlm.nih.gov]

Hypogonadotropic Hypogonadism Type 22

Normal MRI indicates a hypothalamic cause of amenorrhea. 3 Differential Diagnosis of Primary Amenorrhea Causes of primary amenorrhea should be evaluated in the context of [aafp.org]

His laboratory investigations showed low luteinizing hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. [atmph.org]

The hypogonadal-obesity cycle: Role of aromatase in modulating the testosterone-estradiol shunt - A major factor in the genesis of morbid obesity. [ijem.in]

Polycystic Ovary Syndrome

The females presented with primary amenorrhea. Both had partial alopecia especially on the temporo-parietal regions of the cranium. [jpma.org.pk]

hormone, follicle-stimulating hormone, total cholesterol, low-density lipoprotein C or insulin. [ncbi.nlm.nih.gov]

Insulin resistance in PCOS is unique and independent of obesity, as even non-obese women with this condition are frequently insulin resistant. [ncbi.nlm.nih.gov]

Turner Syndrome

A high thyroid stimulating hormone (TSH) result suggests the primary amenorrhea is due to primary hypothyroidism and should be followed with fT4 analysis. [clinicaladvisor.com]

The hormonal profile is characteristic, by reason of ovarian insufficiency, bringing about low levels of estrogen and high levels of follicle-stimulating hormone (FSH) and [scielo.br]

Life expectancy is slightly shorter than average but may be improved by attention to associated health issues - eg, obesity and hypertension. [patient.info]

Craniopharyngioma

[…] or secondary amenorrhea, often associated with galactorrhea. [dx.doi.org]

Reduction of sex hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). [pietromortini.com]

[…] vs control subjects with 'common' obesity. [ncbi.nlm.nih.gov]

Hypogonadotropic Hypogonadism

She is a 20-year-old tall, eunuchoid female referred for evaluation of primary amenorrhea. Spontaneous thelarche occurred at the age of 15 years. [ncbi.nlm.nih.gov]

Hormonal evaluation showed very low levels of gonadotropins, luteinizing hormone-releasing hormone test (LHRH test) and sexual steroids in both patients, suggesting a possible [ncbi.nlm.nih.gov]

Obesity has recently become one of the most important public health problems. [ncbi.nlm.nih.gov]

Luteinizing Hormone Deficiency

HH24 is characterized by primary amenorrhea in women, oligo or azoospermia with low to normal testosterone levels in men, and infertility. [genecards.org]

Low luteinizing hormone/follicle-stimulating hormone and estradiol levels suggest a hypothalamic problem. [healthhype.com]

Seite 160 - Obesity evaluation and treatment: Expert Committee recommendations. [books.google.de]

Kallmann Syndrome Type 3

Normal MRI indicates a hypothalamic cause of amenorrhea. 3 Differential Diagnosis of Primary Amenorrhea Causes of primary amenorrhea should be evaluated in the context of [aafp.org]

RESULTS: All patients were confirmed biochemically to have low luteinizing hormone (LH) and follicular stimulating hormone (FSH), and correspondingly low total testosterone [ncbi.nlm.nih.gov]

J Clin Endocrinol Metab. 2011;96(9):2643-51 Paresh Dandona and Sandeep Dhindsa wrote this update on hypogonadotropic hypogonadism (HH) in type 2 diabetes and obesity. [endocrineweb.com]

Hypogonadotropic Hypogonadism Type 18

Normal MRI indicates a hypothalamic cause of amenorrhea. 3 Differential Diagnosis of Primary Amenorrhea Causes of primary amenorrhea should be evaluated in the context of [aafp.org]

Isolated gonadotropin-releasing hormone (GnRH) deficiency (IGD) is characterized by inappropriately low serum concentrations of the gonadotropins LH (luteinizing hormone) [ncbi.nlm.nih.gov]

Hypogonadal Men: A Prospective Randomized Comparator Controlled Parallel Arm Clinical Trial Medical condition: Obesity Related Male Hypogonadism Disease: Version SOC Term [clinicaltrialsregister.eu]

Hypogonadism

PRIMARY AMENORRHEA SECONDARY AMENORRHEA. [nanopdf.com]

hormone (≤9.4 mU/mL)], secondary (low total testosterone, low/normal luteinizing hormone), primary (low total testosterone, elevated luteinizing hormone) and compensated [ncbi.nlm.nih.gov]

Furthermore, obesity is a risk factor for hypogonadism and conversely hypogonadism may be a risk factor for obesity. [ncbi.nlm.nih.gov]

Pituitary Neoplasm

hormone (LH) and/or follicle-stimulating hormone (FSH). [cancer.org]

Features of Cushing's disease, such as central obesity, moon facies, hypertension and development of a "buffalo hump", may be seen in ACTH-secreting tumors. [symptoma.com]

Hormonal deficiencies - Clinical effects Growth hormone deficiency Adults - Increased rate of cardiovascular disease, obesity, reduced muscle strength and exercise capacity [emedicine.medscape.com]

Primary Amenorrhea

CONCLUSIONS: The present study has currently been the largest case series of primary amenorrhea. [ncbi.nlm.nih.gov]

On investigation, she had microcytic hypochromic anemia, and her follicle-stimulating hormone and luteinizing hormone levels were low, while the thyroid-stimulating hormone [ncbi.nlm.nih.gov]

Chapters cover disorders in the major areas of endocrinology—hypothalamic-pituitary, thyroid, adrenal, metabolic bone, reproductive, diabetes, lipid disorders, obesity and [books.google.com]

Acquired Premature Ovarian Failure

A high thyroid stimulating hormone (TSH) result suggests the amenorrhea is due to primary hypothyroidism and should be followed with fT4 analysis. [clinicaladvisor.com]

She had high levels of FSH (follicle-stimulating hormone) and LH (luteinizing hormone) and low estrogen and progestin levels. [ispub.com]

 p/c: fatigue, amenorrhoea, infertility, male pattern baldness, acne, hirsuitism, anosmia (in Kallman’s syndrome), signs of oestrogen withdrawel (menopausal symptoms), obesity [mymedicalstudentnotes.com]

Isolated Follicle Stimulating Hormone Deficiency

Abstract Primary amenorrhea was observed in a 40-year-old woman with a proportionate female habitus. [ncbi.nlm.nih.gov]

Low luteinizing hormone/follicle-stimulating hormone and estradiol levels suggest a hypothalamic problem. [healthhype.com]

[…] neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity [books.google.de]

Acromegaly

Endocrinological examination revealed a high growth hormone (GH) concentration, low testosterone concentration, and high follicle-stimulating hormone and luteinizing hormone [ncbi.nlm.nih.gov]

High AG/UAG ratios are linked with type 2 diabetes, obesity, and hyperphagia (e.g., in Prader-Willi syndrome). [ncbi.nlm.nih.gov]

Most of the acromegaly-related comorbidities identified here are known to increase with age and obesity. [ncbi.nlm.nih.gov]

Kallmann Syndrome Type 2

Adult females have little or no breast development and primary amenorrhea. [ggc.org]

(FSH) and luteinizing hormone (LH) levels are low and there is no evidence of sexual maturation, to partial deficiency, in which FSH secretion predominates, allowing a certain [ommbid.mhmedical.com]

להמשך קריאה FDA Approves New Obesity Medication. [ies.org.il]

Secondary Amenorrhea

There are two types of amenorrhea: primary amenorrhea and secondary amenorrhea. Primary amenorrhea is the absence of a first period in a young woman by the age of 16. [my.clevelandclinic.org]

Here, we report a case of secondary amenorrhea with low serum luteinizing hormone and follicle-stimulating hormone levels due to an inhibin A- and inhibin B-producing granulosa [ncbi.nlm.nih.gov]

Abstract A massively obese, amenorrheic young woman had elevated levels of plasma androgens which could be reduced either acutely by dexamethasone administration or chronically [ncbi.nlm.nih.gov]

Autosomal Recessive Kallmann Syndrome Type 3

By contrast, our second patient consulted a doctor at 18 years of age, but the etiology of primary amenorrhea was not investigated at the time, and was simply treated as a [elsevier.es]

KS3 may be associated with spine curvature disorders, excessive joint mobility, flat feet, synkinesia, obesity, and sleeping disorders. [symptoma.com]

Hypogonadotropic Hypogonadism Type 8

Normal MRI indicates a hypothalamic cause of amenorrhea. 3 Differential Diagnosis of Primary Amenorrhea Causes of primary amenorrhea should be evaluated in the context of [aafp.org]

Online Letters: Observations Subnormal testosterone concentrations have been found in 25% of men with type 2 diabetes in association with inappropriately low luteinizing hormone [care.diabetesjournals.org]

Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity. [ajandrology.com]

Kallmann Syndrome Type 4

Amenorrhea Definition The absence of menstrual periods is called amenorrhea. Primary amenorrhea is the failure to start having a period by the age of 16. [medical-dictionary.thefreedictionary.com]

Clinically, this disorder is characterized by abnormally low plasma levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in conjunction with low or undetectable [synapse.koreamed.org]

J Clin Endocrinol Metab. 2011;96(9):2643-51 Paresh Dandona and Sandeep Dhindsa wrote this update on hypogonadotropic hypogonadism (HH) in type 2 diabetes and obesity. [endocrineweb.com]

Ovarian Dysgenesis

We present a case of a 33-year-old woman with Turner syndrome, primary amenorrhea and menopausal hormonal profile in which peritoneal endometriosis (white opacification type [ncbi.nlm.nih.gov]

Endocrine evaluation revealed elevated levels of follicle-stimulating hormone (77 IU/L) and luteinizing hormone LH (37 IU/L) with low estradiol ( Figure 1: Arrows show the [jhrsonline.org]

[…] disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. [books.google.com]

Leydig Cell Hypoplasia due to LHB Deficiency

amenorrhea or oligomenorrhea (absent or reduced menstruation ), infertility due to anovulation, and ovarian cysts. [2] [4] A related condition is follicle-stimulating hormone [en.wikipedia.org]

Type 1 is a severe form characterized by complete 46,XY male pseudohermaphroditism, low testosterone and high luteinizing hormone levels, total lack of responsiveness to luteinizing [mybiosource.com]

OBESITY In men with mild to moderate obesity, SHBG levels decrease in proportion to the degree of obesity, resulting in lower total testosterone levels. [clinicalgate.com]

Woodhouse-Sakati Syndrome

Case report; In a 52-year-old woman from a consanguine pedigree we observed mental retardation, short stature, alopecia with absence of eyebrows, hypogonadism, primary amenorrhea [bib.irb.hr]

Laboratory investigations revealed a low estradiol level (13 pg/mL; normal range: 21–251 pg/mL), normal luteinizing hormone level (8.09 mIU/L, normal range 1.8–11.78 mIU/L [e-jmd.org]

"[Clinical features, hormonal profile, and metabolic abnormalities of obese women with obese polycystic ovary syndrome]". [maria-online.com]

Anorchia

[…] and 5/31 of the cases of primary amenorrhea due to 46,XY DSD. [ncbi.nlm.nih.gov]

Tests include testosterone levels (low); follicle stimulating hormone and luteinizing hormone levels (elevated); X,Y karyotype; ultrasound or magnetic resonance imaging showing [bionity.com]

[…] disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. [books.google.com]

Female Infertility due to Anovulation

Patients with pure gonadal dysgenesis/agenesis are often short in stature with primary or secondary amenorrhea. [clinicaladvisor.com]

A simple means of distinguishing between the 2 conditions is to measure serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels (elevated in POF and low [www1.cgmh.org.tw]

Offers expanded coverage of genetics, diabetes and obesity-topics of increasing concern in pediatric endocrinology today. [books.google.com]

Panhypopituitarism

amenorrhea (delayed puberty), secondary amenorrhea, irregular menstrual cycles, infertility Males: delayed puberty, loss of libido, infertility, testicular atrophy, loss [amboss.com]

Luteinizing hormone and follicle-stimulating hormone levels were low to low-normal in 3 of the 4 patients. [ncbi.nlm.nih.gov]

Our patient had a GH deficiency, among others, in the context of hypopituitarism with abdominal obesity. [hindawi.com]

Hypopituitarism

She had a history of short stature treated with growth hormone (GH) in childhood and had hypothyroidism and primary amenorrhea at 20 years old. [ncbi.nlm.nih.gov]

Furthermore, insulin-like growth factor I was very low; follicle-stimulating hormone was normal; luteinizing hormone was low; total testosterone was very low, in the 30 ng [healio.com]

Gastric bypass surgery has been reported to be an efficient treatment strategy for morbid hypothalamic obesity. [ncbi.nlm.nih.gov]

Anterior Pituitary Hypofunction

[…] growth hormone deficiency, FSH, follicle-stimulating hormone, LH, luteinizing hormone, adrenocorticotropin hormone, ACTH, prolactin, ADH, antidiuretic hormone, low hormones [webmd.com]

[…] syndrome Diencephalic syndrome Diencephalic syndrome of infancy Diencephalic syndrome secondary to tumor Disorder of posterior pituitary Empty sella syndrome Endogenous obesity [icdlist.com]

Gonadotropin deficiency: FSH (follicular stimulating hormone) and LH (luteinizing hormone) are responsible for initiating and maintaining puberty. [chw.org]

Prolactinoma

Treatment with a dopamine agonist can be considered as the primary treatment with almost all microadenomas, including patients desiring pregnancy or those with primary amenorrhea [ncbi.nlm.nih.gov]

Laboratory testing showed an elevated prolactin of more than 17,000 ng/mL (normal, 0-15) and low luteinizing hormone 1 IU/L (normal, 1-9), follicle-stimulating hormone 1 IU [healio.com]

This 33-year-old woman was admitted to the internal medicine outpatient clinic for irregular menses, obesity, hirsutism and infertility, and hyperprolactinemia. [ncbi.nlm.nih.gov]

Ovarian Dysgenesis, Hypergonadotropic, X-Linked

The present study revealed a rare de novo sex autosome translocation in a female with primary amenorrhea. [thefreelibrary.com]

[…] disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. [books.google.com]