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15 Possible Causes for Luteinizing Hormone Low, Precocious Puberty in Males, Testicular Biopsy Abnormal

  • Klinefelter Syndrome

    puberty Increased risk of breast cancer — 20 times higher than that of the normal male population Dental Taurodontism (enlarged tooth size with reduced root size) and early[web.archive.org] Endocrinological examination revealed a high growth hormone (GH) concentration, low testosterone concentration, and high follicle-stimulating hormone and luteinizing hormone[ncbi.nlm.nih.gov] Testicular biopsies of KS infants and boys demonstrated decreased or absent germ cells and abnormal seminiferous tubules ( 16, 50 – 52 ).[dx.doi.org]

  • Central Precocious Puberty

    puberty in males.[ncbi.nlm.nih.gov] Although basal levels of luteinizing hormone and follicle-stimulating hormone are low, similar to what is expected in the pre-pubertal period, testosterone levels are high[ncbi.nlm.nih.gov] A testicular biopsy was not done. Our patient was treated with four cycles of preoperative chemotherapy (cisplatin, alternating with carboplatin/dox-orubicin).[cyberleninka.org]

  • Leydig Cell Tumor

    precocious puberty, and McCune–Albright syndrome (due to an activating mutation of arginine at position 201 in the α subunit of G s ). 22-24 In boys with male-limited precocious[nejm.org] Serum levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were inappropriately low for a post-menopausal woman, with high levels of estradiol.[scielo.br] Peripheral precocious puberty in a male caused by Leydig cell adenoma harboring a somatic mutation of the LHR gene: report of a case.[frontiersin.org]

  • Leydig Cell Hypoplasia

    precocious puberty (FMPP) [MIM:176410] 48,688,064(-) CACCG(A/G)TTTCA intron-variant, reference, missense rs121912519 Pathogenic, Familial male precocious puberty (FMPP) [[genecards.org] At first presentation, serum luteinizing hormone was about 3-fold above the normal limit, while testosterone was in the normal female adult range.[thieme-connect.com] By providing key information on the state of the testicular parenchyma and the potential reversibility of certain abnormalities, testicular biopsy can be of significant value[propath.com]

  • Hypogonadism

    -Prepubertal girls: analogous to males, but at lower levels, increased levels of testosterone are seen in precocious puberty.[mayomedicallaboratories.com] hormone ( 9.4 mU/mL)], secondary (low total testosterone, low/normal luteinizing hormone), primary (low total testosterone, elevated luteinizing hormone) and compensated[ncbi.nlm.nih.gov] If tests confirm that you have low testosterone, further testing can determine if a testicular disorder or a pituitary abnormality is the cause.[mayoclinic.org]

  • Anorchia

    puberty ).[britannica.com] Tests include testosterone levels (low); follicle stimulating hormone and luteinizing hormone levels (elevated); X,Y karyotype; ultrasound or magnetic resonance imaging showing[bionity.com] Testicular biopsy is rarely indicated (special fixative required).[rcpa.edu.au]

  • Male Pseudohermaphroditism

    In a dominant autosomal familial form of precocious puberty in boys (familial male-limited precocious puberty) LH receptor gene mutations have been identified.[doi.org] The diagnosis is made biochemically by the presence of low testosterone and estradiol values with elevated luteinizing hormone levels in the absence of other significant hormonal[ncbi.nlm.nih.gov] However, in these male assigned patients, consideration must be given to the role of periodic testicular biopsies.[auajournals.org]

  • Oligospermia

    Precocious puberty may indicate adrenogenital syndrome.[gfmer.ch] Identical twin brothers presented with oligospermia, small testes, normal male phenotypes, elevated serum luteinizing hormone levels, and normal or elevated serum testosterone[ncbi.nlm.nih.gov] Diagnosis : clinical examination, semen collection and analysis /- reproductive ultrasonography of the stallion, testicular biopsy if indicated.[vetstream.com]

  • Hypocupremia

    Male central precocious puberty: serum profile of anti-Müllerian hormone and inhibin B before, during, and after treatment with GnRH analogue. Int. J.[nature.com] Etiology of hypogonadism For men with confirmed low testosterone levels, serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels should be measured to[ncbi.nlm.nih.gov] If tests confirm that you have low testosterone, further testing can determine if a testicular disorder or a pituitary abnormality is the cause.[mayoclinic.org]

  • XXXXY Syndrome

    puberty.[patient.info] They also have increased serum follicle-stimulating hormone and luteinizing hormone concentrations.[britannica.com] A testicular biopsy specimen showed defective germ cell and tubule development.[karger.com]