Lymphadenopathy: Causes & Reasons

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Possible Causes for Lymphadenopathy

Infectious Mononucleosis

A 20-year-old man was hospitalized for the evaluation of lymphadenopathy and systemic symptoms. [ncbi.nlm.nih.gov]

Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy [ncbi.nlm.nih.gov]

Typical manifestations include fatigue (sometimes persisting weeks or months), fever, pharyngitis, splenomegaly, and lymphadenopathy. [merck.com]

Toxoplasmosis

[…] the case for seven of 16 patients with lymphadenopathy of less than 3 months’ duration. [cvi.asm.org]

After having obtained an insufficient evidence from the fine-needle biopsy, the patient finally received an excisional biopsy which highly indicated the possibility of lymphadenopathy [ncbi.nlm.nih.gov]

A 63-year-old woman presented with laterocervical and axillary bilateral lymphadenopathy. [ncbi.nlm.nih.gov]

Chronic Lymphocytic Leukemia

Lymphadenopathy may or may not be present. Stage III: Absolute lymphocytosis with anemia is present. Hepatosplenomegaly and lymphadenopathy may or may not be present. [symptoma.com]

After 3 years, he presented a CLL progression with worsening lymphocytosis, anemia, thrombocytopenia, increased splenomegaly, and lymphadenopathies. [ncbi.nlm.nih.gov]

III Lymphocytosis; lymphadenopathy; hepatosplenomegaly, anemia IV Lymphocytosis, lymphadenopathy; hepatosplenomegaly, thrombocytopenia ± anemia CHRONIC LYMPHOCYTIC LEUKEMIA [medical-dictionary.thefreedictionary.com]

Dermatopathic Lymphadenopathy

node hyperplasia and cutaneous disease was first described by Wise et al. although it was later established by Pantrier and Woringer as lipomelanotic reticulosis. [6], [7 [jcytol.org]

Abstract Documenting focal mycosis fungoides in lymph node biopsies that exhibit dermatopathic lymphadenopathy is morphologically difficult. [ncbi.nlm.nih.gov]

Systemic symptoms such as fever were recorded in 68% and multicentric lymphadenopathy was noted in 83% of patients. [ncbi.nlm.nih.gov]

Angioimmunoblastic Lymphadenopathy

Angioimmunoblastic lymphadenopathy with dysproteinemia is a disorder characterized by an acute onset of generalized lymphadenopathy associated with fever, malaise, pruritus [ncbi.nlm.nih.gov]

A patient with angioimmunoblastic lymphadenopathy with dysproteinemia had a monoclonal IgG hypergammaglobulinemia. [ncbi.nlm.nih.gov]

A 20-year-old man with ulcerative colitis was admitted because of fever, eruption and lymphadenopathy. He had started taking salazosulfapyridine one month previously. [ncbi.nlm.nih.gov]

Castleman Disease

Castleman disease also is referred to as: Castleman's disease Angiofollicular lymph node hyperplasia Giant lymph node hyperplasia CONTINUE SCROLLING OR CLICK HERE FOR RELATED [medicinenet.com]

The remaining 6 referral cases showed morphologic features consistent with reactive lymphadenopathy. [ncbi.nlm.nih.gov]

Castleman disease, also known as angiofollicular lymph node hyperplasia or giant lymph node hyperplasia, is an uncommon benign B-cell lymphoproliferative condition. [radiopaedia.org]

Adult-Onset Still Disease

Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis. [symptoma.com]

Essential features Fever, skin rash, joint pains, lymphadenopathy with paracortical hyperplasia and immunoblastic reaction Epidemiology Rare, shows female predilection and [pathologyoutlines.com]

CT scan showed enlarged cervical and mediastinal lymphadenopathy. [oatext.com]

Systemic Juvenile Idiopathic Arthritis

Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy. [symptoma.com]

Lymphadenopathy, splenomegaly, hepatomegaly, and sore throat are also common. [slideshare.net]

It is distinguished from other forms of JIA by extra-articular symptoms such as fever, hepatosplenomegaly, lymphadenopathy and serositis. [symptoma.com]

T-Cell Lymphoblastic Lymphoma

This was followed by the second episode of spontaneous tumor lysis syndrome and spontaneous regression of lymphadenopathy again. [ncbi.nlm.nih.gov]

T-cell lymphoblastic lymphoma with generalized lymphadenopathy and bone marrow involvement. [nepjol.info]

Two months after treatment, the patient showed near complete remission of the lymphadenopathy. [ncbi.nlm.nih.gov]

Waldenstrom Macroglobulinemia

The patient had no peripheral lymphadenopathy. On extensive investigation she was found to have pancreatic mass. [ncbi.nlm.nih.gov]

In contrast to myeloma, Waldenstrom cells can infiltrate into lymphoid organs, yielding lymphadenopathy and splenomegaly in some patients. [pathwaymedicine.org]

The presence of progressive, symptomatic lymphadenopathy or splenomegaly provide additional reasons to begin therapy. The presence of anemia with a hemoglobin value of [ncbi.nlm.nih.gov]

Follicular Lymphoma

The patient did not have any significant peripheral or axial lymphadenopathy, which made the diagnosis difficult in absence of histopathology. [ncbi.nlm.nih.gov]

This patient was a 58 years old with generalized lymphadenopathy and Ann Arbor Stage III disease. [ncbi.nlm.nih.gov]

In our report, a 62-year-old female was initially diagnosed with a low-grade follicular lymphoma, and 2 years later she presented with bilateral lung masses and lymphadenopathy [ncbi.nlm.nih.gov]

Multicentric Castleman's Disease

In this study, we examined clinical and pathologic findings of nine patients with systemic IgG4-related lymphadenopathy. [ncbi.nlm.nih.gov]

Axillary lymphadenopathy (large armpit lymph nodes) Cervical lymphadenopathy Cervical lymphadenopathy (large neck lymph nodes) Diffuse lymphadenopathy Diffuse lymphadenopathy [icd9data.com]

These findings were different from those of IgG4-related lymphadenopathy. [ncbi.nlm.nih.gov]

Sézary Syndrome

Sézary syndrome is a primary cutaneous T-cell lymphoma characterized by the triad of erythroderma, lymphadenopathy and circulating atypical cells. [ncbi.nlm.nih.gov]

Abstract Sézary syndrome is a primary cutaneous T-cell lymphoma characterized by pruritic erythroderma, peripheral lymphadenopathy and the presence of malignant T cells in [ncbi.nlm.nih.gov]

Definition / general Sézary syndrome (SS) is defined by the triad of erythroderma, generalized lymphadenopathy and the presence of clonally related neoplastic T cells with [pathologyoutlines.com]

Hodgkin Lymphoma

Although all the radiological examinations suggested an osseous anomaly, histopathologic evaluation of the pelvic lymphadenopathies provided definite diagnosis of the disease [ncbi.nlm.nih.gov]

Location of Lymphadenopathy More than 80% of patients with Hodgkin lymphoma present with lymphadenopathy above the diaphragm, often involving the anterior mediastinum; the [cancernetwork.com]

We report a case of an 18-year-old man, who presented with fever and was found to have pallor, generalised lymphadenopathy, hepatosplenomegaly, ascites and pedal oedema. [ncbi.nlm.nih.gov]

CINCA Syndrome

These attacks were accompanied with a low grade fever and an almost persistent skin rash and generalized lymphadenopathy. [cags.org.ae]

Nevertheless, many other manifestations are described, including fever, generalized lymphadenopathy, hepatosplenomegaly, developmental retardation, hydrocephalus, cerebral [digital.csic.es]

In addition, affected patients often show other features, including fever, lymphadenopathy, hepatosplenomegaly, progressive hearing loss, eye involvement (conjunctivitis, [cags.org.ae]

Anaplastic Large-Cell Lymphoma

Abstract Cervical lymphadenopathy in adults has a broad differential diagnosis, including bacterial and viral infections, Kikuchi-Fujimoto disease, systemic lupus erythematosus [ncbi.nlm.nih.gov]

However, due to the positive results for ALK and multiple lymphadenopathy, we diagnosed ALK-positive ALCL forming a solitary skin tumor on the forearm. [ncbi.nlm.nih.gov]

Our case presented with large pyogenic granuloma like lesion with regional lymphadenopathy. [idoj.in]

Cutaneous T-Cell Lymphoma

Subsequently, systemic spread occurs, including lymphadenopathy and hepatosplenomegaly. [amboss.com]

Clinical Information A form of cutaneous t-cell lymphoma manifested by generalized exfoliative erythroderma; pruritus; peripheral lymphadenopathy, and abnormal hyperchromatic [icd9data.com]

The patient turned chronically subfebrile 4 months before admission, and generalized peripheral lymphadenopathy occured. [cyberleninka.org]

Diffuse Large B-Cell Lymphoma

A 70-year-old woman with lymphadenopathy was admitted to hospital in 2008. [ncbi.nlm.nih.gov]

In July 2008, he exhibited systemic multifocal lymphadenopathy and was diagnosed with DLBCL. [ncbi.nlm.nih.gov]

We are reporting a 9-year-old female child presented with diffuse lymphadenopathy postheart transplantation. [ncbi.nlm.nih.gov]

Hairy Cell Leukemia

Based on these findings, we diagnosed the patient with systemic lymphadenopathy due to HCL. [ncbi.nlm.nih.gov]

[…] which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy [icd9data.com]

Lymphadenopathy is usually not seen. [ncbi.nlm.nih.gov]

Cytomegalovirus Mononucleosis

CMV is thought to provoke larger mesenteric lymphadenopathy and swelling of the eyelids. [symptoma.com]

Cervical lymphadenopathy, hepatomegaly and lymphocytosis (greater than 5000/microliter) were more common in children and protracted fever more common in adults. [ncbi.nlm.nih.gov]

The patient was a young woman with fever that had persisted for 24 days, and with relative bradycardia, hepatosplenomegaly, suboccipital lymphadenopathy and a rash. [ncbi.nlm.nih.gov]

Cat Scratch Fever

Select Common Diseases That May Be Confused with Cat-scratch Disease Unilateral Lymphadenopathy Infectious causes Cytomegalovirus lymphadenopathy* Epstein-Barr virus lymphadenopathy [aafp.org]

Of these benign neoplasms, 20 were adenomas, 14 were cystic lesions, 14 were cases of lymph node hyperplasia, and 2 were neurinomas; in addition, there was 1 case each of [doi.org]

One to three weeks after the appearance of the primary lesion, regional lymphadenopathy appears, usually next to the inoculation site. [patient.info]

Whipple Disease

We describe 2 patients with Whipple disease whose initial manifestation was lymphadenopathy. [ncbi.nlm.nih.gov]

’s Disease Lymphadenopathy? [dovemed.com]

We describe a 63-year-old man in whom Whipple disease was diagnosed 22 years after his initial presentation (36 years after symptom onset) with lymphadenopathy, when a biopsy [ncbi.nlm.nih.gov]

Primary HIV Infection

In patients with persistent lymphadenopathy, serology tests for cytomegalovirus and Epstein-Barr virus should be performed. [symptoma.com]

A male homosexual presented with a skin rash, pharyngitis, fever and lymphadenopathy. The clinical symptoms were suggestive of an acute primary HIV infection. [ncbi.nlm.nih.gov]

Clinical findings Fever, severe fatigue, sore throat, lymphadenopathy, anorexia, nausea, vomiting, and a maculopapular rash; less commonly, diarrhoea, lightning-like pain, [medical-dictionary.thefreedictionary.com]

Congenital AIDS

However, in addition to AIDS as defined by the CDC, it is clear that there are several related syndromes which include individuals with chronic lymphadenopathy, fever, and [pediatrics.aappublications.org]

[…] non-Hodgkin's lymphoma (other than primary brain lymphoma), lymphocytic leukemia, multiple myeloma, any other cancer of lymphoreticular or histiocytic tissue, or angioimmunoblastic lymphadenopathy [books.google.com]

Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. [ebi.ac.uk]

Kaposi Sarcoma

The course of the disease was very aggressive; the patient died four weeks after general lymphadenopathy appearance. [ncbi.nlm.nih.gov]

(may be present in up to 50%) 5 lymphadenopathy is typically of high attenuation 6 On liver CT: ill-defined multifocal peripheral portal nodules with variable attenuation [radiopaedia.org]

node hyperplasia Plasmablastic form Sex – M:F, equal Usually presents during 30s-40s Most common in HIV-positive patients Other at risk groups include transplant patients [arupconsult.com]

Tularemia

To the best of our knowledge, these are the firstly described abdominal lymphadenopathy cases from Turkey. [ncbi.nlm.nih.gov]

Ultrasound may demonstrate suppurative lymphadenopathy suggestive of infection, as in the case presented. CT often will demonstrate the extent of lymphadenopathy. [ncbi.nlm.nih.gov]

Glandular tularemia should be considered in the differential diagnosis of inguinal lymphadenopathy. [ncbi.nlm.nih.gov]

Histoplasmosis

He developed numerous erythema nodosum leprosum-like mucocutanous lesions accompanied by fever, generalized lymphadenopathy, and weight loss. [ncbi.nlm.nih.gov]

Lesions may also be deep, with infiltrative edges and erythematous or with white areas, accompanied by local lymphadenopathy, resembling a carcinoma on clinical examination [ncbi.nlm.nih.gov]

Adrenal enlargement, oral ulcers and lymphadenopathy were common presentations in four patients each. [ncbi.nlm.nih.gov]

Rubella

The tenderness that accompanies this lymphadenopathy subsides rapidly, however the enlargement may last days or weeks. [atsu.edu]

He was admitted with a headache, fever, loss of consciousness and bilateral retroauricular lymphadenopathy. [ncbi.nlm.nih.gov]

Diagnosis The occurrence of the typical rash and lymphadenopathy may suggest the diagnosis of rubella. [ncbi.nlm.nih.gov]

Disseminated Histoplasmosis

Histoplasmosis was acquired in South America; its manifestations included prolonged fever, splinter hemorrhages, erythema multiforme, arthritis, and mediastinal lymphadenopathy [ncbi.nlm.nih.gov]

The patient in the present case report was immunocompetent child and had fever, bone pains, gradual weight loss, lymphadenopathy and hepatosplenomegaly. [ncbi.nlm.nih.gov]

Obstructive respiratory difficulty due to tracheobronchial lymphadenopathy also has been seen in dogs. [merckvetmanual.com]

Disseminated Infection with Mycobacterium Avium Complex

[…] dose of IFN-alpha2b (3 x 10(6) units/m(2) three times weekly subcutaneously) successfully attenuated progressive hepatosplenomegaly and abdominal/retroperitoneal/pelvic lymphadenopathy [ncbi.nlm.nih.gov]

During the physical examination, diffuse lymphadenopathy and hepatosplenomegaly may be noted. [symptoma.com]

Small pleural effusion and hilar lymphadenopathy are also noted. [ncbi.nlm.nih.gov]