Create issue ticket

1,995 Possible Causes for Lymphadenopathy, Splenomegaly

  • Infectious Mononucleosis

    To depict the grey-scale and Doppler features of cervical lymphadenopathy due to infectious mononucleosis (IM) and to compare the findings with other benign conditions and[ncbi.nlm.nih.gov] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov]

  • Upper Respiratory Infection

    Primary HIV infection can be another cause of lymphadenopathy.[emedicine.medscape.com] Her throat appeared to have erythematous, swollen tonsils, greater on the left with left-sided cervical lymphadenopathy and diffuse, painful swelling.[healio.com] Centor Criteria for Pharyngitis and Tonsillitis Clinical finding Points Absence of cough 1 Age 3 to 14 years 1 15 to 45 years 0 Older than 45 years –1 Anterior cervical lymphadenopathy[aafp.org]

  • Malignant Neoplasm

    To date, phenytoin-induced nasopharyngeal lymphadenopathy has not previously been reported in the literature.[ncbi.nlm.nih.gov] No hilar or mediastinal lymphadenopathies were found. Unilateral left upper lobectomy was performed and the sample was sent for pathology analysis.[archbronconeumol.org] A case of phenytoin sodium-induced lymphadenopathy appeared as a nasopharyngeal malignant neoplasm with regional metastases.[ncbi.nlm.nih.gov]

  • Pharyngitis

    Presence of hepatosplenomegaly or lymphadenopathy outside the cervical region should raise suspicions regarding an underlying malignancy.[ncbi.nlm.nih.gov] It is characterised by : Sore throat Fever Enlarged cervical lymph nodes Enlarged tonsils and fatigue Other clinical manifestations are splenomegaly (enlarged spleen), hepatomegaly[singhealth.com.sg] Splenomegaly and/or hepatomegaly can be present in more than 50% of patients.[infectiousdiseaseadvisor.com]

  • Castleman Disease

    Castleman disease, also known as angiofollicular lymph node hyperplasia and giant lymph node hyperplasia, represents a group of non-neoplastic lymphoproliferative disorders[symptoma.com] Older age ( 40 years), splenomegaly, and hypoalbuminemia were risk factors for poorer MCD prognosis.[ncbi.nlm.nih.gov] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis.[symptoma.com] […] clinically by high spiking fever, polyarthralgia/arthritis, a salmon-pink evanescent rash, predominantly neutrophilic leucocytosis, lymphadenopathy, liver dysfunction, and splenomegaly[ncbi.nlm.nih.gov] Arthritis (OR, 8.6; 95% confidence interval [CI], 1.5-49.1; p 0.014), pharyngitis (OR, 6.9; 95% CI, 1.5-30.2; p 0.010), splenomegaly (OR, 5.4; 95% CI, 1.1-26.7; p 0.039),[ncbi.nlm.nih.gov]

  • Follicular Lymphoma

    The patient did not have any significant peripheral or axial lymphadenopathy, which made the diagnosis difficult in absence of histopathology.[ncbi.nlm.nih.gov] Splenic infiltration of lymphoma cells may cause splenomegaly in many cases.[ncbi.nlm.nih.gov] This patient was a 58 years old with generalized lymphadenopathy and Ann Arbor Stage III disease.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Abdominal examination reveals splenomegaly, palpable 8 cm. below the costal margin without hepatomegaly CT scans of the chest, abdomen, and pelvis reveal moderate mediastinal lymphadenopathy[targetedonc.com]

  • Hairy Cell Leukemia

    Based on these findings, we diagnosed the patient with systemic lymphadenopathy due to HCL.[ncbi.nlm.nih.gov] Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov] Lymphadenopathy is usually not seen.[ncbi.nlm.nih.gov]

  • T-Cell Lymphoma

    Hepatosplenomegaly and systemic lymphadenopathy were detected by enhanced computed tomography.[ncbi.nlm.nih.gov] Splenomegaly and adenopathy in mesentery, retro peritoneum and lymph node chains in the limbs were observed.[ncbi.nlm.nih.gov] A man in his 30s presented to our hospital with fever, hypereosinophilia, widespread lymphadenopathy, and splenomegaly.[ncbi.nlm.nih.gov]

Further symptoms

Similar symptoms