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1,115 Possible Causes for Lymphocyte Disorder, Splenomegaly

  • Non-Hodgkin Lymphoma

    ) Acute Lymphoblastic Leukemia (ALL) Acute Myeloid Leukemia (AML) Amyloidosis Bleeding & Clotting Disorders Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia[healthcare.utah.edu] Computed tomography scan of the chest and abdomen showed paratracheal and subcarinal lymphadenopathy and splenomegaly, with the findings being compatible with lymphoma.[ncbi.nlm.nih.gov] Splenomegaly. Hepatomegaly. Intermediate- and high-grade lymphomas: Most patients present with rapidly growing and bulky lymphadenopathy.[patient.info]

  • Chronic Lymphocytic Leukemia

    LPDs), including chronic lymphocytic leukemia (CLL).[ncbi.nlm.nih.gov] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov] Chronic lymphocytic leukemia (CLL) is a B cell lymphoproliferative disorder that characteristically presents in older individuals.[ncbi.nlm.nih.gov]

  • Castleman Disease

    […] body’s excess production of B lymphocytes, resulting in swollen or tumorous lymph nodes, glands, or organs.[disability-benefits-help.org] Older age ( 40 years), splenomegaly, and hypoalbuminemia were risk factors for poorer MCD prognosis. 2017 The Authors.[ncbi.nlm.nih.gov] Facing a patient with fever, peripheral lymphadenopathy, splenomegaly, and the biochemical and immunological picture depicted above, the physician may find it difficult to[symptoma.com]

  • Hairy Cell Leukemia

    Hairy cell leukemia: a B-lymphocytic disorder derived from splenic marginal zone lymphocytes? Blut. 1985 ; 50 : 191 -194. Dierlamm J, Stefanova M, Wlodarska I, et al.[doi.org] Most patients are middle-aged to elderly adults and present with splenomegaly and pancytopenia.[icd9data.com] Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov]

  • Prolymphocytic Leukemia

    Prolymphocytic leukemia (PLL) is a rare lymphocytic disorder characterized by marked lymphocytosis and splenomegaly and represents only 2% of all mature lymphocytic leukemias[ncbi.nlm.nih.gov] However, the generalized lymphadenopathy and splenomegaly did not improve. The patient underwent splenectomy to palliate abdominal distension and hypersplenism.[ncbi.nlm.nih.gov] PubMed Google Scholar Bartlett NL, Longo DL: T-small lymphocyte disorders. Semin Hematol 1999, 36: 164–170.[ehoonline.biomedcentral.com]

  • Intestinal Lymphoma

    Lymphocyte depleted or not depleted Nodular lymphocyte-predominant Hodgkin lymphoma Immunodeficiency-associated lymphoproliferative disorders Associated with a primary immune[en.wikipedia.org] However, the presence of extensive retroperitoneal lymphadenopathy and splenomegaly favours lymphoma, whereas adjacent fat infiltration supports adenocarcinoma.[radiopaedia.org] Bulky mesenteric or retroperitoneal lymphadenopathy and splenomegaly are findings that support the diagnosis of a lymphoma.[radiologyassistant.nl]

  • Lymphoproliferative Disorder

    The B cell lymphocytic disorders include B-chronic lymphocytic leukaemia, B cell prolymphocytic leukaemia, chronic lymphocytic leukaemia-prolymphocytic leukaemia, non-Hodgkin's[ncbi.nlm.nih.gov] She was treated successfully with chemotherapy and radiation therapy but presented with lymphadenopathy and splenomegaly 74 months after transplantation.[ncbi.nlm.nih.gov] A 49-year-old Chinese man presented to our hospital with fever, enlargement of multiple superficial lymphonodes more than 14 years and splenomegaly.[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Paul AH Moss and Mark T Drayson, Normal Lymphocytes and Non‐Neoplastic Lymphocyte Disorders, Postgraduate Haematology, (343-367), (2010).[oadoi.org] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] […] inguinal or axillary adenopathy (specificity range, 0.82-0.91; positive LR range, 3.0-3.1), palatine petechiae (specificity, 0.95; positive LR, 5.3 [95% CI, 2.1-13]), and splenomegaly[doi.org]

  • Autoimmune Lymphoproliferative Syndrome

    Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte apoptosis.[ncbi.nlm.nih.gov] We conclude that in selected patients with marked splenomegaly and ALPS, splenectomy may be considered a treatment option.[ncbi.nlm.nih.gov] The occurrence of Fas mutations together with abnormal T cell apoptosis in ALPS patients suggests an involvement of Fas in this recently recognized disorder of lymphocyte[ncbi.nlm.nih.gov]

  • Persistent Polyclonal B-cell Lymphocytosis

    Suggestions for identifying the disorder are made.[ncbi.nlm.nih.gov] Abstract Five cases of persistent polyclonal B-cell lymphocytosis (PPBL) with progressive splenomegaly are reported; three were splenectomized.[ncbi.nlm.nih.gov] Significant symptomatic splenomegaly requiring splenectomy is very unusual for this disorder; therefore there is a lack of descriptions of the morphologic features of the[ncbi.nlm.nih.gov]

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