Cartilage hair hypoplasia is a rare multisystemic genetic disorder demarcated by a short stature from birth, hypoplastic hair, various skeletal abnormalities and a variable degree of immunodeficiency that can be fatal in the absence of an early diagnosis. Clinical signs, results from imaging studies, and genetic testing…
Chronic eosinophilic leukemia is a rare myeloid malignancy characterized by primary eosinophilia and progressive organ damage. Diagnosis of this disease and distinction from idiopathic hypereosinophilic syndrome requires the detection of determined mutations, demonstration of clonality of eosinophils, or observation of…
Pappataci fever (also known as Phlebotomus fever and, somewhat confusingly, sandfly fever and three-day fever) is a vector-borne febrile arboviral infection caused by three serotypes of Phlebovirus. It occurs in subtropical regions of the Eastern Hemisphere. The name, pappataci fever, comes from the Italian word…
Congenital acquired immune deficiency syndrome occurs due to mother-to-child transmission of HIV in utero, during delivery or breast-feeding. Depending on various factors, around 5-50% of children born to HIV+ mothers are infected. The diagnosis is made by a combination of clinical and immunological criteria, while…
The clinical presentation starts after 5-14 days from tick bite. The following system-wise presentation is seen in erlichiosis: General Appearance: Patients with erlichiosis may present with confusion in 20% of cases and malaise due to the rapid destruction of the white blood cells in the system. The general feeling…
Acquired immunodeficiency syndrome (AIDS) is considered to be the most severe stage of human immunodeficiency virus (HIV) infection. It is life-threatening if therapy is not initiated immediately. Patients present with constitutional symptoms of variable severity, wasting, and numerous AIDS-defining illnesses. Clinical…
Lymphocytopenia, but not idiopathic CD4+ lymphocytopenia, is associated with corticosteroid use, infections with HIV and other viral, bacterial, and fungal agents, malnutrition … In T lymphocytopenia, there are too few T lymphocytes, but normal numbers of other lymphocytes. … Lymphocytopenia, or lymphopenia, is the condition of having an abnormally low level of lymphocytes in the blood.
The results may be notable for anemia, lymphocytopenia, and elevated lactic dehydrogenase (LDH).