Lymphopenia Causes & Reasons

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Lymphopenia Symptom Checker: Possible causes include Tonsillitis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Lymphopenia,

Negated

None

Unsure

None

Possible Causes

Tonsillitis

Tonsillitis is an infectious disease characterized by inflammation of the tonsils in the throat region. It is caused either due to viral or bacterial infection. Children with tonsillitis have swollen tonsils that turn red accompanied by fever and inability to swallow food due to sore and painful throat. Affected individuals[…] [symptoma.com]

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COVID-19

In 63% of the patients, lymphopenia was observed. Abnormal findings on chest CTs were observed for all 41 patients. [contagionlive.com]

[…] non-specific: fever myalgia malaise non-productive cough pleuritic pain dyspnea Laboratory tests The most common findings in a study of 138 hospitalized patients were 13: lymphopenia [radiopaedia.org]

She was tachypneic (30bpm), with lymphopenia and low oxygen saturation (SpO2 85%). [radiologyassistant.nl]

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Childhood Hodgkin Lymphoma

The complete cell blood count may show neutrophilia or eosinophilia, lymphopenia or monocytosis, anemia or thrombocytopenia. [symptoma.com]

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Angioimmunoblastic Lymphadenopathy

It is characterized by acute onset, severe constitutional symptoms, cervical or generalized lymphadenopathy, lymphopenia, and polyclonal hypergammaglobulinemia, all of which [ncbi.nlm.nih.gov]

( eMedicine ) Laboratory Polyclonal hypergammaglobulinemia and autoimmune hemolytic anemia ( Hsi: Hematopathology, Second Edition, 2012 ) Eosinophilia, thrombocytopenia, lymphopenia [pathologyoutlines.com]

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Congenital AIDS

One of the early clues to an acquired immunodeficiency state is the development of absolute lymphopenia. [hemonc.mhmedical.com]

[…] secretion of tolerogenic cytokines Cytopenias Decreased cellular immunity and anergy Stress-induced nonspecific immune activation Infectious diseases: HIV infection T-cell lymphopenia [incodom.kr]

[…] recessive) IL-2RG(X-linked) Oral candidiasis, Pneumocystis jirovecii pneumonia, diarrhea before 6 months, failure to thrive, graft vs host disease, absent thymic shadow, lymphopenia [msdmanuals.com]

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Acquired Immunodeficiency Syndrome

Lymphopenia was not common, as it is in adult patients. [nejm.org]

He was hospitalized again in April with fever, splenomegaly, anemia, and lymphopenia. [cdc.gov]

Masur et al (2) also reported that lymphocyte dysfunction and lymphopenia were similar in heterosexual and homosexual cases of PCP. [cdc.gov]

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Intestinal Lymphangiectasia

The objective of this study was to better characterize the lymphopenia of PIL-confirmed patients. [ncbi.nlm.nih.gov]

[…] lymphangiectasia (Waldmann's disease) is an exudative enteropathy characterized by lymph leakage into the small bowel lumen leading to hypoalbuminemia, hypogammaglobulinemia and lymphopenia [ncbi.nlm.nih.gov]

[…] rare disorder characterized by dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen and responsible for protein-losing enteropathy leading to lymphopenia [ncbi.nlm.nih.gov]

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Ehrlichiosis

In this study, we compared the immune responses in two patients with mild/non fatal and severe/fatal HME who had marked lymphopenia, thrombocytopenia and elevated liver enzymes [ncbi.nlm.nih.gov]

Common laboratory abnormalities included thrombocytopenia (94%), elevated aspartate aminotransferase (90%), elevated alanine aminotransferase (74%), hypoalbuminemia (65%), lymphopenia [ncbi.nlm.nih.gov]

Clinical laboratory findings may include thrombocytopenia, lymphopenia, leucopenia, and elevated liver enzymes. [dhs.wisconsin.gov]

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Cartilage Hair Hypoplasia

Here, we present a case of CHH with mild skeletal changes and immunological findings associated with recurrent otitis media, neutropenia, and lymphopenia. [ncbi.nlm.nih.gov]

Sixty-two percent of the patients had had lymphopenia and 24% neutropenia. [ncbi.nlm.nih.gov]

Irrespective of clinical phenotype, most patients had lymphopenia and reduced lymphocyte proliferation to mitogens in vitro. [ncbi.nlm.nih.gov]

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Lymphopenia

lymphopenia in 10%. [doi.org]

There is surprisingly little literature on lymphopenia in SLE, despite its common occurrence in this disorder. 24, 25, 45, 46 Lymphopenia is well known to predispose to infections [doi.org]

Lymphopenia was an important risk factor for major infections in this group of Chinese patients in the early stages of SLE. [ncbi.nlm.nih.gov]

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Idiopathic CD4 Lymphocytopenia

It may be discovered that some of the patients diagnosed during infancy with idiopathic T-cell lymphopenia represent the earliest presentation of the idiopathic CD4-cell lymphopenia [frontiersin.org]

I would also consider an ANA since SLE may result in lymphopenia. [aaaai.org]

Causes of Lymphopenia Lymphopenia can be caused by many conditions, including infection and medication side effect. At times, the condition may only affect lymphocytes. [verywell.com]

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Chronic Eosinophilic Leukemia

As expected, all patients developed lymphopenia during treatment with alemtuzumab. [clincancerres.aacrjournals.org]

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Severe Combined Immunodeficiency

A full blood count revealed profound lymphopenia. The child was diagnosed with adenosine deaminase deficiency, a rare cause of severe combined immunodeficiency (SCID). [ncbi.nlm.nih.gov]

METHODS: Between May 1, 2010 and December 31, 2011, the National Taiwan University Hospital Newborn Screening Center screened all newborns for T-cell lymphopenia by measuring [ncbi.nlm.nih.gov]

Newborn screening (NBS) for severe combined immunodeficiency (SCID) is now identifying infants with 22q11.2DS due to T cell lymphopenia. [ncbi.nlm.nih.gov]

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Middle East Respiratory Syndrome

All 3 patients had fever, cough, shortness of breath, bilateral infiltrates on chest x-ray, thrombocytopenia, lymphopenia and rises in serum creatinine kinase and alanine [ncbi.nlm.nih.gov]

Laboratory analyses showed raised concentrations of lactate dehydrogenase (23 [49%]) and aspartate aminotransferase (seven [15%]) and thrombocytopenia (17 [36%]) and lymphopenia [ncbi.nlm.nih.gov]

Lymphopenia was the most common finding in a cohort of 157 patients with SARS. [doi.org]

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Primary Immune Deficiency Disorder

Laboratory investigation showed that our patient had WBC of 9500/uL, lymphopenia (ALC: 600 cells/uL) with low T cells (7 cells/uL), very low both CD4 (4 cells/uL) and CD8 [hindawi.com]

Here, the authors report homozygous FCHO1 mutations in individuals with variable T and B cell lymphopenia, which are associated with loss-of-function of FCHO1 and impaired [nature.com]

Features of SCID • Absent tonsils • Small or absent lymph nodes • Absent thymic shadow • Lymphopenias • Decreased Number of T cells • Severe agammaglobulinemia (Swiss type [slideshare.net]

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Phlebotomus Fever

Infected individuals developed a marked leukopenia characterized by an initial lymphopenia followed by protracted neutropenia. [ncbi.nlm.nih.gov]

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Laron Syndrome with Immunodeficiency

Immunodeficiency is characterized by moderate lymphopenia which leads to recurrent infections of the skin and respiratory tract. [orpha.net]

Standard analyses do not usually show any anomalies, but moderate lymphopenia and hypergammaglobulinemia have been reported. [symptoma.com]

In patients with STAT5B deficiency, moderate lymphopenia with lack of CD3 , CD4 , and CD8 T cells, CD4 /CD25 regulatory T cells, γδ T cells, and NK cells has been described [symptoma.com]

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Protein-Losing Enteropathy

The diagnosis of lupus was established based on the presence of lymphopenia, proteinuria, ANA, and positive autoantibodies (anti-Sm, anti-DNA, and anti-Ro). [ncbi.nlm.nih.gov]

It is characterized by dilation and leakage of intestinal lymph vessels leading to hypoalbuminemia, hypogammaglobulinemia and lymphopenia. [ncbi.nlm.nih.gov]

All patients with PLE had lymphopenia compared with 25% of controls (P .01). [ncbi.nlm.nih.gov]

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Adenosine Deaminase Deficiency

She had frequent infections, lymphopenia, and recurrent hepatitis as a child but did relatively well in her second and third decades. [ncbi.nlm.nih.gov]

The clinical effects of ADA deficiency are manifest most dramatically in the immune system, where it leads to severe lymphopenia. [ncbi.nlm.nih.gov]

A three-yr-old Japanese boy was diagnosed with delayed-onset ADA deficiency because of recurrent bronchitis, bronchiectasia, and lymphopenia. [ncbi.nlm.nih.gov]

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Leukopenia

OBJECTIVE: To systematically review the available evidence to evaluate (1) the prevalence and degree of leukopenia, lymphopenia, and neutropenia in patients with systemic [ncbi.nlm.nih.gov]

Lymphopenia and GC use are known risk factors for infections in SLE patients. [consultqd.clevelandclinic.org]

Learn about the different types of leukopenia: neutropenia and lymphopenia and their causes. Leukopenia Inside your bones, there are small but productive factories. [study.com]

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Disseminated Histoplasmosis

[…] protein - 40 mg/L (normal [7] based on malar rash, photosensitivity, nonerosive arthritis, positive ANA, serositis (pleural effusion), and hematological disorder (leukopenia, lymphopenia [e-ijd.org]

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Congenital Chylothorax

Lymphopenia lasted for 12 d median (range 4-39 d) and was significantly correlated with the duration of lymph drainage (p 0.001). [ncbi.nlm.nih.gov]

Congenital chylothorax: Lymphopenia and high risk of neonatal infections. Acta Paediatr 2004;93:220-4. 4. Dubin PJ, King IN, Gallagher PG. Congenital chylothorax. [jcnonweb.com]

All infants suffered from hypoalbuminaemia, electrolyte imbalances, clotting dysfunction, lymphopenia, anaemia and immune deficiency due to chronic loss of immunoglobulins [erj.ersjournals.com]

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Primary Intestinal Lymphangiectasia

The objective of this study was to better characterize the lymphopenia of PIL-confirmed patients. [ncbi.nlm.nih.gov]

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Good's Syndrome

A complete blood count (CBC) is mandatory and should be obtained right away, with anemia, leukopenia (either granulocytopenia or lymphopenia) and/or thrombocytopenia being [symptoma.com]

Evaluation of his immune status during the terminal illness revealed hypogammaglobulinemia and lymphopenia consistent with a diagnosis of Good's syndrome (immunodeficiency [ncbi.nlm.nih.gov]

Although the cryptococcus is a recognised fungal pathogen in patients with other causes of CD4 T cell lymphopenia, surprisingly this complication has not been reported in [ncbi.nlm.nih.gov]

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Activated PI3K-Delta Syndrome

Definition A disorder characterized by recurrent respiratory infections, progressive airway damage, lymphopenia, increased circulating transitional B cells, increased immunoglobulin [uniprot.org]

Immunologically, patients display lymphopenia, increased transitional B cells, elevated IgM, variable reductions in IgG, and T cell exhaustion. [lifesci.dundee.ac.uk]

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Purine-Nucleoside Phosphorylase Deficiency

Progressive lymphopenia, ataxia, and developmental delay led to diagnosis. Umbilical cord blood transplantation corrected the immunodeficiency. [ncbi.nlm.nih.gov]

There is severe lymphopenia with decreased absolute numbers of T and B lymphocytes. [ncbi.nlm.nih.gov]

Lymphopenia, reduced serum uric acid, and abnormal PNP enzymatic activity assist in the diagnosis of PNP-deficient patients. [ncbi.nlm.nih.gov]

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Immunodeficiency Type 23

Immunodeficiency Decreased immune function 0002721 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Lymphopenia [rarediseases.info.nih.gov]

We identified three unrelated children with recurrent infections, congenital leukopenia including neutropenia, B and T cell lymphopenia, and progression to bone marrow failure [f1000.com]

[…] received hematopoietic stem cell transplantation of cord blood and bone marrow from matched related donors; both had successful engraftment and correction of neutropenia and lymphopenia [f1000.com]

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Schimke Immunoosseous Dysplasia

We report on a 16-year-old girl with spondyloepiphyseal dysplasia, nephrotic syndrome, lymphopenia, and signs of defective cellular immunity. [ncbi.nlm.nih.gov]

He had recurrent lymphopenia with low CD4/CD8 ratio. However lymphopenia respond to granulocyte colony-stimulating factor (G-CSF), he died with pneumonia and sepsis. [ijp.mums.ac.ir]

Recurrent episodes of lymphopenia were documented. [docslide.com.br]

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Acute Sarcoidosis

IgG (approx. 50% of patients) Angiotensin-converting enzyme (ACE) blood levels; may be used to monitor disease activity and therapy Inflammatory markers, possible lymphopenia [amboss.com]

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Combined Immunodeficiency due to CD3-Gamma Deficiency

[…] context to support the T-cell lymphopenia. [aacc.org]

JAK3 deficiency: Lymphopenia occurs primarily from the absence or near absence of T cells (CD3 ) and NK cells. [odlarmed.com]

Immunological findings are lymphopenia with the absence of T and NK cells, hypogammaglobulinemia, and normal or increased B cell count. [orpha.net]

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