The average age of CLL patients is more than 70 years and it should be noted that a complex clinical picture occurs in more than half of the cases due to coexisting diseases. The CLL itself leads to unspecific symptoms such as general malaise and weakness, possibly also to fever, night sweats and weight loss. In…
Hairy cell leukemia (HLC) is a rare, chronic form of B-lymphocytic leukemia.
Patients usually present on diagnosis with pancytopenia, splenomegaly, and circulating hairy cells. All the signs and symptoms of hairy cell leukemia are the result of the proliferation of the abnormal white blood cells. All of the symptoms are…
Acute lymphocytic leukemia (ALL), otherwise referred to as acute lymphoblastic leukemia or acute lymphoid leukemia, is a hematopoietic malignancy that involves the overproduction of cancerous white blood cells in the bone marrow.
Acute lymphoblastic leukemia is a type of malignancy that most commonly affects children.…
Leukemia is cancer of the blood forming tissues that also affects the bone marrow and the lymphatic system. Such a type of cancer causes abnormal development of cells that gradually enter the bloodstream.
Symptoms of leukemia vary with the type. The common symptoms of the disease include the following: Undue…
Both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are an acute form of leukemia characterized by proliferation of early lymphoid/myeloid precursor cells which replace the normal hematopoietic cells of the bone marrow.
Patients with ALL and AML may present with symptoms related to either…
Myeloproliferative diseases are a collective group of disorders characterized by the clonal proliferation of at least one hematopoietic cell lineage. The ensuing conditions are associated with severe complications.
Myeloproliferative diseases have similar clinical pictures and generally feature nonspecific symptoms such…
Ulcerative colitis (Colitis ulcerosa) is a form of inflammatory bowel disease. It characteristically involves the colon and extends proximally from the anal verge. The exact etiology of ulcerative colitis is unknown.
Individuals with ulcerative colitis can present rectal bleeding, mucous discharge from the rectum, and/or…
Gaucher disease is a lysosomal storage disease in which enzyme deficiency leads to accumulation of glycolipids in various tissues, mainly in the monocyte-macrophage system. It is transferred by autosomal recessive pattern of inheritance and depending on the subtype, patients may present with hepatosplenomegaly,…
Aerobic exercise (also known as cardio) is physical exercise of low to high intensity that depends primarily on the aerobic energy-generating process. Aerobic literally means "relating to, involving, or requiring free oxygen", and refers to the use of oxygen to adequately meet energy demands during exercise via…
Acute myelocytic leukemia is a myeloproliferative disorder characterized by the accumulation of abnormal myeloid precursors in the bone marrow. The disease may be associated with end organ dysfunction resulting from an infiltration with leukemic cells, but mortality is most commonly due to the consequences of bone…