45 Possible Causes for Lytic Bone Metastasis in USA

  • Adenocarcinoma of the Colon
    Lytic Bone Metastasis
  • Adenocarcinoma of the Prostate
    Solitary Lytic Bone Lesion Bone Metastasis Lytic Bone Metastasis

    Symptoms like anorexia, loss of weight, backache, pain in the lower limbs, pain in the bones, and pathological bone fractures may be seen in some cases due to bone metastasis … Symptoms typically appear in advanced stages either due to urinary obstruction or metastasis. … PSA is a tumor marker and high baseline levels are suggestive of a current or future likelihood of metastasis but it does not predict the risk of the disease.[1]

  • Stage IV Prostate Carcinoma
    Prostate Cancer Metastasis to Bone Lytic Bone Metastasis
  • Multiple Myeloma
    Multiple Lytic Bone Lesions Lytic Bone Metastasis

    Bone scans are typically not of any additional value in the workup of myeloma patients (no new bone formation; lytic lesions not well visualized on bone scan). … The presence of unexplained anemia, kidney dysfunction, a high erythrocyte sedimentation rate (ESR), lytic bone lesions, elevated beta-2 microglobulin, and/or a high serum … Myeloma activity sometimes appears as "lytic lesions" (with local disappearance of normal bone due to resorption), and on the skull X-ray as "punched-out lesions" (pepper … [2] [3]

  • Aplastic Anemia
    Bone Metastasis

    The transplanted bone marrow replaces the failing bone marrow cells with new ones from a matching donor. … The disease is also known as bone marrow failure. … Damage to the bone marrow is the main cause of aplastic anemia.[4] [5]

  • Myelodysplasia
    Bone Metastasis

    Bone marrow changes include hypercellularity with dysplastic changes. … Blasts produced by the bone marrow mature into normal blood cells. … The affected bone marrow produces lower levels of different blood cells.[6]

  • Malignant Neoplasm
    Solitary Lytic Bone Lesion

    For painful bone metastasis, it has been found to be effective in about 70% of patients. … Claims that breaking bones resulted in bone cancer, for example, have not been proven. … Metastasis is the spread of cancer to other locations in the body.[7]

  • Osteitis Deformans
    Solitary Lytic Bone Lesion Prostate Cancer Metastasis to Bone

    These localized areas of pathological destruction of bone tissue (osteolysis) are seen radiologically as an advancing lytic wedge in long bones or the skull. … bone remodelling. … This causes affected bone to weaken, resulting in pain, misshapen bones, fractures and arthritis in the joints near the affected bones.[8] [9]

  • African Histoplasmosis
    Solitary Lytic Bone Lesion

    In human disease it manifests differently than histoplasmosis (caused by Histoplasma capsulatum), most often involving the skin and bones and rarely involving the lungs.[10]

  • Reticulosarcoma
    Solitary Lytic Bone Lesion Multiple Lytic Bone Lesions

    One classification system for lymphomas divides the diseases according to the size of the white blood cells that has turned cancerous. The large-cell lymphomas have large cells. A large cell, in this context, has a diameter of 17 to 20 µm. Other groups of lymphomas in this system are the small-cell lymphomas and…[11]

Further symptoms

Similar symptoms


  1. Adenocarcinoma of the Prostate, Symptoma
  2. Multiple Myeloma, Symptoma
  3. Multiple myeloma, Wikipedia, CC-BY-SA-3.0
  4. Aplastic Anemia, Symptoma
  5. Aplastic anemia, Wikipedia, CC-BY-SA-3.0
  6. Myelodysplasia, Symptoma
  7. Cancer, Wikipedia, CC-BY-SA-3.0
  8. Osteitis Deformans, Symptoma
  9. Paget's disease of bone, Wikipedia, CC-BY-SA-3.0
  10. African histoplasmosis, Wikipedia, CC-BY-SA-3.0
  11. Large-cell lymphoma, Wikipedia, CC-BY-SA-3.0