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138 Possible Causes for Macrocytic Anemia, Night Sweats, Pallor

  • Myelodysplasia

    Symptoms are referable to the specific cell line most affected and may include fatigue, weakness, pallor (secondary to anemia), increased infections and fever (secondary to[msdmanuals.com] Medical Importance The myelodysplastic syndromes are clonal hematopoietic disorders that commonly cause macrocytic anemia in older patients.[hematology.org] Signs of transformation to a more aggressive lymphoma include worsening constitutional symptoms (weakness, fatigue, fever, weight loss, night sweats); rapidly enlarging lymph[iwmf.com]

  • Crohn's Disease

    […] which may precede the onset of intestinal symptoms The most common cutaneous manifestations are erythema nodosum and pyoderma gangrenosum Skin examination may also reveal pallor[emedicine.medscape.com] Subjects were excluded if there was a known history of iron deficiency anemia (IDA), 14 UC, or macrocytic anemia.[doi.org] Crohn's Disease Symptom Tips Fever and night sweats can be Crohn's symptoms. Talk with your doctor to be sure.[web.archive.org]

  • Primary Myelofibrosis

    Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org] Skin pallor (caused by anemia) may also be noticeable.[aoporphan.com]

  • Anemia

    Pallor has poor sensitivity for predicting mild anemia, but correlates well with severe anemia. 11 – 13 One study showed that physical examination findings of pallor of the[aafp.org] Macrocytic anemia Possible causes of macrocytic anemia include vitamin B-12 deficiency, folate deficiency, liver disease, and hypothyroidism.[emedicine.com] Consider constitutional symptoms of chronic illnesses (eg, weight loss, night sweats, rashes, bowel changes).[emedicine.com]

  • Autoimmune Hemolytic Anemia

    A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Diagnosis of AIHA is relatively easy given the constellation of laboratory findings of normocytic or macrocytic anemia, reticulocytosis, low serum haptoglobin levels, elevated[jitc.biomedcentral.com] […] and lupus are the two most commonly associated secondary causes of AIHA (albeit rare), patients may present with symptoms specific to the condition such as weight loss, night[clinicaladvisor.com]

  • Acute Myelocytic Leukemia

    […] diffuse rash) Splenomegaly occurs in 50% of patients Bone discomfort (especially in ribs, sternum, and tibia) Older adults may experience delirium, progressive weakness, and pallor[physio-pedia.com] Macrocytic anemia will be present unless there is an associated iron deficiency. Peripheral blood smear shows megaloblastic changes. Serum vitamin B12 levels are low.[online.epocrates.com] sweats easy bruising or petechiae (tiny red spots on the skin caused by easy bleeding) bone and joint pain belly pain (caused by the build-up of cells in organs like the[kidshealth.org]

  • Myeloproliferative Disease

    […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com] , such as macrocytic red blood cells.[doi.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com]

  • Chronic Myeloid Leukemia

    […] insidious, with a nonspecific “benign” stage (malaise, anorexia, weight loss) eventually giving way to accelerated or blast phases with more ominous signs, such as splenomegaly, pallor[msdmanuals.com] anemia, normal to increased platelet count, and increased numbers of megakaryocytes, many of which have hypolobated nuclei.[doi.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com]

  • Acute Erythroblastic Leukemia

    Pallor, sometimes petechiae, bruising, gum and nose bleeding, hepatosplenomegaly, lymphadenopathy, retinal haemorrhage.[patient.info] : hypogranulation, hyposegmentation Megakaryocytes: small, non-lobulated cells Older patients Asymptomatic, or BM failure Macrocytic anemia Low-grade: support, follow.[quizlet.com] Almost half of people with AEL exhibit weight loss, fever and night sweats at the time of diagnosis.[en.wikipedia.org]

  • Whipple Disease

    Fever and night sweats are common, as well as general weakness. There are many further possible symptoms depending on the organs affected.[encyclopedia.com] Systemic symptoms are encountered in about half of patients and consist of intermittent, mostly low-grade fever and night sweats.[prognosisapp.com]

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