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298 Possible Causes for Macrocytic Anemia, Pancytopenia

  • Pernicious Anemia

    Macrocytic anemia incidiously appeared in September 1999.[ncbi.nlm.nih.gov] The outcome was rapidly marked by febrile pancytopenia and ataxia leading to the diagnosis of pernicious anemia.[ncbi.nlm.nih.gov] Abstract An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] […] tur·nal he·mo·glo·bi·nu·ri·a an infrequent disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterized by episodes of hemolytic anemia[medical-dictionary.thefreedictionary.com]

  • Myelodysplasia

    Medical Importance The myelodysplastic syndromes are clonal hematopoietic disorders that commonly cause macrocytic anemia in older patients.[hematology.org] Abstract An 18-month-old boy presented with fever, hepatosplenomegaly, jaundice, pancytopenia, hyperferritinemia, hypertriglyceridemia and evidence of hemophagocytosis and[ncbi.nlm.nih.gov] Initial stages of MDS may be characterized by macrocytic anemia with mild thrombocytopenia or neutropenia.[symptoma.com]

  • Severe Aplastic Anemia

    Abstract Severe aplastic anemia (SAA) is an autoimmune disease characterized by severe pancytopenia and bone marrow failure.[ncbi.nlm.nih.gov] This condition is termed pancytopenia.[symptoma.com] Abstract Severe aplastic anemia is a disorder of stem cell failure, leading to pancytopenia.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] The clinical manifestations of PMF include splenomegaly, consequent to extramedullary hematopoiesis, pancytopenias, and an array of potentially debilitating constitutional[ncbi.nlm.nih.gov] KEYWORDS: Bone marrow aplasia; immunosuppression; myelosuppression; pancytopenia; pegylated interferon-α-2a; primary myelofibrosis[ncbi.nlm.nih.gov]

  • Bone Metastasis

    BMC Surg. 2016 Aug 19;16(1):58. doi: 10.1186/s12893-016-0171-0. Author information 1 Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Beijing, China. 2 Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Beijing, China. [email protected] Abstract BACKGROUND: Malignant thymomas[…][ncbi.nlm.nih.gov]

  • Refractory Megaloblastic Anemia

    Examples include causesof splenomegaly, indications for splenectomy, differential diagnosis of normocytic anemia,macrocytic anemia, hypochromic anemia, thrombocytopenia, bone[books.google.de] We hypothesize that promoter variants in the inducible nitric oxide synthase gene might be the cause of severe refractory megaloblastic anemia and pancytopenia in our patient[unboundmedicine.com] TOC HEME Approach to Macrocytic /Megaloblastic Anemia By means of morphologic and biochemical criteria, macrocytic anemias can be divided into two groups: The megaloblastic[enotes.tripod.com]

  • Homocystinuria without Methylmalonic Aciduria Type cblG

    Serum Macrocytosis Despite megaloblastic anemia being a hematological hallmark of HMAG, it is not a constant feature: Patients have been described to present macrocytic anemia[symptoma.com] […] have to be carried out and provide essential information as to the underlying metabolic disorder: With regard to blood counts, megaloblastic anemia and thrombocytopenia or pancytopenia[symptoma.com] Despite megaloblastic anemia being a hematological hallmark of HMAG, it is not a constant feature: Patients have been described to present macrocytic anemia without megaloblastic[symptoma.com]

  • Transcobalamin II Deficiency

    Complete blood count revealed severe macrocytic anemia (hemoglobin, 2.8 g/dL; mean corpuscular volume, 117 fL), thrombocytopenia (platelets, 117 10 9/L), and normal white[imagebank.hematology.org] CONCLUSION: Transcobalamin II deficiency should be considered in differential diagnosis of any infant with pancytopenia, failure to thrive, diarrhea, and vomiting.[ncbi.nlm.nih.gov] Abstract An infant with deficiency of transcobalamin II (TCII) presented with virtually complete failure to thrive and life-threatening pancytopenia.[ncbi.nlm.nih.gov]

  • Megaloblastic Anemia

    macrocytic anemia.[livehealthy.chron.com] We hypothesize that promoter variants in the inducible nitric oxide synthase gene might be the cause of severe refractory megaloblastic anemia and pancytopenia in our patient[ncbi.nlm.nih.gov] We recently observed a case of severe megaloblastic anemia with pancytopenia in a renal transplant recipient who had been receiving Az therapy for 22 years.[ncbi.nlm.nih.gov]

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