Create issue ticket

139 Possible Causes for Macrocytic Anemia, Primary Myelofibrosis

  • Myelodysplasia

    Medical Importance The myelodysplastic syndromes are clonal hematopoietic disorders that commonly cause macrocytic anemia in older patients.[hematology.org] primary MDS (often RAEB2 ) with fibrosis and therapy related myeloid neoplasms with fibrosis Primary Myelofibrosis, Fibrotic Phase MDS with Fibrosis Post-Polycythemia Vera[surgpathcriteria.stanford.edu] Initial stages of MDS may be characterized by macrocytic anemia with mild thrombocytopenia or neutropenia.[symptoma.com]

  • Polycythemia Vera

    , may have basophils, platelets Anemia, leukocytosis, or nl platelets platelets, often abnormal Dimorphic RBC, platelets Macrocytic anemia, or nl platelets Marrow Myeloids[surgpathcriteria.stanford.edu] Megakaryocytic morphology also differed between primary myelofibrosis JAK2 V617F and essential thrombocythemia JAK2 V617F.[ncbi.nlm.nih.gov] This case report describes the progression of primary myelofibrosis (PMF) to polycythemia vera (PV), and discuss its potential mechanisms.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] […] tur·nal he·mo·glo·bi·nu·ri·a an infrequent disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterized by episodes of hemolytic anemia[medical-dictionary.thefreedictionary.com] Hemolytic Anemia (see Anemia , [[Anemia]] and Hemolytic Anemia , [[Hemolytic Anemia]]) Epidemiology : anemia is the most common clinical finding in PNH Diagnosis Complete[mdnxs.com]

  • Extramedullary Hematopoiesis

    Common causes of EMH include spherocytic anemia, erythroblastosis of newborn, thalassemia, pernicious anemia in period of relapse, macrocytic anemia of hepatic origin, carcinoma[lungindia.com] Primary myelofibrosis (PMF) is a clonal hematopoietic stem cell disorder.[ncbi.nlm.nih.gov] Primary myelofibrosis belongs to the group of myeloproliferative syndromes. Extramedullary hematopoiesis in the liver can lead to portal hypertension.[ncbi.nlm.nih.gov]

  • Myeloid Metaplasia

    Examples include causesof splenomegaly, indications for splenectomy, differential diagnosis of normocytic anemia,macrocytic anemia, hypochromic anemia, thrombocytopenia, bone[books.google.com] Primary myelofibrosis/agnogenic primary myeloid metaplasia What every physician needs to know: Primary myelofibrosis (PMF) is a chronic malignant hematologic disorder that[cancertherapyadvisor.com] , Fanconi anemia , Sideroblastic anemia Blood tests Normocytic - Microcytic - Macrocytic - Normochromic - Hypochromic Other Methemoglobinemia Coagulation / platelets / coagulopathy[wikidoc.org]

  • Primary Myelofibrosis

    To report ocular manifestations of idiopathic primary myelofibrosis in a patient with relapsed primary myelofibrosis. Observational case report.[ncbi.nlm.nih.gov] Primary myelofibrosis terminating in megakaryoblastic crisis is uncommon. A case with this condition is reported.[ncbi.nlm.nih.gov] We discuss some unique characteristics of primary myelofibrosis in children and review outcome data for children with this disease.[ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    , may have basophils, platelets Anemia, leukocytosis, or nl platelets platelets, often abnormal Dimorphic RBC, platelets Macrocytic anemia, or nl platelets Marrow Myeloids[surgpathcriteria.stanford.edu] In the present study LGALS1 and LGALS3 were differently expressed between polycythemia vera, essential thrombocythemia (ET) and primary myelofibrosis (PMF) diseases.[ncbi.nlm.nih.gov] The 2016 revised WHO criteria for the diagnosis of pre-fibrotic/early primary myelofibrosis (pre-PMF) require at least one of the following four borderline expressed minor[ncbi.nlm.nih.gov]

  • Refractory Anemia

    anemia.[omicsonline.org] myelofibrosis.[ncbi.nlm.nih.gov] BCR-ABL1 pos Chronic neutrophilic leukemia Chronic eosinophilic leukemia NOS (see also Idiopathic hypereosinophilic syndrome ) Polycythemia vera Essential thrombocythemia Primary[surgpathcriteria.stanford.edu]

  • Myeloproliferative Disease

    MACROCYTIC anemia with anisocytosis 2. THROMBOCYTOPENIA with variations in PLT size. 3. WBCs may be N/H/L 4.[quizlet.com] myelofibrosis (PMF). 1 patient had unclassifiable CMPD (CMPD-U). 3 patients had overlapping features of ET and PV. 31 patients (14 with PV, 19 with ET, 3 with concomitant[ncbi.nlm.nih.gov] Polycythemia vera, essential thrombocythemia, primary myeolfibrosis The mutation in MPL is sometimes found in: Essential thrombocythemia and primary myelofibrosis The BCR-Abl[quizlet.com]

  • Systemic Mastocytosis

    anemia and thrombocytopenia.[cedars-sinai.edu] In 15 of 65 patients (23%), initial diagnoses by LP were incorrect (by overlooking SM), for example primary myelofibrosis (n 3), myelodysplastic/myeloproliferative neoplasm[ncbi.nlm.nih.gov] In a few patients with SM-AHNMD, the JAK2 mutant V617F is detected in AHNMD cells. 49 In these patients, the AHNMD is often classified as primary myelofibrosis. 49 Other patients[bloodjournal.org]

Further symptoms

Similar symptoms