Macrophage Alveolitis: Causes & Reasons

Possible Causes for Macrophage Alveolitis

Click on photo to see a larger image NGIP/Alveolitis. Small collections of macrophages at arrows. Very early granuloma formation. NGIP/Alveolitis. [granuloma.homestead.com]

Hemorrhagic, necrotizing, and abscessing Staphylococcus aureus pneumonia Hemorrhagic, necrotizing, and infarcting Pseudomonas aeruginosa pneumonia Acute non-necrotizing alveolitis [quizlet.com]

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [lumen.luc.edu]

Extrinsic Allergic Alveolitis

Abstract ICAM-1 expression was studied on alveolar macrophages (AM) in extrinsic allergic alveolitis (EAA) using immunocytochemistry and cytometry. [ncbi.nlm.nih.gov]

alveolitis. [karger.com]

Abstract Expression of the CD14 antigen was studied on alveolar macrophages in extrinsic allergic alveolitis (EAA), using immunocytochemistry and cytometry. [ncbi.nlm.nih.gov]

Pulmonary Histiocytosis X

This difference in the intensity of the cigarette-induced macrophage alveolitis observed in the two patient groups may be important in explaining the opposite effects of cigarette [ncbi.nlm.nih.gov]

21 This macrophage alveolitis is not specific for pulmonary LCH but merely reflects the smoking history of the patients. 21 Total cell counts correlate with daily cigarette [thorax.bmj.com]

CT scan showing nodular lung lesions Bronchoalveolar lavage evidenced an alveolitis with a predominance of macrophages and lymphocytes and a positivity of the anti CD1a at [pubs.sciepub.com]

Extraocular Muscle Myopathy

Simultaneous presence of neutrophil alveolitis and Ki-67 positivity of alveolar macrophages in dermato-/polymyositis and systemic sclerosis. [malattierare.regione.veneto.it]

Respiratory Bronchiolitis Interstitial Lung Disease

—RB-ILD typically manifests as extensive centrilobular micronodules and patchy ground-glass opacity corresponding to macrophage-rich alveolitis (Fig 1), with or without fine [xctmr.com]

alveolitis [[Desquamative Interstitial Pneumonia]]: alveoli filled with macrophages [[Pulmonary Infiltrates with Eosinophilia]]: alveoli filled with eosinophils, macrophages [mdnxs.com]

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [lumen.luc.edu]

Juvenile Dermatomyositis

Simultaneous presence of neutrophil alveolitis and Ki-67 positivity of alveolar macrophages in dermato-/polymyositis and systemic sclerosis. [malattierare.regione.veneto.it]

Honeycomb Lung

[…] fibroblast proliferation macrophages are a major player Idiopathic pulmonary fibrosis: morphology patchy interstitial fibrosis loose nests of fibroblasts type 2 pneumocyte [quizlet.com]

[…] granulomas Histiocytosis histological honeycomb hypercalcaemia infection infiltration involvement lower zones lung disease lung fields lupus pernio lymph nodes lymphocytes macrophages [books.google.com]

Pale or lightly eosinophilic vacuolated macrophages are typically found in alveolar spaces and are a common sign of bronchiolar obstruction. [slideshare.net]

Meconium Peritonitis

macrophagic alveolitis eosinophilic alveolitis fibrosing alveolitis See also pulmonary lesions pulmonary lesional syndromes Pneumonia (pneumonitis) acute pneumonia acute [humpath.com]

PMID: #6693114# NSAID-associated gastritis 16 January 2006 NSAID-related gastritis Alveolitis 16 January 2006 Types acute alveolitis chronic alveolitis lymphocytic alveolitis [humpath.com]

[…] acute bacterial bronchopneumonia chronic bacterial pneumonia Cytology acute bacterial pneumonia The cytology specimen consists primarily of neutrophils and macrophages. [humpath.com]

Interstitial Lung Disease

Macrophagic alveolitis was the most common type found in asbestosis (52.9%). CD4/CD8 ratio was usually decreased or normal. [dlib.si]

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [meddean.luc.edu]

[…] and mixed cell alveolitis. [dlib.si]

Acute Berylliosis

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [lumen.luc.edu]

Macrophage-eisinophil: eosinophils predominate. Examples: acute or chronic eosinophilic pneumonia, drug-induced lung disease. [lumen.luc.edu]

Pulmonary Consolidation

(H&E, ob. x20) Lobar pneumonia, leukocytic alveolitis. [lihyinworld.blogspot.com]

Leukocytic alveolitis is the 3rd phase of the lobar pneumonia. [lihyinworld.blogspot.com]

Alveolar lumens are filled with leukocytic (suppurative) exudate (neutrophils and macrophages, in order to remove the fibrin). [lihyinworld.blogspot.com]

Lipid Pneumonia

It also disclosed lymphocytic (cytotoxic/suppressor) alveolitis. [ncbi.nlm.nih.gov]

Lymphocytic alveolitis was also found (lymphocytes 21%). [elsevier.pt]

BAL analysis showed a marked reduction in the total number of alveolar macrophages; almost 70% of these cells contained intracytoplasmic lipid vacuoles. [ncbi.nlm.nih.gov]

Hypersensitivity Pneumonitis due to Other Organic Dusts

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [lumen.luc.edu]

Macrophage-eisinophil: eosinophils predominate. Examples: acute or chronic eosinophilic pneumonia, drug-induced lung disease. [lumen.luc.edu]

Stimuli such as fibrogenic dusts, immune complexes, and heat-killed bacteria are known to cause the release of mediators from macrophages. [lumen.luc.edu]

Granulomatous Lung Disease

METHODS: Alveolar macrophages from 16 patients with granulomatous lung diseases [8 with sarcoidosis, 8 with extrinsic allergic alveolitis (EAA)], 16 patients with IPF, and [ncbi.nlm.nih.gov]

[…] fibrosis (IPF) and granulomatous lung diseases, we examined the in vitro production of an angiogenic chemokine (IL-8), and 2 angiostatic chemokines (IP-10 and MIG) by alveolar macrophages [ncbi.nlm.nih.gov]

Amyopathic Dermatomyositis

Simultaneous presence of neutrophil alveolitis and Ki-67 positivity of alveolar macrophages in dermato-/polymyositis and systemic sclerosis. [malattierare.regione.veneto.it]

Farmer's Lung

[…] for the development of the observed lymphocytic alveolitis. [ncbi.nlm.nih.gov]

Granulocyte/macrophage colony-stimulating factor could be one factor which may contribute to this alteration. [ncbi.nlm.nih.gov]

In conclusion, a defect in the ability of alveolar macrophages to suppress the proliferation of lymphocytes in the lung of patients with farmer's lung is a major factor accounting [ncbi.nlm.nih.gov]

Acute Interstitial Lung Disease

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [lumen.luc.edu]

It was expressed most prominently in alveolar macrophages and alveolar epithelium of all disorders and in the granulomas of sarcoidosis and extrinsic allergic alveolitis. [thedoctorsdoctor.com]

Macrophage-eisinophil: eosinophils predominate. Examples: acute or chronic eosinophilic pneumonia, drug-induced lung disease. [lumen.luc.edu]

Pneumoconiosis

The sequence of events include alveolar macrophage alveolitis, signaling by inflammatory cytokine, oxidative damage, proliferation and activation of fibroblasts, and metabolism [symptoma.com]

This causes an alveolar macrophage–dominated alveolitis, as demonstrated in Figure 1 ( 12, 13 ). Thereafter, many of the fibers are cleared. [atsjournals.org]

The fundamental lesion in asbestosis is the fibrosing alveolitis around airways. [symptoma.com]

Tropical Eosinophilia

However, a mild alveolitis characterised by hypercellular lavage fluid due to a significant increase in absolute alveolar macrophages (p less than 0.001) and due to an increase [ncbi.nlm.nih.gov]

CT scan showing cryptogenic fibrosing alveolitis. [medassignments.com]

All these mechanisms can attract and activate alveolar macrophages, so that continued antigenic exposure results in the development of pulmonary fibrosis. [medassignments.com]

Asbestosis

This results in a process of inflammation known as alveolar macrophage alveolitis. [lecturio.com]

This may in some patients induce a macrophage-induced alveolitis[ 27 ]. [ncbi.nlm.nih.gov]

Activated macrophages release various cytokines, including tumor necrosis factor (TNF) and interleukin-1beta (IL-1), leading to the development of fibrosis. [lecturio.com]

Hereditary Neutrophilia

Filgrastim Gallbladder empyema Granulocyte colony stimulating factor Granulocyte-macrophage colony stimulating factor Hantavirus Hereditary neutrophilia Hyperimmunoglobulinemia [wikidoc.org]

[…] leukemia Adult-onset Still's disease Aminophylline Bronchiolitis obliterans organizing pneumonia Chronic myeloid leukaemia Congenital syphilis Dinoprostone Extrinsic allergic alveolitis [wikidoc.org]

Chronic Interstitial Lung Disease

Types of Alveolitis Macrophage-lymphocyte: T-lymphocytes and macrophages predominate with a few neutrophils and eosinophils. [lumen.luc.edu]

A mouse model of progressive pulmonary fibrosis, J Clin Invest, 1995, vol. 96 (pg. 250 - 9 ) 22 Cultured alveolar macrophages from patients with idiopathic pulmonary fibrosis [academic.oup.com]

Macrophage-eisinophil: eosinophils predominate. Examples: acute or chronic eosinophilic pneumonia, drug-induced lung disease. [lumen.luc.edu]

Pleural Calcification

There was no lymphocytic alveolitis; macrophages showed no morpholo gical characteristics of activation (Figure 6). 5. [pneumon.org]

The visual field was full of amorphous inorganic material both within alveolar macrophages and in the extracellular matrix. [pneumon.org]

Medium to large macrophages with irregular shape and numerous thin projections, suggestive of cell activation, at least morphologically, were seen. [pneumon.org]

Cryptogenic Organizing Pneumonia

The most frequent BAL profile was mixed alveolitis (62%) with lymphocyte predominance, a CD4/CD8 index of 0.4 and foamy macrophages. [ncbi.nlm.nih.gov]

Moreover, a neutrophil alveolitis is frequently seen in COP. Little is known about the involvement of alveolar macrophages in the pathogenesis of COP. [ncbi.nlm.nih.gov]

Langerhans-Cell Histiocytosis

Thus, BAL rarely establishes a definite diagnosis for PLCH in adults, but rather provides additional orientation by showing macrophage alveolitis. [err.ersjournals.com]

In asympto-matic patients with a typical HRCT pattern and a macrophage alveolitis by BAL, for whom no systemic therapy is required, a presumptive diagnosis may be acceptable [doi.org]

Autoimmune Pulmonary Alveolar Proteinosis

Diffuse alveolar damage, RDS Eosinophils Eosinophilic pneumonia Cholesterol crystals, foreign material Exogenous lipid pneumonia, aspiration pneumonia Exsudative neutrophilic alveolitis [pediatrics.aappublications.org]

progressively replaced by macrophages, giant cells, fibroblasts Meconium aspiration syndrome Lipoproteins, Pneumocystis P jiroveci pneumonia Calcified microliths Pulmonary [pediatrics.aappublications.org]

Filling With Different Materials Leads to Various Disease Entities Material Filling the Alveolar Space Disease Surfactant PAP Erythrocytes, siderophages Alveolar hemorrhage Macrophages [pediatrics.aappublications.org]

Chronic Eosinophilic Pneumonia

Langerhans cell histiocytosis (interstitial infiltrate, Langerhans cells) Extrinsic allergic alveolitis (less edema, more interstitial inflammation) Parasites Fungal allergies [pathologyoutlines.com]

[…] obliterans Blood vessel infiltration by inflammatory cells is common, but no vascular necrosis No diffuse alveolar damage Differential diagnosis DIP (if extensive intra-alveolar macrophages [pathologyoutlines.com]

Secondary Pulmonary Fibrosis

Cryptogenic fibrosing alveolitis (or idiopathic pulmonary fibrosis) Patients with this condition have chronic deposition of inflammatory cells that include macrophages and [lecturio.com]

Current concepts of pathogenesis and treatment of UIP For many years, UIP was considered to be a primarily inflammatory disease that began with an ‘alveolitis’ ( Table 3 ) [nature.com]

The inflammatory response in cryptogenic fibrosing alveolitis is believed to be the first step in the pathogenesis of the condition. [lecturio.com]

Baritosis

[…] corticosteroids cough crackles cryptogenic fibrosing alveolitis deposition diagnosis diameter diffuse interstitial fibrosis disease progresses dust evidence exposure fibrosing alveolitis [books.google.com]

Acute Interstitial Pneumonitis

It was expressed most prominently in alveolar macrophages and alveolar epithelium of all disorders and in the granulomas of sarcoidosis and extrinsic allergic alveolitis. [thedoctorsdoctor.com]

Despite being mostly obtained from animal models, both pathways appear to begin after inhaled antigens are phagocytosed by macrophages ( 4 ). [ncbi.nlm.nih.gov]

The most frequent pattern is a lymphocytic alveolitis with a predominance of CD8 + T-cells. [err.ersjournals.com]