Macular Skin Rash: Causes & Reasons

Possible Causes for Macular Skin Rash

Skin rashes are frequent. A macular erythematous rash may occur in patients with infectious mononucleosis who are treated with ampicillin or amoxicillin. [askhematologist.com]

[…] manifestations like rash have been reported in 3% to 19% of cases of IM.7 Rash can be macular, papular, erythematous, or morbilliform and typically affect the trunk and arms [uspharmacist.com]

[…] complications of IM.5-7 Hepatomegaly is present in only about 10% of patients, and mild-to-moderate elevation of hepatic transaminases and bilirubin can also be found.1,5,7 Skin [uspharmacist.com]

Kawasaki Disease

[…] manifestation is a diffuse macular-papular erythematous rash, which is quite nonspecific.[31] The rash varies over time and is characteristically located on the trunk; it [en.wikipedia.org]

One to two months after the onset of fever, deep transverse grooves across the nails may develop (Beau’s lines),[30] and occasionally nails are shed.[30] The most common skin [en.wikipedia.org]

Chikungunya

Complications such as macular edema, retinal vascular occlusions, and serous retinal detachments have been described. [eyewiki.aao.org]

rash.[6][13] Clinical features may include papillitis, multifocal choroiditis, and retinitis, sometimes with hemorrhages and cotton wool spots. [eyewiki.aao.org]

[…] association with CHIKV.[2][9][10] Visual symptoms of chikungunya posterior uveitis often present several weeks after acute phase symptoms of fever, headache, arthralgia, and skin [eyewiki.aao.org]

Lymphocytic Hypereosinophilic Syndrome

ABSTRACTS: ACCEPTED: COLON—CLINICAL VIGNETTES/CASE REPORTS S1918 Lymphocytic Variant of Hypereosinophilic Syndrome Presenting with Gastroenteritis 1Weill Cornell Medicine - Qatar, New York, NY; 2New York Presbyterian - Weill Cornell Medical Center, New York, NY; 3New York Presbyterian Weill Cornell Medicine, New York,[…] [journals.lww.com]

Carbapenem Allergy

Their patient received an 8-day course of imipenem/cilastatin for the treatment of ventilator-associated pneumonia and developed an erythematous macular morbilliform rash [ncbi.nlm.nih.gov]

Skin prick and intradermal testing completed 6 weeks later was negative at maximum concentrations of imipenem/cilastatin. [ncbi.nlm.nih.gov]

[…] morbilliform rash and increased eosinophil count after 5 days of treatment ● Challenged with meropenem 1 week later ■ Tolerated 14-day course with no reaction ● Prick and [ncbi.nlm.nih.gov]

Cholesterol Embolism

Full Text A 47-year-old hypertensive woman was admitted to the Intensive Care Unit due to abdominal pain and shock with violet macular skin rash ( Fig. 1 ). [medintensiva.org]

Proctitis

One patient developed a macular skin rash 1 week after commencing acetarsol, which resolved within 4 weeks of drug cessation. [ncbi.nlm.nih.gov]

Cholinergic Urticaria

Four patients each had a similar persistent macular skin rash distributed maximally over the upper limbs and upper trunk. [ncbi.nlm.nih.gov]

CU is characterized by generalized flushing, an urticarial rash (2- to 4-mm wheal surrounded by macular erythema), and pruritus ( 11 ). [journals.lww.com]

Many patients note a tingling, itching, or burning sensation of the skin before the appearance of the hives. [journals.lww.com]

Adult-Onset Still Disease

skin rash. [tropicalgastro.com]

It is a non-pruritic, evanescent, salmon-colored, macular or maculopapular type of rash [ 1 ]. [archivesofmedicine.com]

Further, 60–80% of AOSD patients experience a macular or maculopapular evanescent salmon-pink skin rash associated with the fever spiking [ 38 – 41 ]; some patients, those [bmcmedicine.biomedcentral.com]

Interstitial Nephritis

On admission the patient was febrile, with bilateral pedal edema, macular skin rash, and auscultatory finding that suggested pneumonia. [ncbi.nlm.nih.gov]

The illness presented after two weeks of respiratory tract infection, skin rash and hypermenorrhea. [ncbi.nlm.nih.gov]

Piperacillin Allergy

8 52 M Delayed - - - - - + (delayed) Fixed drug eruption 9 68 M Immediate - - - - - + (immediate) Urticaria 10 65 M Delayed - - - - - + (delayed) Macular rash 11 51 M Immediate [ncbi.nlm.nih.gov]

- - - - + (immediate) Urticaria ST, skin tests; DPT, drug provocation tests; PPL, benzylpenicilloyl-poly-L-lysine; MD, minor determinant; PT, piperacillin-tazobactam. [ncbi.nlm.nih.gov]

Immediate - - - - - + (immediate) Urticaria 6 78 F Immediate - + (immediate) + (immediate) - + (immediate) Not done - 7 42 F Delayed - - - - - + (delayed) Maculopapular rash [ncbi.nlm.nih.gov]

Itching Purpura

Skin manifestations: Macular rash appears first on the extensor surfaces of the limbs and buttocks, which becomes rapidly, urticarial and purpuric with central necrosis of [drmhijazy.com]

rash. [drmhijazy.com]

Clinical Manifestations General manifestations: The manifestations usually begin with mild fever, sore throat, and upper respiratory tract infections which may precede the skin [drmhijazy.com]

Complement Deficiency Syndrome

Skin had a macular and petechial rash. Patient had leukocytosis of 25.8K cells/ m L and a severe lactic acidosis. She was aggressively resuscitated. [shmabstracts.com]

Autosomal Dominant Autoimmune Lymphoproliferative Syndrome Type 1

In addition, there were a macular skin rash with telangiectasia and perivascular lymphocyte infiltration, a cytopenia without abnormal cells, a hepatosplenomegaly, a pericardial [ncbi.nlm.nih.gov]

Fat-Soluble Vitamin Deficiency

She presents with a macular-papular skin rash and croup. [medbullets.com]

Cutaneous Mastocytosis

rash that exhibited superficial perivascular mast cell infiltrates on biopsy of lesional skin. [ncbi.nlm.nih.gov]

Skin examination revealed a macular rash, with tan and salmon-colored lesions most notable on the buttocks, trunk and thighs ( Figure 1 ). [aafp.org]

The patient had sicca symptoms with an abnormal minor salivary gland biopsy and decreased salivary flow, peripheral neuropathy, an 80 pound weight loss, and a macular erythematous [ncbi.nlm.nih.gov]

Transient Sarcoidosis

The skin involvement in juvenile idiopathic arthritis is a transient erythematous macular rash whereas sarcoidosis can present with varied skin eruptions including erythema [ijdvl.com]

Biotin Deficiency

Biotin mnemonic Symptoms of deficient biotin intake are: Dry skin Rashes, including erythematous periorofacial macular rash Seborrheic dermatitis Fungal infections Fine and [medicowesome.com]

Conjunctivitis Initial symptoms of biotin deficiency include: Dry skin Seborrheic dermatitis Fungal infections Rashes including erythematous periorofacial macular rash Fine [bodybuildingforyou.com]

Efavirenz Toxicity

Management of rash Mild to moderate skin rash A mild rash is described as a localised macular rash, whilst a moderate rash is a more diffuse macular or maculopapular or morbilliform [mic.uct.ac.za]

rash. [mic.uct.ac.za]

Mild to moderate skin rashes do not present with systemic features. The management involves continuation of efavirenz and symptomatic treatment with oral antihistamines. [mic.uct.ac.za]

Pulmonary Histiocytosis X

Skin and mucous membranes Skin involvement occurs in 34% of patients. Rashes may be macular, papular, nodular or petechial. [patient.info]

Children and adults may have LCH in skin (macular, papular, ulcerative, or seborrheic rashes), bones (painful lytic lesions), lymph nodes, brain (pituitary, cerebrum and cerebellum [rarediseases.org]

Skin rashes in neonates may regress spontaneously. Scalp lesions may be scaly. Any mucosal tissue can be affected; ulceration and bleeding can occur. [patient.info]

Livedo Reticularis

Full Text A 47-year-old hypertensive woman was admitted to the Intensive Care Unit due to abdominal pain and shock with violet macular skin rash ( Fig. 1 ). [medintensiva.org]

Mononeuritis Multiplex

Most common; Rash - Macular Other: Papular, Nodular, Plaquelike, or Pigmented Bone marrow: with More diffuse lymphoma Muscle: Asymptomatic; Intravascular Adrenal: Enlargement [neuromuscular.wustl.edu]

[…] manifestations of Churg-Strauss syndrome include palpable purpura; a macular or papular erythematous rash; hemorrhages (petechiae to ecchymoses); and tender cutaneous or [aafp.org]

VII & Hearing loss Also EOM, Trigeminal Radiculopathy: Pain; Sensory loss; Weakness Organ involvement Eye: Visual loss; Papilledema; Retinal & Choroid vessels involved Skin [neuromuscular.wustl.edu]

Mononeuritis

[…] manifestations of Churg-Strauss syndrome include palpable purpura; a macular or papular erythematous rash; hemorrhages (petechiae to ecchymoses); and tender cutaneous or [aafp.org]

Most common; Rash - Macular, Papular, Nodular, Plaquelike, or Pigmented Bone marrow: with More diffuse lymphoma Muscle: Asymptomatic; Intravascular Adrenal: Enlargement [neuromuscular.wustl.edu]

These skin manifestations may be caused by vasculitis, eosinophil accumulation, or granulomatosis. [aafp.org]

Subcutaneous Abscess

skin discolouration and pigmentation disorder t Dermatitis psoriasiform, exfoliative rash, rash, rash erythematous, rash follicular, rash generalised, rash macular, rash [mymemory.translated.net]

[…] maculo-papular, rash papular and rash pruritic u Skin reaction and skin disorder v Nail disorder and discolouration w Fatigue and asthenia x Face oedema, oedema and oedema [mymemory.translated.net]

Abdominal pain, abdominal pain lower and abdominal pain upper q Gastrointestinal perforation and intestinal perforation r Cholecystitis and acalculous cholecystitis s Yellow skin [mymemory.translated.net]

Microangiopathy

skin rash, myalgias, and prostration. [scielo.br]

[…] year-old girl was admitted to the hospital with a 2-months history of intermittent high fever, migratory polyarthritis involving her wrists, knees, and ankles, evanescent macular [scielo.br]

Adult Idiopathic Neutropenia

Alopecia Pronounced hair loss 2 (or higher) Rash or desquamation Scattered macular or papular eruption or erythema with pruritis or other associated symptoms covering 2 [humanservices.gov.au]

Rash or desquamation Scattered macular or papular eruption or erythema with pruritis or other associated symptoms covering 2 (or higher) Gastrointestinal Diarrhoea Increase [humanservices.gov.au]

Alopecia Pronounced hair loss 2 (or higher) Rash or desquamation Scattered macular or papular eruption or erythema with pruritis or other associated symptoms covering 50% [humanservices.gov.au]

Exanthema Subitum

The rash may appear as separate little raised ("goose bump" size) dots ( papules ) or as a flat (macular) rash. [rxlist.com]

HHV-6-associated ES is characterized by high fever (mean, 39.4°C) lasting 4.1 days, followed by an erythematous and macular or maculopapular rash of 3.8 days’ duration, 21 [dx.doi.org]

The skin is often mildly red in color and temporarily blanches with pressure. The rash is not itchy or painful. It is not contagious. [rxlist.com]

West Nile Encephalitis

The patients’ symptoms included headache, altered mental status, dysphasia, fever, neck stiffness, malaise, arthralgias, and macular skin rash. [ajnr.org]

[…] manifestations specifically rashes, are common; however, there is a few detailed descriptions in case reports and there are few images available. [en.wikipedia.org]

Punctate erythematous, macular, and papular eruptions, most pronounced on the extremities have been observed in WNV cases and in some cases histopathologic findings have shown [en.wikipedia.org]

Ciguatera Poisoning

skin rashes, and hypotension and bradycardia. 2, 5 Although deaths have been reported, 5 ciguatera appears to be rarely life-threatening; however, symptoms are often quite [nzma.org.nz]

[…] pathognomonic of ciguatera poisoning but is also reported following exposure to brevetoxin. 1 Other less common effects include dysuria, pruritis, sweating, nonspecific, often macular [nzma.org.nz]

Systemic Juvenile Idiopathic Arthritis

His fever was accompanied by nonpruritic macular skin rash on his trunk, arthralgia of bilateral ankles and knees, myalgia, and night sweats. [hindawi.com]