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711 Possible Causes for Maculopapular Rash, Thrombocytopenia

  • Infectious Mononucleosis

    A 49-year-old man with diabetic mellitus suffered from IM with fever, pharyngitis, parotiditis with lymphadenopathies, thrombocytopenia and splenomegaly.[] rash.[] An autoimmune hemolytic anemia or thrombocytopenia may also occur. N.B.[]

  • Pharyngitis

    Lymphocytosis, along with greater than 10% atypical lymphocytes and mild thrombocytopenia, can be found in mononucleosis.[] Hepatosplenomegaly also may be present. 10 – 12 If these patients are treated with amoxicillin or ampicillin, 90 percent will develop a classic maculopapular rash. 14 , 15[] Administration of ampicillin frequently induces a maculopapular rash. 1.[]

  • Rocky Mountain Spotted Fever

    This child had no serious bleeding manifestations and minimal hemorrhagic skin manifestations despite severe RMSF, concurrent thrombocytopenia, as well as the coagulation[] The woman presented with a fever followed by respiratory distress, maculopapular rash, and an eschar at the site from which a tick had been removed.[] The combination of fever, headache, myalgias, marked left shift in the differential white blood cell count, severe thrombocytopenia, and hyponatremia all help to suggest the[]

  • Disseminated Intravascular Coagulation

    Both initially received antibiotic treatment for suspected infection-associated thrombocytopenia.[] A 22-year-old Chinese female presented to our medical center with high spiking fever for one week, myalgia for two weeks, and arthralgia and pink maculopapular rash for four[] TAFRO syndrome is a systemic inflammatory disorder that is characterized by thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly.[]

  • Azithromycin

    Laboratory tests revealed severe anemia, thrombocytopenia and an increase in hepatic enzymes.[] After a few days she was feeling better but maculopapular, erythematous rash developed over her palms, accompanied by fever and chills as well as reddish discoloration around[]

  • Valproic Acid

    Discontinuing valproic acid reversed the anemia, thrombocytopenia, and normalized the LDH and haptoglobin, supporting a drug-induced cause for the TMA.[] Skin and Appendages: Furunculosis, maculopapular rash, seborrhea . Special Senses: Conjunctivitis , dry eyes, eye pain. Urogenital System: Dysuria .[] Valproic acid is associated with a variety of hematologic abnormalities, most commonly thrombocytopenia.[]

  • Ehrlichiosis

    […] year-old boy who was referred to the Hematology-Oncology Clinic to consider a bone marrow etiologic process after his pediatrician discovered progressive neutropenia, anemia, thrombocytopenia[] Physical examination revealed a maculopapular rash on her chest, and lung auscultation revealed bi-basilar rales.[] I report a case of tick-borne ehrlichiosis in which the primary presentation suggested an infectious diarrhea, with impressive leukopenia and thrombocytopenia.[]

  • Congenital Toxoplasmosis

    The immediate cause of death was cardiorespiratory failure with antecedent cause of liver failure, renal insufficiency with thrombocytopenia.[] When present, clinical manifestations at birth are maculopapular rash, jaundice, generalized lymphadenopathy, organomegaly, central nervous system anomalies and hyperbilirubinemia[] Further possible manifestations include but are not limited to deafness, thrombocytopenia, myocarditis, pneumonitis, respiratory distress, and nephrotic syndrome.[]

  • Topotecan

    Grade 3/4 adverse events ( 5% incidence) included anemia, thrombocytopenia, neutropenia/leukopenia, diarrhea, fatigue, dehydration, and hypokalemia for topotecan; and thrombocytopenia[] […] includes pruritus , rash erythematous, urticaria , dermatitis, bullous eruption, and maculopapular rash. [ Ref ] Very common (10% or more): Alopecia (49%), dermatologic adverse[] Therapy was well tolerated, with grade 3 thrombocytopenia and grade 2 neutropenia noted after cycle four.[]

  • Carboplatin

    Dose-limiting toxicities included grade 3 fatigue and grade 4 thrombocytopenia; the MTD was not reached.[] The patient had no history of drug allergies or any type of adverse drug reaction, but she developed itchiness, maculopapular rash, sweating, respiratory distress, and anxiety[] DLTs were neutropenia, sepsis, mucositis, and thrombocytopenia.[]

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