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86 Possible Causes for Malaise, Virus Associated Hemophagocytic Syndrome

  • Erythema Infectiosum

    Virus-associated hemophagocytic syndrome.[cmr.asm.org] Typical initial manifestations are nonspecific flu-like symptoms (eg, low-grade fever, slight malaise).[merckmanuals.com] It is a mild, self-limiting 'slapped-cheek' facial rash with low-grade fever and malaise in immunocompetent children.[genome.jp]

  • Infectious Mononucleosis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] A 16-year-old, previously healthy girl presents with a several-day history of fever, sore throat, and malaise. She appears very tired and has a temperature of 39 C.[dx.doi.org] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[emedicine.medscape.com]

  • Chronic Active Hepatitis B

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Transient side effects of malaise and influenza like symptoms occurred in all patients and resolved rapidly after treatment.[ncbi.nlm.nih.gov] Snapshot A 35-year-old presents to the emergency department due to abdominal pain and malaise. He also reports "yellow-ing" of his skin.[medbullets.com]

  • Influenza Pneumonia

    Virus-associated hemophagocytic syndrome (VAHS) refers to hemophagocytic lymphohistiocytosis due to viral infection.[emcrit.org] After an incubation period of a few days, constitutional symptoms of myalgia, fatigue, malaise, anorexia, fever, and a dry cough are main manifestations of influenza infection[symptoma.com] Symptoms include abrupt onset of fever, cough, malaise, myalgia, sore throat, and headache.[health.gov.au]

  • Generalized Herpes Simplex

    Lasserre M, Huguet C, Terno O: Acute severe herpes simplex hepatitis with virus-associated hemophagocytic syndrome in an immunocompetent adult.[link.springer.com] Fever, malaise, headache, and sore throat are presenting features.[www1.cgmh.org.tw] Primary maternal infection may present as a flu-like syndrome with fever, headache, malaise, and myalgias.[perinatology.com]

  • Chronic Active Hepatitis

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] A 56-year-old Saudi male was admitted with abnormal liver chemistry values and a 5-month history of lethargy, malaise, anorexia, and jaundice.[ncbi.nlm.nih.gov] A 27-year-old woman, para 0-1-2-1, presented at 36 weeks' gestation with a 2-week history of malaise, nausea, emesis, diarrhea, and an 18-lb weight loss.[ncbi.nlm.nih.gov]

  • Lupus Nephritis

    However, she suffered Epstein- Barr virus (EBV)-associated hemophagocytic syndrome (HPS) twice, and in each case she was treated with anticancer drugs and achieved a complete[ncbi.nlm.nih.gov] A 78 year old white male on methimazole due to Grave's thyroiditis presented with acute renal failure after a short term history of progressive shortness of breath, malaise[ncbi.nlm.nih.gov] A 20-year-old woman presented with malaise and edema in the lower extremities and face. She had multiple lymphadenopathies.[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis Hepatitis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Symptomatic individuals typically first experience fever, malaise, and fatigue, which is later accompanied by acute pharyngitis, tonsillitis, lymphadenopathy, and/or splenomegaly[amboss.com] Any combination of the following may be present: Headache Fever Tonsillitis / sore throat Cervical lymph node enlargement and tenderness (usually symmetrical) Malaise and[almostadoctor.co.uk]

  • Drug Hypersensitivity

    […] of Epstein-Barr Virus and/or Cytomegalovirus Leading to Hemophagocytic Syndrome in One of Two Patients, Annals of Dermatology, 30, 1, (71), (2018).[doi.org] The most common presentations in patients with DHS are fever, which ranges from 38 C to 40 C and occurs in 85% of cases, malaise, pharyngitis, and cervical lymphadenopathy[mdedge.com] The syndrome may be mild (with arthralgias, fever, and rash) or fairly dramatic (with serositis, high fevers, and malaise), but it tends to spare the kidneys and CNS.[msdmanuals.com]

  • Viral Pneumonia

    Virus-associated hemophagocytic syndrome may play an important role in development of multiorgan failure and ensuing death in H1N1 infection. [28] For more information on[emedicine.com] Presentation Pearls Diagnosis Treatment Media Patient will present as a 45-year-old male with a one week history of hacking non-productive cough, low grade fever, malaise[smartypance.com] Clinical manifestations may include upper respiratory symptoms, conjunctivitis, and rhinitis in association with fever, nonproductive cough, and malaise.[visualdx.com]

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