Male Hypogonadism: Causes & Reasons

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Possible Causes for Male Hypogonadism

Klinefelter Syndrome

Male Hypogonadism. p. 367. CrossRef Google Scholar Amory, John K. and Bremner, William J. 2017. Male Hypogonadism. p. 187. [doi.org]

Affected males carry an additional X chromosome, which results in male hypogonadism, androgen deficiency, and impaired spermatogenesis. [ncbi.nlm.nih.gov]

Klinefelter syndrome (KS) is the most common genetic form of male hypogonadism, but overt phenotype becomes evident only after puberty. [ncbi.nlm.nih.gov]

Kallmann Syndrome

Causes Male hypogonadism means the testicles don't produce enough of the male sex hormone testosterone. There are two basic types of hypogonadism: Primary. [mayoclinic.org]

Swerdloff, Hypogonadism and Male Sexual Function, Pituitary Disorders, (179-192), (2013). [doi.org]

Male hypogonadism that occur secondary to hypothalamic-pituitary dysfunction is known as hypogonadotropic hypogonadism (HH). [dnatesting.uchicago.edu]

Luteinizing Hormone Deficiency

LH mediated high intra-testicular testosterone is essential for postnatal male sexual maturation and spermatogenesis. [endocrine-abstracts.org]

Irvin Hirsch, Male Hypogonadism, Merck Manuals Dec 2014 [dontcookyourballs.com]

Male Hypogonadism. ARUP Consult. Available online at https://arupconsult.com/content/hypogonadism-male?_ga=2.126530189.1479446145.1525530915-171446445.1522145782. [labtestsonline.it]

Primary Male Hypogonadism

Aim: The creation of new experimental model of primary male hypogonadism. [ingentaconnect.com]

NPs must select and follow the best guideline recommendations available to optimally treat male hypogonadism. [nursingcenter.com]

hypogonadism is increasing in prevalence, particularly in the older male population. [journals.lww.com]

Laurence Moon Syndrome

The accepted major criteria for diagnosis include retinal dystrophy, obesity, Polydactyly, male hypogonadism, mental retardation and renal dysfunction. [ijbcp.com]

It may also be associated with hypogonadism in male and complex genitourinary abnormalities in female. [banglajol.info]

Primary Features Secondary Features Rod-cone dystrophy, Polydactyly, Obesity, Learning disabilities, Hypogonadism in males, Renal anomalies. [cureus.com]

Eunuchism

[…] with prune belly syndrome Hypogonadism, male Hypotestosteronism Induced male hypogonadism syndrome Leydig cell failure in adult Male hypogonadism Primary testicular failure [icd9data.com]

It is characterized by the lack of mature male germ cells and testicular hormones. [ MESH : D005058 ] Synonyms: Male hypergonadotropic hypogonadism, Eunuchism, eunuchism, [ebi.ac.uk]

1 / 1 DeCS Descriptor English : Eunuchism Descriptor Spanish : Eunuquismo Descriptor Portuguese : Eunuquismo Synonyms English : Eunuchoidism Hypogonadism, Male Tree Number [decs.bvs.br]

Anorchia

Gynecomastia How can you classify male hypogonadism into 3 types? memorize this 1. [quizlet.com]

Subsequent chapters deal with male sexual precocity; "fertile eunuchism" (Leydig cells reduced in number and size with preserved spermatogenesis); male idiopathic hypogonadism [books.google.com]

Discussions on the current methods for the diagnosis and treatment of male hypogonadism, male infertility and male sexual dysfunction follow, with detailed descriptions of [books.google.ro]

Klinefelter Syndrome with XY/XXY Mosaic

Start Your Free Trial Today Treatment Treatment with androgens reduces gynecomastia and evidence of male hypogonadism and increases strength and libido in patients with all [britannica.com]

hypogonadism and increases strength and libido in all variants. [e-ijd.org]

The presence of acne is driven by the male hormone testosterone along with other factors. [e-ijd.org]

Testicular Atrophy

Male hypogonadism occurs when a man's testicles cannot produce adequate levels of testosterone. According to Northwestern Memorial Hospital urologist, Dr. [livestrong.com]

Hypogonadism Can Result From Defects at Several Levels Last Updated on Sun, 02 Sep 2018 | Skeletal Muscle | Male hypogonadism may result from defects in spermato-genesis, [78stepshealth.us]

Asked 11 Apr 2012 by Anonymous Updated 16 April 2012 Topics hypogonadism - male, testosterone, injection, doctor, sex Details: Ok, so I went to my doctor 6 years ago with [drugs.com]

Andropause

It is imperative that male hypogonadism be evaluated and treated with hormonal replacement to avoid the development of frailty and effects on sexual health. [ncbi.nlm.nih.gov]

hypogonadism (e.g. reduced sexual function, loss of vigor, muscle weakness, depression). [ncbi.nlm.nih.gov]

The nonsexual benefits of testosterone replacement therapy (TRT) in male hypogonadism are well documented, but whether health care professionals (HCPs) and members of the [ncbi.nlm.nih.gov]

Gordon-Holmes Syndrome

[…] reversal after testosterone replacement in a 34-year-old male Owais Rashid et al., BMJ Case Reports, 2017 Adult-onset reversible idiopathic hypogonadotropic hypogonadism [pn.bmj.com]

In 2012, the European Association of Urology published a guideline on male hypogonadism that was developed by European genitourinary surgeons. 28 The levels of evidence were [cmaj.ca]

Adolescents and adults with IGD have clinical evidence of hypogonadism and incomplete sexual maturation on physical examination. [ncbi.nlm.nih.gov]

Prader-Willi Syndrome

Hypogonadism is present in both males and females, and is seen as genital hypoplasia, incomplete pubertal development; and most individuals are infertile. [imprinting-disorders.eu]

Hypogonadism Hypogonadism is a consistent feature of both males and females with PWS. [dx.doi.org]

BMD in the setting of a low estradiol level • Adult males: testosterone replacement as for hypogonadal males. [dx.doi.org]

Pituitary Disorder

hypogonadism. [mayoclinic.org]

Yedinak, Jessica Brzana, and Shirley McCartney 19 Hypogonadism and Male Sexual Function, 179 Prasanth N. Surampudi, Christina Wang, and Ronald S. [wiley.com]

In women, prolactinoma might cause: Irregular menstrual periods Lack of menstrual periods Milky discharge from the breasts In men, a prolactin-producing tumor may cause male [mayoclinic.org]

Hyperprolactinemia

Prolactinomas seem to be less common in males, but in males hyperprolactinemia also causes hypogonadism, which causes infertility and loss of libido. [courses.washington.edu]

[diagnosis and therapy of hypogonadism in adult males]. Urologe A, 43(12):1563-81; quiz 1582–3. Trottmann, M., Dickmann, M., Stief, C. G., and Becker, A. J. (2010). [urology-textbook.com]

Hyperprolactinemia Hyperprolactinemia results in secondary hypogonadism and usually presents in a dimorphic fashion in both females and males. [touchendocrinology.com]

Hemochromatosis

Table 5 compares the hypogonadal males to the nonhypogonadal males. [academic.oup.com]

CASE PRESENTATION: A young Serbian male presenting with end-stage heart failure was referred for extracorporeal membrane oxygenation. [ncbi.nlm.nih.gov]

• Loss of period (premature stoppage of menstruation) • Loss of interest in sex • Depression • Impotence • Hair loss (other than “normal” male balding) • Skin color changes [irondisorders.org]

Testicular Disease

Diabetes is a major contributor to male infertility. Also low testosterone (male hypogonadism) and other hormonal problems are common in infertile men. [edenfertilitycenters.com]

Panhypopituitarism

hypogonadism, and estradiol for female hypogonadism (usually with a progestogen to inhibit unwanted effects on the uterus). [en.wikipedia.org]

[…] indirectly by administering the products of the effector glands: hydrocortisone (cortisol) for adrenal insufficiency, levothyroxine for hypothyroidism, testosterone for male [en.wikipedia.org]

Bjornstad Syndrome

Affected male members were fertile, thus excluding the possibility of hypogonadism, which is characteristic of Crandall syndrome. [nature.com]

Crandall et al. (1973) characterized three male siblings with neurosensory deafness, pili torti-induced baldness, and secondary hypogonadism. [news-medical.net]

All affected males were short in stature and had lean bodies (height, 156.3±4.5 cm; weight, 40.3±4.5 kg) as compared with the normal males of the family (height, 176±5 cm [nature.com]

Cryptorchidism

Male hypogonadism: an extended classification based on a developmental, endocrine physiology-based approach. Andrology. 2013; 1:3-16. 18. [revistas.uis.edu.co]

Biemond Syndrome Type 2

hypogonadism (micropenis, small testes). [accesspediatrics.mhmedical.com]

Testosterone is also used as a medication to treat male hypogonadism, since testosterone levels gradually decrease as men age, synthetic testosterone is sometimes prescribed [wikivisually.com]

Hypogonadism with Mental Retardation and Skeletal Anomalies Male Pseudohermaphroditism/Mental Retardation Syndrome, Verloes Type Malouf Syndrome Mandibulofacial Dysostosis [rgd.mcw.edu]

Myotonic Dystrophy

hypogonadism and cardiac conduction defects [ 1 ]. [bmcresnotes.biomedcentral.com]

Organ system Manifestations Gastrointestinal dysphagia, gastroparesis, constipation Ocular cataracts, ptosis Endocrine hypogonadism (males), hyperinsulinism CNS excessive [cancertherapyadvisor.com]

A 74 year-old male presented to endocrine clinic with hypercholesterolemia (serum LDL-C 210 mg/dL), hypogonadism, insulin-controlled type 2 diabetes mellitus, and minimally [ncbi.nlm.nih.gov]

Launois Syndrome

Testosterone modulates serum leptin concentrations in a male patient with hypothalamic hypogonadism. J Endocrinol Invest. 2000;23:246-50. [rarediseases.org]

Froehlich Syndrome

Testosterone modulates serum leptin concentrations in a male patient with hypothalamic hypogonadism. J Endocrinol Invest. 2000;23:246-50. [rarediseases.org]

It affects males more than females. [homeopathyworldcommunity.ning.com]

The disorder is more common in males. [medicalalgorithms.com]

Congenital Disease

Females with PMM2 -CDG have hypergonadotropic hypogonadism, which affects the production of hormones that direct sexual development. [ghr.nlm.nih.gov]

Affected males experience normal puberty but often have small testes. More than 800 individuals with PMM2 -CDG have been identified worldwide. [ghr.nlm.nih.gov]

Ataxia Telangiectasia

hypogonadism impaired spermatogenesis Neoplasia: leukemia hodgkin lymphoma non-hodgkin lymphoma increased risk in heterozygotes Immunology: defective b cell differentiation [malacards.org]

[…] gonadal dyfunction in two males and three females diagnosed with A-T between ages 4 and 23 years. [oncofertility.northwestern.edu]

[…] synopsis from OMIM: 56 Neurologic Central Nervous System: seizures tremor myoclonus dystonia choreoathetosis more Growth Height: short stature Genitourinary Internal Genitalia Male [malacards.org]

Autoimmune Polyendocrine Syndrome

Researches revealed that the testis-expressed protein TSGA10 is also a target of immune reactions in male hypogonadal patients (59). [doi.org]

In one man the hypogonadism was hypothalamic in origin rather than primary. [nejm.org]

Self-Abs against scc, but not 17 α -OH, were associated with hypogonadism (16). [doi.org]

Noonan Syndrome

and delayed puberty in affected males or females, sex hormone replacement therapy may be considered in some cases. [rarediseases.org]

[…] cases, renal malformations, oral anomalies (high arched palate, malocclusion, impacted teeth, retroclined mandibular incisors), coagulation defects, hypogonadism. [amhsr.org]

In addition, because deficiencies of certain hormones (gonadotrophin) may contribute to abnormally decreased function of the gonads (hypogonadism) and delayed puberty in some [rarediseases.org]

Hypothalamic Dysfunction

hypogonadism and infertility 9.1 Definitions and classification of disorders 9.2 Normal male endocrinology 9.2.1 The male gamete: spermatogenesis, maturation, function 9.2.2 [oxfordmedicine.com]

LH was normal in most children, but low ( CONCLUSIONS: Pubertal development in PWS females, as in males, is characterized by normal adrenarche, pubertal arrest, and hypogonadism [ncbi.nlm.nih.gov]

Endocrine and local testicular regulation 9.2.3 Testicular hormones 9.3 Evaluation of the male patient with suspected hypogonadism and/or infertility 9.3.1 Clinical appearance [oxfordmedicine.com]

Hypogonadism

MALE HYPOGONADISM 2. [slideshare.net]

How does my doctor tell if I have male hypogonadism? How is male hypogonadism treated? What is male hypogonadism? [dartmouth-hitchcock.org]

MANAGEMENT OF MALE HYPOGONADISM 22. GOAL THERAPY MALE HYPOGONADISM  SHAFIRA BINTI SHAHAMEN (10-6-104) 23. [slideshare.net]

Malignant Lymphoma of the Testis

A nineteen year old Kenyan male presented with a twelve month history of rapidly progressing painless swelling of both testicles. Pre-operative clinical and laboratory evaluation resulted in clinical suspicion of bilateral testicular tumour confirmed by ultrasonography. Bilateral inguinal orchidectomy was effected and[…] [ncbi.nlm.nih.gov]