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988 Possible Causes for Male Sterility, Mutations in the Cystinosis Gene, Subsarcolemmal Accumulation of Normal Mitochondria

  • Cystic Fibrosis

    Male sterility is a constant feature. Late-onset forms, which are usually only mild or monosymptomatic, have also been reported.[orpha.net] This effect has subsequently been demonstrated in a number of models of other diseases caused by stop mutations, including muscular dystrophy, 15 Hurler's syndrome, 16 cystinosis[doi.org] They may experience delayed puberty, or reproductive abnormalities such as sterility in males. Over ninety-percent of males with Cystic Fibrosis are sterile.[disabled-world.com]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Malnutrition

    The modern contraceptive methods for men are limited to male condoms and sterilization (vasectomy).[who.int] sterilization (vasectomy) Permanent contraception to block or cut the vas deferens tubes that carry sperm from the testicles Keeps sperm out of ejaculated semen 99% after[who.int] 97–98% with no semen evaluation Female sterilization (tubal ligation) Permanent contraception to block or cut the fallopian tubes Eggs are blocked from meeting sperm 99%[who.int]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Cystinosis

    Fertility status in male cystinosis patients treated with cysteamine.[ncbi.nlm.nih.gov] Patients with less severe cystinosis gene mutations tend to have better kidney outcome.[cjasn.asnjournals.org] Besouw MT, Kremer JA, Janssen MC, Levtchenko EN : Fertility status in male cystinosis patients treated with cysteamine. Fertil Steril 2010; 93 : 1880–1883.[nature.com]

    Missing: Subsarcolemmal Accumulation of Normal Mitochondria
  • Chronic Alcoholism

    The study group consisted of 55 heavy-drinking males diagnosed with alcohol abuse, while the control group consisted of 55 males without a history of alcohol abuse.[ncbi.nlm.nih.gov] Samples were taken from the inferior fornix conjunctiva with sterile cotton-tipped swabs (Amies transport medium) for culture.[ncbi.nlm.nih.gov]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Obesity

    The prevalence of obesity and overweight increased in the United States between 1978 and 1991. More recent reports have suggested continued increases but are based on self-reported data. To examine trends and prevalences of overweight (body mass index [BMI] or 25) and obesity (BMI or 30), using measured[…][ncbi.nlm.nih.gov]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Urethritis

    The purpose of the present study was to determine pathogens and behaviors associated with nongonococcal urethritis (NGU) and the usefulness of the urethral smear in predicting the presence of pathogens. We conducted a case-control study of men with and without symptoms of NGU. Sexual practices were[…][ncbi.nlm.nih.gov]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Morbid Obesity

    Morbid obesity is associated with liver pathology, most commonly non-alcoholic steatohepatitis (NASH) leading to cirrhosis. However, the morbid obesity impedes qualification for organ transplantation. We present a case report of a 56-year-old woman who underwent bariatric procedure followed by liver transplantation[…][ncbi.nlm.nih.gov]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Chronic Prostatitis

    The term prostatitis refers to an inflammation of the prostate gland. A prostatitis is considered chronic, if inflammation and accompanying symptoms persist for more than a few weeks. Bacterial CP Symptoms associated with bacterial CP include pain at the penis' base, around the anus, in close proximity to the pubic[…][symptoma.com]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Chronic Kidney Insufficiency

    Chronic kidney insufficiency affects a significant number of individuals in the developed countries, particularly the United States. The progressive nature of the disease and a substantial reduction in the quality of life over the period of time are the primary reasons why an early diagnosis is crucial. Anemia,[…][symptoma.com]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria
  • Orchitis

    Regarding male sterility and types of orchitis, bacterial orchitis can be treated and has better odds than those provoked by the mumps virus, which can produce sterility in[invitra.com] The possibility of sterility occurring in males lends particular interest as this is the most serious complication of the mumps syndrome.[jpbsonline.org] The testicles may become atrophied, but sterility from this cause is uncommon.[britannica.com]

    Missing: Mutations in the Cystinosis Gene Subsarcolemmal Accumulation of Normal Mitochondria