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120 Possible Causes for Marked Macular Degeneration, Mutation in the TTLL5 Gene, Severe Color Vision Defect

  • Cone Rod Dystrophy Type 15
  • Familial Benign Flecked Retina

    Neovascular (Wet) Age-Related Macular Degeneration: the RIVAL Study First Author: Mark GILLIES (Australia) Poster No.: P-075 Phase IV Ranibizumab Study Investigating Re-Treatment[2015.apvrs.org] Severe color vision defect: usually present only after VA worse than 20/40. Dark adaptometry: Abnormal cone portion and normal rod portion until late.[cram.com] Criteria for a Treat and Extend Protocol in Patients with Neovascular Age-Related Macular Degeneration (Namd): the FLUID Study First Author: Jenny ARNOLD (Australia) Poster[2015.apvrs.org]

    Missing: Mutation in the TTLL5 Gene
  • Cystoid Macular Dystrophy

    degeneration (ARMD) Cystoid macular edema Diabetic retinopathy Glaucoma Inflammatory eye diseases (i.e., retinitis, iritis, keratitis, and scleritis) Retinal arterial occlusion[articles.mercola.com] As the disease progressed color vision deteriorated (type 1 acquired red-green defect), disturbance of the electro-oculogram became more prevalent, and the electroretinogram[ncbi.nlm.nih.gov] Sorsby’s Macular Dystrophy Sorsby disease is also called macular cyst, or cystoid macular degeneration. Symptoms usually begin between 20 and 40 years of age.[lowvision.preventblindness.org]

    Missing: Mutation in the TTLL5 Gene
  • North Carolina Macular Dystrophy

    Currently, there are no published guidelines to prognosticate STGD macular degeneration.[retinatoday.com] […] cone-rod dystrophy AD (majority) AR 1st–2nd decades; may not be detected early in course of disease Decreased central vision (20/40–20/200) defective color vision; severe[entokey.com] Progression of visual field changes can be expected, and marked abnormality of both cone and rod systems is detected with ERG.[retinatoday.com]

    Missing: Mutation in the TTLL5 Gene
  • Peripheral Cone Dystrophy

    Molecular validation of the candidate variants The novel mutation in the TTLL5 gene (c.182–3_182–1delinsAA) was validated using conventional Sanger sequencing according to[molvis.org] Currently, there are no published guidelines to prognosticate STGD macular degeneration.[retinatoday.com] In the AMD group, color vision defects were more severe with increased reduction of visual acuity.[jamanetwork.com]

  • Chronic Alcoholism

    […] forms of malnutrition and vitamin deficiency, color vision dysfunction appears to be associated with decreased visual acuity, contrast sensitivity losses, visual field central[scielo.br] defects, and anatomical signs of retinal damage, such as degeneration of the papillomacular nerve fiber bundle and atrophy of the temporal optic disk (Plant & Perry, 1990[scielo.br] […] chronic alcoholism, whether attributable to long-term exposure to ethanol or large quantities of daily ethanol intake, or because of the association between alcoholism and severe[scielo.br]

    Missing: Marked Macular Degeneration Mutation in the TTLL5 Gene
  • Pterygium

    Age-related macular degeneration is a chronic eye disease marked by deterioration of tissue in the part of your eye that's responsible for central vision.[marylandeyedocs.com]

    Missing: Mutation in the TTLL5 Gene Severe Color Vision Defect
  • Macular Degeneration

    Macular degeneration is deterioration in the central area of the retina, called the macula, said Dr.[livescience.com] Mark Fromer, an ophthalmologist and retina specialist at Lenox Hill Hospital, in New York City.[livescience.com]

    Missing: Mutation in the TTLL5 Gene Severe Color Vision Defect
  • Uveitis

    Morland, Mark W. Greenlee and Frans W. Cornelissen, Morphometric analyses of the visual pathways in macular degeneration, Cortex, 56, (99), (2014).[doi.org]

    Missing: Mutation in the TTLL5 Gene Severe Color Vision Defect
  • Cavernous Hemangioma

    Physical examination Depending on the size and location of the cavernous hemangioma, exam findings may range from normal to severe axial proptosis with poor vision, elevated[eyewiki.aao.org] […] intraocular pressure (IOP), motility defects and a relative afferent pupillary defect.[eyewiki.aao.org] Physical exam should include assessment of visual acuity, pupillary reaction,color vision, Hertel exophthalmometry, intraocular pressure, slit lamp exam with fluorescein and[eyewiki.aao.org]

    Missing: Marked Macular Degeneration Mutation in the TTLL5 Gene