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234 Possible Causes for Massive Splenomegaly

  • Non-Hodgkin Lymphoma

    INTRODUCTION: Extraintestinal manifestations of nontyphoidal salmonellosis are usually seen in patients with cellular immunodeficiency. Pleural empyema caused by nontyphoidal Salmonella is very rare clinical presentation of salmonellosis and there are just a few cases described in a literature. We presented a very rare[…][]

  • Lymphoma

    T-cell CLL usually is a more aggressive disorder than B-cell CLL, with massive splenomegaly, marked neutropenia, skin infiltration, modest bone marrow infiltration, and a[]

  • Primary Myelofibrosis

    Abstract Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by progressive anemia, massive splenomegaly, leukoerythroblastosis, extramedullary[] She also underwent splenectomy when she was 13 years old, due to massive splenomegaly, anemia and various infection disease episodes.[] Treatment may include hydroxyurea for thrombocytosis and massive splenomegaly, androgens, erythropoietin, or red cell transfusions for severe anemia, local irradiation of[]

  • Chronic Lymphocytic Leukemia

    splenomegaly and occasionally lymphadenopathy; prognosis is often poor.[] […] or rapidly progressive splenomegaly uncontrolled autoimmune cytopenias rapid lymphocyte doubling time: either occurring in less than 6 months or when there is an increase[] Bulky disease was defined as the presence of lymph-nodes more than 5 cm in longest diameter by CT and/or ultrasound examination or the presence of massive splenomegaly (6[]

  • Leukemia

    Featured Content Editorial 14 December 2018 Announcement We would like to thank all those listed here for taking the time to review for Leukemia over the past year. Your generosity is much appreciated and we hope your association with the journal continues in the future! Announcement Join the Leukemia Twitter[…][]

  • Splenic Vein Thrombosis

    Routine ultrasound examination in the fourth month of the pregnancy revealed massive splenomegaly of unknown origin.[] Seven of 9 patients (78 %) with massive splenomegaly ( 20 cm) developed PSVT compared with 4 of 13 patients (31 %) with moderate splenomegaly (15-20 cm) and 6 of 45 patients[]

  • Gaucher Disease

    CONCLUSION: HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[] Although Gaucher disease generally presents with massive splenomegaly, which one of the predisposing causes of a wandering spleen, literature shows only one report of a wandering[] Here we present a 36 year old male patient presenting with hip pain showing bilateral avascular necrosis of femoral head with massive splenomegaly and on evaluation, showed[]

  • Hepatosplenic Lymphoma

    Most patients had massive splenomegaly, and bone marrow showed sinusoidal involvement by lymphoma.[] A CT scan revealed a liver with cirrhotic changes without focal lesions and massive splenomegaly with axillary, retroperitoneal and inguinal lymphadenopathy ( Figure 1 ).[] Figure 1 A coronal view of the chest and abdomen obtained with the administration of contrast material, shows a cirrhotic liver with massive splenomegaly Notably, the patient[]

  • Mantle Cell Lymphoma

    Splenomegaly is often massive, while aberrant WBC count may be seen, either as markedly high leukocytosis or pancytopenia.[] The clinical presentation involves generalized lymphadenopathy, splenomegaly that is often massive and systemic symptoms, primarily because the vast majority of patients are[] […] why almost 70% of patients present in late stage of the disease, which is characterized by fatigue, systemic symptoms and the appearance of generalized lymphadenopathy and splenomegaly[]

  • Splenic Subcapsular Hematoma

    Bedu-Addo G, Bates I (2002) Causes of massive tropical splenomegaly in Ghana. Lancet 360: 449-454.[] Splenomegaly is most commonly asymptomatic in Sarcoidosis but when massive (3% of patients) it also can be a cause of massive splenic infarction [ 17 ].[] In the tropics, the most common causes of massive splenomegaly include malaria (hyper-reactive malaria), schistosomiasis, and visceral leishmaniasis [ 14 ].[]

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